PlantSME Plant secondary metabolism enzyme database

CpluGWHAMMO000009620293630.1 calohypnum_plumiforme

Protein ID: CpluGWHAMMO000009620293630.1
Record level: protein/isoform record
Species：Calohypnum plumiforme (calohypnum_plumiforme)
5
Assignments
Phylogenetic Position
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Annotation Path
Each assignment is summarized in the order Pathway -> Module -> Family -> Library -> Method.
Pathway Alkaloid pathway
→
Module Alkaloid portable pathway
→
Family TRI/TRII
→
Library Alkaloid Official Library
→
Method blast+hmm
Pathway Phenylpropanoid pathway
→
Module Phenylpropanoid portable pathway
→
Family CCR
→
Library Phenylpropanoid Official Library
→
Method blast+hmm
Pathway Terpenoid pathway
→
Module Terpenoid portable pathway
→
Family MDS/IspF
→
Library Terpenoid Official Library
→
Method blast+hmm
Pathway Flavonoid pathway
→
Module Flavonoid portable pathway
→
Family 4CL
→
Library Flavonoid Official Library
→
Method blast+hmm_conflict
Pathway Rosmarinic acid pathway
→
Module Rosmarinic acid portable pathway
→
Family 4CL
→
Library Rosmarinic acid Official Library
→
Method blast
Annotation Details
Pathway Module Family Library Method
Alkaloid pathway Alkaloid portable pathway TRI/TRII Alkaloid Official Library blast+hmm
Phenylpropanoid pathway Phenylpropanoid portable pathway CCR Phenylpropanoid Official Library blast+hmm
Terpenoid pathway Terpenoid portable pathway MDS/IspF Terpenoid Official Library blast+hmm
Flavonoid pathway Flavonoid portable pathway 4CL Flavonoid Official Library blast+hmm_conflict
Rosmarinic acid pathway Rosmarinic acid portable pathway 4CL Rosmarinic acid Official Library blast
Protein Sequence
MSGVRQIRGRHLMHPRRTDAAISKGAQHVGFDPCRPRLLAPGPRRQLGDMTQRMLVGLGAGDRGGKQLAAERHHDLVPPD
PNPSPELRPITPLRPGVSVSLLNCLPRGSSKARRRLLLWRRTWLTVCGRSFCVRFQLSQDRRCGRGSCEVVGRVKFRRLS
KGTVKWFNAEKGFGFIAPEDGSADVFVHYTEIQGSGFRTLEENQRVEFEVGQSPKGPQATGLSFFSAESVPPSVADLTGV
LAAAGQIVTVGSGARLSVVVDQAWRARALGQMIDEAGLTSEITETDEHTPLVRTAVDVRLRPIAGEWIRGAVKTVPPLWL
PGPRELRAWTLAGGSPDADRYLLGLDPHAPDTHSPLASALMRVGIAPTLIGTRGARPALRISGRRRLSRLVADGGNGATR
RLVIVESPTKARKLAGYLGSNYIVESSRGHIRDLPRAAADVPAKYKSEPWARLGVNVDHDFEPLYIVSPDKKSTVTELRG
LLKDVDELYLATDGDREGEAIAWHLLETLKPRVPIKRMVFHEITEQAILDAAANPRDLDTDLVDAQETRRILDRLYGYEV
SPVLWKKVAPKLSAGRVQSVATRIIVQRERDRMAFRSAAYWDVVAELDASVSDPTASPPRFTARLTTVDGLRVATGRDFD
SLGQVRKPDEVTVLDEAGAVSLATGLRGSQLTVGSVEEKPYTRRPYPPFMTSTLQQEAGRKLRFSAERTMSIAQRLYENG
YITYMRTDSTTLSQSAINAARTQARQLYGEEYVYPSARQYTRKVKNAQEAHEAIRPAGETFATPDAVRRELDGDEFRLYE
LIWQRTVASQMADARGTTLSLRINGRADGPQTREVQFSASGRTITFAGFLKAYVETVDELAGGEADDAESRLPQLTQGQR
VDAADLTPDGHSTNPPARYTEASLIKALEELGIGRPSTYSSIIKTIQDRGYVHKKGSALVPSWVAFAVIGLLEQHFGRLV
DYGFTAAMEDELDAIASGTERRTNWLNNFYFGGEHGVDDSIARSGGLKKLVGVNLEGIDAREVNSIKLFDDAEGRTVNVR
VGRNGPYLERMVVGDDGEPTPQRANLHDSLTPDELTLDVAEELFATPQEGRSLGVDPESGHEIVAKDGRYGPYVTEVLPK
PDDDEGTEGQPAKKGKKPTGPKPRTGSLLRSMDLQTVTLDDALKLLSLPRVVGVDPESNEEITAQNGRYGPYLKKGTDSR
SLATEDQIFDVTLEEALKLYAEPKRRGRQGAAAPPLRELGTDAASGKPMVIKDGRFGPYVTDGETNASLRKGDDVLSITD
SRASELLADRRARGPVKKTAKKAAAKKTPAKKAAKKTPAKKAAKRSYVLIVAPSSPPLRDVEVPALQLSNNSHDNPDANG
WSIADLLQTMGGGVETPVVVQNITESDAGVLQSGQPSSVPGLSDLLNLGNDPRNHLGHVPAKRLGIQRVADRDRRGEHVT
LLQLGQLGEPGGLVDRIADDGVLEAGQRADVSGDRAARRHPDAELGRPDHRQQFVVQFAGRSQRAAGGVRVFDRGPENGQ
RRVTLELVDEAAVPADGVDHDPEEFVEHADHLGGRPRRGQLGRTDQVDEQHRDVALLPAQLGAALERPAGDVLADVAAEQ
VAQPLPLGQVADHVVEPGLQQAQLAGVVDLHVRVVVTALHFPQRPAQLAQRVGDRHGHQQRAGQPDAECQDRQQQDRVQQ
LLRRPVQVLRLVADHGQHDRQQRHAGRQRPGQHLAADHAGSPDVFRQPAAQGRHGDRSQHTFGLQIADDRGRGGPQAGRD
GHHRRRVMAHRPARDDEHHTADQPGRQVDHGPVERCPQGPAAGQLGGGGVGVGQQAVAALPAEHRHQQPRADRSTDAEQH
HDRRNEAGQVHRRQLLQLDAVFRRVCARTTGRIPGFVSAVPLPCSPAHRIGRRGPKSSQNGRMRWSTVSAGRRRPLLLPV
MSRVFARLVGQESVEADLVAAASAARGDSTHSAAMTHAWLITGPPGSGRSVAALCFAAALQCTSEGLPGCGECRSCTTAM
AGTHGDVRRVIPEGLSIGVDEMRAIVQTASRRPSTGRWQIVLIEDADRLTEGAANALLKVVEEPPPSTVFLLCAPSVDPE
DIAITLRSRCRHIALVTPPPDAIAQVLIDSDGLSAETATWAASVSGGHVGRARRLATDPDARERRMQALGLARDAATRSK
AFASAEALVSSAEAEASVLTADRDEAETEELRTALGAGGTGKGAAGALRGSAGALKDLERRQKSRQTRASRDALDRALID
LATYFRDALLVAANAPGPRANHPDMAEQIASMAAHVPADRLLRCIEAVLECREALAINVKPKFAVDAMVRSSILLGGSHV
VGPSARHDVAHRPRGDTHAQRRGVGPHPDCVTRAGQSHEHPVEPGMYRNPGGGSVGQCHRHRTVAVGEVVHLSRPIRGQQ
RTVETDLDRMVGLHQVAASRNGSGLHRAHPGDLRVDQSTVDADPRRGQTQRRRPQSDAATPHRRQRCVIALHMAQKRDHR
ERDEGNHRGLLEEQQTAEVGQCAGERIPLSAGANQQNRVGAHPGHCGQHRQRVQSRRPPGEPGDAQRGEQCESQRHQQHR
PPPEDHAQSSQQRQRRQQLQHHQAQRRSDPVQGSQPGDGTSDQKRGRHHMAVMVVEQKRRREQTVRAGATDHWRAMSAAA
ASATVGNRAARRYGEPVRALVTGAAGFIGSTLVDRLLSDGHTVAGLDNYASGRATNIEHLADTSEFSFVEADIVTADLKA
IFDEHRPEVVFHLAAQIDVRHSVADPQFDASVNVIGTVRIADAARQTGVRKVVHTSSGGSIYGTPPTYPTSEAVPTDPAS
PYAAGKVAGEIYLNTFRHLYGLECSHIAPANVYGPRQDPHGEAGVVAIFAQALLSGKPTKVFGDGSNTRDYVFVDDVVDA
FVKASGADGGGQRFNVGTGVETSDRQLHSAVAAAVGAPDDPEFHPPRLGDLKRSCLDISSAAGVLGWRPQVLLDAGPPDF
GHGSVWTGGPPSSPVPWCCWPWPGCCPRFHGDEVSTVVAEQAEPASFTSRNPLEYVPGVLLLVAIGLLGKYAQVWLNSLA
HQHHWRVPDIEYVLWAIVIGLFVTNTIGLHRIFRPGVQTYEFWLKIGIVALGVRFVLGDVLRLGGISLLQILVDMVLAGG
IILAAAHVFGLSGKLGSLLAIGTSICGVSAIVASKGAIRARNSDVGYAITAILALGAVALFALPVLGHTIGLTDHEFGLW
AGLSVDNTAETTATGYLYSEQAGKIAVLVKSTRNALIGFVVLGFALYWSSRGEADDIAPGFRARAAFVWDKFPKFVLGFL
AVSAIATAGWLSKGQTTNVANVSRWAFLLTFAGVGLNTNIRELVRTGWRPLVVAVIGLVVVAAVSLALIGAQRAEAECDD
QRVQHQEPVDDDVDAVEQRLPLGRGVLGVEHLDGLFGYPPTVFVDQHDEFGGVTHPVHGDVQPVGDGLVEHPQPVVGIGQ
AQPPAACAERRGGLQHNAFQQRRTADTVAESGSDDDVDRVRAQPVDHREHVGDTVLAVGVEGGEDPGAGLATGVLDAGLD
GGALPQVHRVPHEMRSGLPRDVGGVVGAAVVHADHVRENRPQLADHVADDARFVVGRHHDPDVARFTGHVKATRYTQFSG
RYVQARSGARRCRRADRTGARPRCGSPTAAAVTAAASRRPSRTPSPARRSGAARRRRSRHRLPCIAVSGTSSGARVSVTA
RMTTPPWAPSWLEVTLSSTGKPITRIAPAPAAVIECAAPRRNVAVLPGVSSRAAARVAGDTAIMISQATAPATVAHRNPT
SPQPIRTVAVATATRMTASVTISDPYCVQRLVPASMPSSVACRQKPASPTLSSATDSQCDWANTWLLHSGELPAMTTVAP
TPTIAATRIGCQTVGGAGDQSECSPEHGEDRKAGRRQVTGGQTARGGEYSRTAESSSRCPASGDRLAGRRASDGGRDLWL
STTGGIPMHVHLLEWIFTLVVTIAVLLFDVFVMGRGSGEPSMRRSALGLSAYIGLAICFGVWTWFFHGQQYAIQFFAGWL
TEYSLSVDNLFIFVIIMASFGVPRIYQREALFIGIVIALIFRGVFIALGAAAIQRFTWVFYIFGAFLVYTAVRLARGATH
DGQTENALVRFARRRMSVTDDWHGRRLVVTDRAANGAARRSITPMALVVLALGATDLVFALDSIPAIYGLTSEPYLVLAA
NVFALMGLRQLYFIVEGLLQRLVYLSKGLAVILVFIGVKLILHALRENDLPFVNGGKNIDVPEIPTPALEFAAGPGVCAV
ALLRRCRLVSGQAKQVLCPRQSLLVVLGEVAAPSANRLGLGDLERADVLVHGLAVFELRVAVADQVVGVLRTQQVGPLPG
LVEGHGQRVAQVGHHRKVEQPGDVDLVVQPAGIGPVMRGKEFDGLAALAVLGGPSAAGRLRDRDLGLLLEPVLLQPPDGS
PFVGCCDRAYGTEDRAAEREEQPPEAGGEMCRAHLARMPPRARGFDPKAFAHSRTPVRAVSVTLVFEALDRALHLGFGFL
AAHPVGGLDELARLERLVLREEVLDLVELMLRNVADVLDVVPAVVLGRYAEHLVVAAGLVGHPEHSDRPDLHHDTREHRL
RQQHQRVQRVAVLAESVVEEAVVSGVDHRGVEGSRATWLRRGLAHNRRKQGRRVMRPTMWRTSTHLIVGAGVLAIVAVLV
AAAALLTSTDRAAGAHVPPPPAAVTLKPGVVAVADNAPMPSHSGLAAALAVVAADPNLGKLGARVTDAMTGEELWQQFDD
VLLQPASTNKTLTSAAALLALDRNARVTTRVLAADDSGTIVLVGGGDPTLSGAAPGQDTWYHGAPRLSDLADQVRRSGVT
PTAVEVNTSLFTGPSFAPGWDPADIDGGDISPIESVMLDAGRIQPATDESRRSTTPALDAGHALAAALGVDPQKVTVTNE
PVPTSARQLAAVQSAPLIDRLNEMMNASDNVMAECIAREVAASMQRPLSFTGAVSAVTNRLNTAHVDTGSAILRDSSGLS
VDDRLTAKTLDGVVQAAAGSDEPKLRPLLDLLPIAGGSGTLSDRFLDATFHAAGPAGWLRAKTATVGRRLARPGPPATEY
TRRQAIENLTAAAKAAEPPVRDVTGLHTDAAVAEARIVDRPGWIGAAAESMRAMTGGTDKPRGSISGRITGAQTGAVLAF
VATGILGQFDPFNDGGTLLLVYPNVIAVERQLRVDPSDFRLWVCLHEVTHRVQFTANPWLSGYMSQALGVLTTDSNDDLA
QVVGRLAEFARSRGDSAPADPNSAGVLGLLRAVQSEPQREALDQLLVLGTLLEGHADHVMDAVGPVVVPSVSSIRARFDE
RRNRKQPPLQRLLRALLGIDAKLSQYTRGKAFVDQVVDRVGMTRAVAELRTAVAAFTAEHLATADRWCVALSGGPDSLAL
TGIAVSILPTTALVIDHGLQPGSAEVAAEARRQAERLGCLAAQVIRVEVGRDGGLEAAAREARYRALADARDGQPVLLAH
TLDDQAETVLLGLGRGSGARSIAGMRPYDPPWCRPLLAVRRVTTHAACEELGVNAWHDPHNVDPRFTRSRLRHEVLPLLE
EVLGGGVAQALARTATALRGDTALIDELVDQASSKAATPGGLDARVLAALPDPVRRGVIRGWLIAGRGCGRVCAAPATVG
RRPTRRRFDAAPGAGLVLGARTWHAIRVAAESPELYPGDIKSVLLREDEIQSRIAELGAQIGDEYRDRSTGDGHDLLLIT
VLKGAVMFVTDLARAIPLPTQFEFMAVSSYGSSTSSSGVVRILKDLDRDIHDRDVLIVEDVVDSGLTLSWLLRNLATRRP
HSLRVCTLLRKPDALRANTDIAYVGFDIPNEFVVGYGLDYDERDHGCQHLRGPLGRVDGDLDRVLGVVAGDRIVGSVLRL
ELDPRGGDVLAIDSRTGQRADQILLTLVGEIDRRGGFGCVELDADVGGEGVGHALHVARADNGHLTRMFAYRLRGVVARG
RGRGVGDDVESAVPPAPHQVEDQRHRKPAAERDPGVPVQAEQDVGARGDGQDRRHRVAGDPEPARQFGLLDAQHDHPRRH
HDEGRERADRHDLGQPVQRDHRRQHGHAEGHDHRVADGRHRARVHLGERGRKQPVPAHREQDAGLAVQRHQCDREDRNDS
ARSDNGATRGVAGDVVQNHRQDRLLALEVLPPLRADRGDRHQQVDGRHDQQRGDDRPRHGPLRVFDLVTGGRHRVESDVG
EEDRAGRQADAGHPERCQIVKVVRLESRESDGGKEHQHTDFDDHHDGVRLGGRAGAANQQQRAQRHQDDGRQVDQAALRI
PRRRGNGLRDNESEDVVEQLVQILAPADGHCGDRSQARRNTGDDERDDHRRAGLWHRLREHDENAGPDGLADPEHGQQKD
SEAAFQVIRCAHRDRGPADRPTAQHLPSQGGRRRWHGASSRSIRGRDGGTVDCFGCRQLLHVELDRVSCSPRTRSSTKPS
ARTPPPSRTSWQRCWPPAPAPTRPPRPPTPQRSDRSAVTMLDFAALPPEVNSGLMYAGPGSGPMLTASSAWASLSAELST
VASAYDAVVATLTDGSWLGPAAASMAASSQAQVEWLTSTGVLVEQVSAQAAAAVSAFEAAFNATVPPPEIAANRALLAAL
VSTNLLGQNTPAILATEALYAEMWAQDAAAMYGYAGASSAASTLTPFVTAAESANPAGLGAQAAAVSQAVGSSAGQSAVT
DTLAALAGEMPAPPWMGNLDNFLNALGLSGHVWNSNGDGIVVGGSLGDILEGLTGSQTLDGSTPFDTFIKLISPFRLSTT
ATKDIEGLAEAASKSFGGATKAAAVEAIPAALPPPTLPSGVSGGALGGLGKADLVGRLSVPPNWGGVSPSVSPAVTSVGN
LGTPVSSQPLTPVANSTGAPPVMAGNTGRGMQFASPRYGFKPTVPVSGVVDQHLAVPARHHLGRPVGTHEAEHRVVGAAD
EHGRHVDGGGGRIRHQFPVAVEVAVPVESAGEAGPLELGDVVVDFLRRDPIRQAVGLRQPVDEAGRPGRDHPQCRRRVVR
TGQPTEHSGDRPARVGVELGVGDARLLEIEHVEEVVAEDRPECRGRRDLGAWHRRHAHADNGRDPVRADQVGGEFGDVVG
SDIGRAWGAAVPALVGGHHVVAGGGQHRDLVAPGVRRLGKAVCQHDDGCAGLSRLEGVQLHAVGLDGPFGDGLAVRHSDD
TRGFKPVDTSVATSQIKAGNVKSAQIDDREQQVRLTLKSPATGTEGSDKIITHFPTGYAVPLYDQLSAKDAQVGTVVNQG
SIIGSIVVYVLPLLLLVGLFFMFSRMQGGARMGFGFGKSRAKMLNKDMPKTTFGDVAGADEAVEELYEIKDFLQNPTRYQ
ALGAKIPKGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRDLFEQAKQNSPCIIFVDEIDAVGR
QRGAGLGGGHDEREQTLNQLLVEMDGFGDRTGVILIAATNRPDILDPALLRPGRFDRQIPVSSPDLAGRRAVLKVHSKGK
PFGPDVEFDGLAKRTVGMTGADLENVINEAALLTARENGTVITGAALEEAVDRVVGGPRRKSRIISEQEKKITAYHEAGH
TLSGWAMPGLDPVYKVTILARGNTGGHALAVPEDDKGTHTRSELIARLVMALGGRAAEELVFHEPTTGAVSDIQQATKIA
RAMVTEFGMSSKLGAVKYGSEHGDPFLGRTMGNQADYSHEVAREIDEEVRKLIEAAHTEAWEILTEYRDVLDTVAGELLE
KETLHRAELEAIFADVEKRPRLTLFDEFGGRIPSDKPPIKTPGELAIERGEPWPKPTPEPAFKAAIAAAAREAAQAEAER
GTNGVNGSHGGPPPSTQPDYGAPAGWQAPGWPPQHPGQQQPGYWYPPQAPPQHWPTPPPQHTGQPYPPYPPYPPPGAPAP
ETGQAADPPSGDPNSPAFDHARAEAAVRELLLAIGEDPDRHGLADTPARVARSYQEMFAGLYTDPDTVLDTTFDEQHDEL
VLVKEIPLYSTCEHHLVAFHGIAHVGYIPGRDGRVTGLSKIARLVDLYAKRPQIQERLTTQIADALMRKLDPRGVIVVIE
AEHLCMSMRGVRKPGAVTTTSAVMGVVNVTDDSFSDGGRYLDADRAVEHGLALVAEGASIIDVGGESTRPGATRVDPQVE
IARVAPVVKALAAQGVTVSIDTMHADVARAALESGASMVNDVSGGRADEAMAGLLAEADVPWVLMHWRSVSAAEPHQAAP
YRDVVSEVRTELMACVEHAVAAGVNPSKLVIDPGLGFAKSARDNWALLNALPELVAGGVPVLVGASRKRFLGSLLSDPGG
QARPPDGRETATAVVSALAALHGAWGVRVHDVRASVDAVKVVQAWTRGGAHERTDGQDFVVDVTVWIELADAAASDELAD
TYDYGVLAERAAAIVAGPARNLIETVAGDSAQAASSHSAVLRRCRRRGPPLPARRTGSGGAVMTRVVLSIGSNLGDRQAR
LQSVLDRLGDKVQAVSPVYETAAWGGVEQGPFLNAVLIAEDATLDGQGWLRCAQEMEVAADRVRGQKWGPRTLDVDLVSC
HLTSLDGDSELFSLEDGLTLPHPLAHLRAFVLIPWLAVDPDASLTVAGGRQPAHRHRPRAAHRKLMGPTRKRDLTAAVLG
TAVVGYLLVIGLYRWFPPITVWTGLSLLAVAIAEAMWARYVRAKIVAGEIGDARGRLHPLAVARSLEVAKASAWVGALAL
GCGRRPGWVLLTALLVLAIGASSALVFTSKVELLKLAVILALWAAVVAAFVSVIYRRQSDIDQARARDLKLVYDLQLDRE
ISARREYELTVESQLRRELATELRAQSADEVSELRAELAALRTNLEILFDAELSDRPALESDRTRVRGYSEWERDNESAR
ERINRVASVRAEEPARRVDDTIIDVHEEPLVPPPPPPPQQPRQPAAETYHQAYAPPPPDAYPPPRPSRAPEPPEPDRGSH
RRAAEQETPRSEPAPTGGWTPPQAPSPPERQHEGWPQQQGQPSGWPPPSPPPTTGPQRFEPQPPRRSHRRAEAPNPPEPQ
FAPPPQPEPVQPPPSEPVQQQPRIPWPPPGGGPRQPEQPAASWQPAPSEGQWLPPGAPGSNWNPSATENSAAKSSWAYDN
GPSRDIGSHRSPSAGEPAAEPPPERRGRHSSAPADQTGDPNTEWAESGRRSRSRHSSDTAEPTGSAAPAPAMSPPPSPPP
PPPTPAPDRGPVMSPPPPANARHRSTDEPAEAEEPQSGGQSFDGLRPARLKVGIVSAGRVGTALGVALERVDHVVVACSA
VSRASRQRAERRLPDTPIAAVPDVAGNAELLLLAVPDTELPGLVTGLAATAAVRPGTIVVHTSGVNGIDVLAPLGDCIPL
AIHPAMTFTGAQEDIARLPDTCFGITAADEVGYAIAQSLVLEIGGEPFRVPEHARTLYHAALAHAGNHIVTVLTDALDAL
RAAVSGTELLGQQLVDDQPGGIAERILGPLARAALENTLQRGQAALTGPIARGDAGVLAGHLHALRDVDPALAQAYRVNA
MRTAEKVHAPDDVLEVSRALRHTGRRVMLVPTMGALHDGHLALVRAAKLVPGSVVVVSIFVNPLQFGADEDLDAYPRVVE
SDLALLREAGVEIAFTPSASAMYPDGPRTTIHPGPLGADLEGSARPTHFSGMLTVVCKLMQIVAPDRIFFGEKDFQQLVL
VRQMVADLNIGVRVVGVPIVRENDGLAMSSRNRYLSAAERELATVLSAALTAGAYAAPGGPDAALDAARAVLSEVPAIDV
DYLEVRDSGLGPAPATGAGRLLVAARLGRTRLLDNVAIDIGTTADLHYVGSVTIDADLMDAADLLEGEQVTIVDIDNGAR
LVTYAITGQRGSGVIGINGAAAHLVHPGDLVILIAYAQMEDAEARAYQPKIVFVDAENNAVDLGSDPAFVPEDAGELQWR
IRTEAEITADELALTIDGLIGDDSDQLTGASALSTVPSVLHEVRVMLEQYWPTVPHVLIEPGVRTGIPLLVDNPKEVGAD
RIVNCLAAFQKYNTAAIVIDFGSSICVDVVSAKGEFLGGAIAPGIQVSSDAAAARSAALRRVELARPRSVVGKNTVECMQ
AGAVFGFAGLVDGLVGRIRGDVDGFAGDNVTVVATGHTAPLLLAELDSVDHYDQHLTLHGLRLDDPQDLPEQFRIRRDKR
ERLAAEGRDPYPVDVPRTHTLAQIRAAYPDLPADSTTGDIVGVAGRVVFARNSGKLCFASLQDGDGTQLQVMLSLASVGQ
QALDEWKADVDLGDIVFVHGEVISSRRGELSVLGDSWQMASKSLRPLPVAHKEMSEESRVRQRYVDLIVRPQARTVARQR
IAVMRALRNALEQRGFLEVETPMLQTLAGGAAARPFVTHSNALDIDLYLRIAPELFLKRCVVGGFEKVFEVNRVFRNEGA
DSTHSPEFSMLETYQAYGTYEDSAVVTRELIQQVADEAIGTRQLSQPDGSVYDIDGEWASIQMYPSLSEALGDEITPNTK
VDRLLAIAASLGVEVPKDRGYGHGKLVEELWEHTVGSTLTAPTFVRDFPVETTPLTRQHRSIAGVTEKWDLYIRGFELAT
GYSELIDPVVQRERFAEQARAAAAGDDEAMLLDEDFLAALEHAMPPCTGTGMGIDRLLMALTGLSIRETVLFPIVRPQNY
PAGAVRARVLYGKCLRRKHEAQPMAKKVTVTLVDDFDGEGAADETVEFGLDGVTYEIDLSAKNASKLRNELKQWVEASRR
VGGRRRGRSSTGRGRGAIDREQSAAIRDWARRNGHSVSTRGRIPADVIDAVVVLAQEEARMLNHNYIGTEHILLGLIHEG
EGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAA
QVLVKLGAELTRVRQQVIQLLSGYQGKETAEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERVM
QVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGD
IILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEPTVEHTIEILKG
LRDRYEAHHRVSITDGAVAAAATLADRYINDRFLPDKAIDLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDA
QDFEKAASLRDREKQLVNQRAEREKQWRSGDLDVVAEVDEEQIAEVLGNWTGIPVFKLTEAETTRLLRMEDELHKRIIGQ
VDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGY
VGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDGQGRTVDFKNTVLIFTSNLGTSDISKAVGLGF
TQGGGENNYERMKQKVNDELKKHFRPEFLNRIDDIIVFHQLTKEEIIAMVDLMIGRVGKQLKAKDMAMELTDKAKALLAK
RGFDPVLGARPLRRTIQREIEDQLSEKILFDEIGPGQLVTVDVDNWDGEGNGEDAVFTFAGARKPAEPDLASTGAHAAAG
FDVGEFPIGDRRDPGDGEQAHDGQAGVVEVNAADPTGDRVDPVQVVVQDRDQFDRPDQQRHRDGKTGDGKVVVDLSHRLH
ERPVVGHRHQQPVEGVHQRHARREQQRHHQHRVPRETGRRSAAGQRQQRDLGGGIEAQTEQRAHRVQLNRAGDAVHDRPQ
QSREESPIIERRFDFAVGVRALPKFGERSVDPDQRDHIHDGDQVEEKARGEGAGEAEQVAGGRGFVGQRADGPRPEHDQH
GHHQHQRGMAHREPESNRLGSLAVGHQLARGVVDRGDVVRVEGVSQPEKHPAGDGRPVVARPVQLEADHPRLSVVVDGVP
AERQVTGKATGFRCNVGPLVAIEIDTRGGVQDLLDRLRGADRAGLQRYVHPADVFGVAVPLRARLGRRNVGAVRIRLIYG
RIGSLKQLGTVFGRAVLPLRAQIRTPPRNGEQFVHRRKRRHGGRIVMAGVDQGGVHRLRADSLDQHVGRHVVARRDHLLG
GQAHRNLCSHRQIHARTDSFALVGDGQLVVPGHCPGLDGVGHGVQDVAAPALMSTPRSVKGRSHQSFSIMVWTWPAILGV
ASVPMPTGPIGHSEFSMSSVCWARRPAGVRMSICRLPAAAFADGERDGAQPGVRAMSSAAAASAATGRQRERLRRLLAGS
GNVQHNLELQQRRAGRHRVLALARVRLDGRSGGPRLEGLLGLPLGHHEVPVLALGGAEQLKAEKTGRVLDGVCALGSVYT
YDAPWHRGRDVEDPFPIGTERFVADLGDAVASLGGPARLIGHSMGGLHSWCLAADRPELVTSLIVEDMAPDFRGRTTGPW
EPWLRSLPVEFDSADQVLAEFGDVAGRYFLEAFDRTATGWRLHGHTSRWIEIAAEWGTRDYWAQWQAVRSPALLIEAGNS
VAPDGQMQAMNEKGYRTTYLRVPGAGHLRESPVAGLGHQPVGQQRLQRSIALHGVAQPDHVEFVAGDRRLARRGYPNLPQ
ARTISPAPAAAVADGVGHRAIQSRQIGSTRATGVCCSMNSLTMICHGVTSGCRQGRSRAERAYHSKSSLCVSASVMAYYG
TMSAMPNTDPITAWKALKEGNERFVAGEPQHPSQSVQHRASLAKGQKPTTALFGCGDSRVAAELIFDQGLGDMFVVRTAG
HVIDSSVLGSLEFAVAALGVSVIVILGHDSCGAVKATLSALDDGALPGGYIRDLVERVTPSILLGRREGLTRPDEFEARH
VVETGTQLVERSSAIAAAVAAGDLAIVGATYHLADGRVVIRNIIGEVGDKALEQSAVGGPVLEDRAQPCRGVIERVRDVD
VGDQAAGVGGPGRVGEFRRRQPQVFDMRGEQADQRLEQSTVLEVRLEVGHPVAVQREDRRRVDVVRRHVAQDAAEAEIRQ
KCVRQVGPEDPVEVGDQVRPGAGLGERRVADEDEVQVLRRNAVRLEPGHGNRLRGRALRVAEDRQRVLGVERARVGVEFV
PDGKDDVVGGGEAARALLDQFGRDGRPGRATVEAQRVQVDVFGGLREGGRRHRLGGAAEDDRRVTARQRAKERVVGVGGL
TAQDSGSTGQQAHRGELREHLVSVHRCAPFDVSRSPLPPEIYWRRRGLAIGIAVVVLAIVVAIIVAVLSGSSGADSSAAK
KPTQNSQGANPEVKSPVDPPAGEDPGQPAETPTAAVQPPPVLNAGDDCPDSTLAVKGLTNAPQYATGDQPKFVMVVTNIG
LVACKRDVGAAVLAAYVYSLDNKRLWSNLDCAPSNETLVKTFAPGEQVTTAVTWTGMGSAPHCPLPRPAIGPGTYNLVVQ
LGNLRSLAVPFIMAPPLPPGAAPPAPPAAVPGPPAQGPLPAENPCQRCEVEQLGIGHVVQLVECRGDLGLGERLGVGVIV
AHHQLAGGLVAAEQLFELEPQLAAVGAEFDHLVVEFDADSADQLEALHHGHHVAQCHEIFDLGARQLPADLVEPGLVALQ
RRDGLVGPRQDGRRVGQDMAFAAEVDGYDAHRVADRDHRIADLAGGSFGRPVPGAGLVGRYRRVGHQLHVGPQDPAAVGG
QHHRAVHLAQLTQSGCPARSGRRSVRAGCAPGRRAAQYPAPAALPPHAGWDAAEPSRSSKSCRQSSPLIVRCPRRVQGIR
GRSRLLGTLGDVEDVLQRGADIGRLQGLQAGWHADAARRDQRGGEALSGGLGQPPFHAADPAQIAGQPDFADHHRGGRHR
QVRIRGRQRDRDSEVRRRVGQPHSAHGRQVDVVDGDLEPAVLLQDGGDHRRPRMVDPADRAARRATRRRGQQRLDFAHQR
PLAVQRHRDRRARDRLWPLIQEQPGRVGDTLDPVVLQYETSDFVGGAEAVLHAAHHTQQRIAIAFEVQYHVDQMLERTRP
GDGAVFGDVSDQNERHPGGFRGGGQRGRHRTHLRHAAGDTVGVRAGHRLHRVDHHKRRLHGFDMRQHGVQIGVCGQVQLV
VAATGPVGTHPDLAARLLAGYVQRAPPGRRPLMGDLEQQRRLAHPRIAGQQRHRARHDSAAENTVEFVDSGGAVASSVRL
DGADRYGRCRRADDGAAAAADRAEHRDLVDRSPGEVIVRAVGDRLAQRDGGLDRVGRLDRVVGLLGLAVLADEQHAAGRQ
RGIAGHGHLADVGGDAEQLVADVGGLVDRDQNQGDVLHHRLIAVDGRLLHGGLGDLAGATPGDRDGAQHGARGKRCELCR
ATRCRDAVVEAVHLKPPARPSKPCGPTMHSSRSLGPAKAEGGAIETRTIKGEQKEYLVLKVAQGDLTVRVPAENAEYVGV
RDVVGQEGLDKVFQVLRAPHTEEPTNWSRRYKANLEKLASGDVNKVAEVVRDLWRRDQERGLSAGEKRMLAKARQILVGE
LALAESTDDAKASIILDEAFYQLDGYTLVERAVTGLLESGVVDRVVVAVPADRTDRAKLILGRDATVVAGGANRGDSVSR
ALAAVGEQDQPDFVLVHDAARALTPPELVVRVVEALQAGHPAVVPALPVADTIKAIDANGAVLGTPERAGLRAVQTPQGF
MTELLLRAYQQAGGRGRSAGLQDHHPAGPAVGASDREPVNARIGLGTDVHVIEAGRPCWLLGLLFPEVDGCAGHSDGDVA
VHALCDALLSAAGLGDIGEVFGVDEPRWAGVSGMTMLRHVAELLGEHGFRVGNAAVQVIGNRPRVGPRRAEAQTALAEVL
DAPVSVSATTTDGLGLTGRGEGRAAIATALLVSWHVVTDCADLRLHDTATGAVRDFVPLRPGHVSIYLCGATVQGLPHIG
HVRSGVAFDILRRWLTASGCDVAFVRNVTDIDDKILNKAAAAGRPWWEWAATYERAFSAAYDALGVLPPSVEPRATGHIT
QMVELIERLMESGNAYAACGDVYFDVLSYPDYGQLSGHRIDDVHQGEGTATGKRDQRDFTLWKGAKPGEPSWPTPWGRGR
PGWHLECSAMARTYLGPEFDIHCGGMDLVFPHHENEIAQSCSAGDRFARYWLHNGWVTLGGEKMSKSLGNVLAIPAMLQR
VRAAELRYYLGSAHYRSMLEFSETALKDAVNAYVGIEEFLHRVRTRVGAVEPGQWTPRFAAALNDDLAVPAALAEVHRTR
AEGNRALDAGDHDAALASAGAIRAMMGILGCDPLDERWESRDETSAALGAVDVLVRAELERRQQARVQRDWKLADEIRDR
LKDAGIERRGAIRKSSKKGPTVGSGGQRRRGLEGRGATPPAEARPHHPAAKRAKAQARRPVRRKDDGFETVLGRNPVVEC
LRAGVPATALYVALGAQADERLSESVTLAADSGIAILEVPRSDLDRMTTNGLHQGIALQVPPYAYLHPDEMIKTALDNPP
ALLVALDNISDPRNLGAIVRSVAAFGGHGVLIPERRSASVSAVAWRTSAGAAARLPVARATNLTRTLRDWADRGVQLVGL
DADGDTIVDDVDGTSPIVVVVGSEGKGLSRLVRQNCDAVVSIPMSGPTESLNASVAAGVQVRQRSHIGQVRPDVHADQDG
EDRCRARRRDQRDQHQRGRQIVGDVGQHGGQRRVAEQSEQAGSGRHHRAHPLGNTVSHHRLHDHGQREHEHQERHVRRSD
DCHHRGAPTRKVARREHNRSRQRRTRRRHPERFGDHETDQRQGHHHQGEYRCPGCGFVLLGLGLHVEITMEEDPEHHVDG
AHRGQPRHRHHHAEFDERQLGGVEGEQACGRTGARRRRTVVNTTGVSSTTVASRLRAAVMTAAITNTCPSSRREPTCPRA
MAAPAASNNPSSSHILASTSTAPRNATTGSSRSASTTESCTEIAPTATSNSAAGTATTASGHPRGRATANARTAASDARA
RSSVKLAPMGLRAATPSACPARRRHARRGRSGCEAKHPDRRRHTARPATALTVAGRSRPSAPGPPVAPRPSALFPPSSRG
RMFPVVGRAGPRRGRRRRRAAHPASLSRSRRCPGSAVACSTAGDARTSPTPRRTGDGATLPTPTRARLGREKKPSVITAE
DPSSISSVETPSHVTVSAASDSATGTIDAVGFEPVPDRRGDLHGARRITVHAYRFRVQADRRSVYGRDGTRGHHGEHALG
DCGRIVEHGAGLAPRNQPAVRTIGAIGERLSHGAHAAVVGLVEEGRAREAQHRTPRCPTPVPAPRGRRSGRPRRLAGDVG
AGDDAEHGLVVAEAPDAEALTEIGVEVDAGHVRQLRRAAAGTFGPVTIDGKVVAITGASSGIGEATAYLLAERGARLVLG
ARGAEKLDAVAARLAAAGADVVSAVTDVSRREDVANLVALATETYGRLDVLVSNAGVMPVSPLDELSVDDWESMVDVNLK
GVLFGIAAALPVFRSQGSGHFVNTASTAAFRVTPGQSVYAGTKMAVRAVSEGLRQEAGENLRVTIISPGMTSTNFAESIA
DTATRAALEQRRDEIAMEPAAVARAIAFALEQPADIDVGEIVCMSPLPRRRATLASLAAELKVSRTTISNAYNRPDQLSD
ALRERVLATAKRLGYAGPDPVARSLRTRRAGAVGLVITEPLTYSFSDPAALDFVAGLAQSCESSGQGLLLVAVGPSRSVA
DGTASVLAAGVDGFVVYSAARDDPYLQVVLQRRLPMVVVDQPKAVPGASQVGIDDRAAMREMADYVLGLGHREVGLLTMR
LMRDRHQGLVDLKRLRSTTFHVQSERIHGVRDAMAAIGLDPDSLTVVESHEHTATSGGVAAQIALQANPRITALMCTADV
LAVSAMDYLRARGKFAPGQMTITGFDGVPEAMSRGLTTVAQPSLQKGRRAGELLLSGGLDPTVESDRQLESLAHVGGRRA
PGQPGQQVVGPHIRDHPGDVILLLGRLPVAHRAGEHRVDELLHLVDLAGRRGVGEHVGAGHGLGQQRIALHRAVQFADHE
VESLARCPADHAGAVGLGVDAFELAAQRGHQQMHLRRKVAVQRAHCDVRAVGHGPHLNSLVAALGSDRHRRVEDALATLP
LCLGAEFRLGQYRHVHHLTSSFSLRSLETIRMPSANIPPPCGRDTGMSCCDGIRLDGRTLALLEHVLVLRVASPAAPFPV
DPGVQVAVNTDTISSEQFAARELVRDWAAGSGATAAARDIEQGEPKAWQPVFDGLAGLGLFGVAVPEELGGAGGSIEDLT
AMIEEAARALVPGPVASTALATLVVSDPQLRAALSAGERTAGVALDGDLEFDEPAARVSGTVPWVLGGVEGGLILVPAGD
TWLLVDGAADGVALEPVQATDFSRPLARVVLTSAPATVIDAPAGWVTDLTATVLSAEAAGLTRWTLDTAVEYAKVREQFG
KPIGSFQAIKHLCAEMLCRTEQVAVAAADAARAAQDGDARQLSIAAAIAAGIAIDAAKANAKDCIQVLGGIGITWEHDAH
LYLRRAYATGQFLGGPAHWLRRTAELTQDGVRRDLTIDLSDVEDLRPEIAEAAQGVAGLADDRRQAQLAQAGLLAPHWPT
PYGRGAGPAEQLLIDQELATAGVSRPDLVIGWWAAPTILEHGTPEQIERFVPATLSGEIYWCQLFSEPGAGSDLASLRTK
AVRVDGGWELTGQKVWTSSAHKAQWGVCLARTDPSAAKHKGISYFLIDMSAPGIVIRPLREITGDALFNEVFLDNVFVPD
ELVVGTVNDGWRLARTTLANERIAMAAGTALGNPMEELLAEAAKADLDVAQQDQLARLIITAQVGSLLDQRIAQLAVGGK
DPGPQSSVRKLIGVRYRQALAEFRMDLSDGHGIAFDKTVKDFLNTRCLTIAGPTMGTVLIPIPDRDFDPTEVAVSWQVLR
AGGHRVVFATESGTPGVADDIMVTGRGLDLWSKVPVLRAFTVVGRALRANKDARNAHREMLLSPEYQNPTRWADATLDGV
DALLLPGGHRARGMRSYIDSAILQRLVVDAFARKLKVAAICHGVLLAARSVDPATGHSVLYGRRTTALTWALERTAWRLS
RVTRFWDRDYYRTYGEEPDQPSGYMSVQSEVTRALENPADFHDVEKGSPHYRTKTSGMARDSVTDSKPAFVVDDGARRRD
VVPALDHLDARAFEHPVALCDGVHVEIQRAVHRADVGALPRLAGNRPGHRRPAAAVTPQVLGGGDVYSVIPDPGTPVYPT
SNTTWVATPWSQTVQVTGNPYLALNYTDKNGGPHDCAIQVDGQAVALAEHKPGRREVVKREILVGVAVIAIVVASGAGCS
DKKSGAPDPGASAPAGPQLIVDGKNLNVSGPVRCTPSGNNVNIAVGDAATGIGAVVSKDDPPIVHAVGLGKVDGMTLGYS
DVAKGQAGNAGAAVSGKSLQIKGTANGADADRKLRTEAREGLHTMSITRLTAAAAVAAVLGMSASAATAGFAGSAPLNPA
PCPSWEKACSGGPPAPNNPGYGGTGSQPPIAPAPYSTQPAPSTYQPPRTPAAPPSTYQPPHTTAAPPSTYQPPHTTAAPP
NTYQPPHTTAAPPTSWQKPPVTSMPTASNCPNWEHDCTPTPSSPNSGYGGATPPSAPPTTAWQRQAPPNGPTTSMPVECA
SWYKSCTPTPNPGPGYGGVTSPATGAPWNGSSPPPGWNGQSPQPERSAYPTPTRPVLNAPWTQPPHPPYYPPPPPIPHPT
DQYGGPTNLATGGYWVPGQGAPPPPPPNSYGWSNGPAPGAPPPNWEGPPPSGGWNGPPPAGGWNQPWQGPPVDQSYGQNY
YAPFTCNNFTVLPVFNADYGGFGYWFFGVWLSRPSPPSVPGPRREARPTGSLHASGEGRLRAGARRRDVVPPVDHLDVRA
HDHRGVGARLAGVPVGRIDPSGGLVLLQRALAHVDRGDVVVAALFEHPVVLRGGVHVEVQRAVHRTDVGALPRPEVVRKA
VQGGPGPTPRSDGEVAAAIGGVTVERRAGLQLAAVVERNQRRGGVRGSERGWRRREHQTDACQRCDQPLHLEGDFDRIGL
RVRLARQDQAVVEVLLLQHVVDLHRHLAAAQSGGAGTAVALAAGERRVQAGVEQHVEQLRLTRPRHGVGLPVELDDSAGR
TLGFIIGVVVVNFDRGERVAVQRLEHLEMYVRCRHFQAFQRLASGRHERARPADERLALGERRGQSGQRRGRRQPLQRLE
PVHDGQPVRVLRRQLAQRVGEDHRPLVAVRIDQYHLPAALGQRRLADRHHRRDPAAGREQHEIIVKRLGYERARRRQHVD
PHTGVGVVAQPVRGVAIPVALDRDGHRLVGERRTAQRVAARHRPGAIARNAQREELSGGVAQPIRRYICAVRNSEHQRAG
VVGFGDDVGDLQLQNMAAEWLVGNCARHSPALPSVITRTGYRKMASLCLRKPPLEEAVTSIQQRDAQSVLDGIDELLPKL
RQRAQETEDLRRLPDATVSELQEIGFFRLLQPQQWGGLECDPAVFYEAVRRIGSACGSTGWVSSIIGVHNWHLALFDQQA
QDEVWGDDTNVRVSSSYAPMGAGTVVDGGYLVSGAWQWSSGCDHATWAFLGGPVIKDGRPVDFGSFLIPRSDYRIDDVWH
VVGLKGTGSNTVVVKDAFVPRHRFLSYKQMNDGTAGGYENNTAAVYKMPWGTMHPTTISAPIVGMAYGAYEAHVEHQGKR
VRAAFAGEKAKDDPFAKVRVAEAASDIDAAWRQLIGNVSDEYALLSEGKEIPFELRARARRDQVRATGRSIASVDRLFEA
SGATALASDAPVQRFWRDAHAGRVHAANDPERAYQIFGNHEFGLPPGDTMVDVDGPLKLHYHEAGVGNEQTIVLLHGGGP
GAASWTNFSRNIPVLAERFHVLAVDQPGYGHSDKRAEHAQFNHYAARALKGLFDHLGLGRVPLVGNSLGGGTAVRFALDY
PDNAGKLVLMGPGGLSINLFAPDPTEGVKRLGKFSVEPTRENLEAFLRVMVHNQKLITPELIDQRFELASTPESLTATRA
MGMSFAGADFELGMMWREVHKLRQPVLLIWGREDRVNPLDGALVALKTIPRAQLHVFGQCGHWAQAWRDYGLKVLGMVEG
KGSTEGALYLRMDDFPARLVIVPGEHDRLLESGWECANAEGLQEIRNRLDVEGTPYKEATAAELADRRVDEMIIFSDPSG
NGLEVFHGAALEHRRVVSPYGHKFVTAEQGLGHVVLTTRDDAETLHFYRDVLGFTLRDSMRLPPQVVGRPADGPPAWLRF
LGCNPRHHSLAFMPGQTPSGIVHLMIEVGEADDVGLCLDRALRRKVPMSATLGRHVNDLMLSFYMKTPGGFDVEFGCEGR
QIDARAFRSVLGQFCTGITIITTVHDDAPVGFACQSFAALSLDPPLVLFCPTKVSRSWQAIEASGKFCVNVLTESQQHVS
ARFGSKEPDKFAGIDWHASKLGSPIIDGSLAYIDCTVASVHDGGDHFVVFGAVQSLSEPPQIKPRPLLFYRGDYTGIEPD
KTRPAQWRDDLEAFLTTTTQDTWL