PlantSME Plant secondary metabolism enzyme database
Phenylpropanoid portable pathway

Phenylpropanoid portable pathway

Category：Phenylpropanoid pathway

Phenylpropanoid pathway definition imported from the 2026-05-17 portable BLAST/HMM package.

Representative Phenylpropanoid Reaction Route
Entry backbone to monolignol/lignin branches. Substrates, products, and condensed structural formulae show representative conversions; resolved reactions are shown as single enzymes, whereas multi-enzyme branches are shown as curated modules. Member counts come from public annotations.
6 curated steps/modules
Entry Backbone And Lignin Direction
01
Substrate
L-Phenylalanine
C9H11NO2
C6H5-CH2-CH(NH2)-COOH
Deamination to form the phenylpropene acid scaffold
PAL196
Product
trans-Cinnamic acid
C9H8O2
C6H5-CH=CH-COOH
PAL commits the amino-acid substrate to phenylpropanoid metabolism.
02
Substrate
trans-Cinnamic acid
C9H8O2
C6H5-CH=CH-COOH
Para-hydroxylation of the aromatic ring
C4H193
Product
p-Coumaric acid
C9H8O3
4-HO-C6H4-CH=CH-COOH
C4H/CYP73A introduces the 4-hydroxyl group for downstream CoA activation.
03
Substrate
p-Coumaric acid
C9H8O3
4-HO-C6H4-CH=CH-COOH
Substrate
CoA
C21H36N7O16P3S
CoA-SH
CoA ligation and activation
4CL771
Product
p-Coumaroyl-CoA
C30H38N7O18P3S
4-HO-C6H4-CH=CH-C(=O)-SCoA
4CL converts the free acid into a thioester used by condensation, acyltransfer, and reduction reactions.
04
Substrate
p-Coumaroyl-CoA
C30H38N7O18P3S
4-HO-C6H4-CH=CH-C(=O)-SCoA
Hydroxylation, acyl transfer, and methylation
HCT676 C3'H/CYP98A400 CSE681 CCoAOMT130
Product
Feruloyl-CoA-type intermediates
C31H40N7O19P3S
3-MeO-4-HO-C6H3-CH=CH-C(=O)-SCoA
This segment remodels the p-coumaroyl scaffold into caffeoyl/feruloyl-type intermediates.
05
Substrate
Hydroxycinnamoyl-CoA
C30-31 CoA thioesters
Ar-CH=CH-C(=O)-SCoA
Reduction and S/G monolignol formation
CCR505 CAD711 F5H/CYP84A83 COMT604
Product
Coniferyl/sinapyl alcohol
C10H12O3 / C11H14O4
Ar-CH=CH-CH2OH
CCR/CAD and related steps route CoA thioesters toward monolignol monomers.
06
Substrate
Monolignols
C9-C11 phenylpropanoids
Ar-CH=CH-CH2OH
Oxidative coupling and polymerization
LAC945 POD2554
Product
Lignin polymer
(C9 unit)n
[Ar-C3]n ether/C-C polymer
LAC/POD oxidatively couple monolignols into lignin polymers.
Lineage Distribution
Assignments under this module are distributed across the following plant lineages.
All Lineages Basal angiosperms (8449)
Current lineage filter: Basal angiosperms. All species, family, module, and gene statistics below have been narrowed to this lineage.
Algae
Hits0
Bryophytes
Hits0
Lycophytes/Ferns
Hits0
Gymnosperms
Hits0
Basal angiosperms
Hits8449
Monocots
Hits0
Eudicots
Hits0
Species Distribution
Brasenia schreberi
Annona cherimola
Cinnamomum kanehirae
Chloranthus sessilifolius
Amborella trichopoda
Aristolochia contorta
Cinnamomum camphora
Piper nigrum
Liriodendron chinense
Piper longum
Lineage Summary
Basal angiosperms
8449
Module Gene List
Reset
GeneSpeciesProtein ID
cinnamomum_camphora_GWHPBGXC010192 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC010192
cinnamomum_camphora_GWHPBGXC010195 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC010195
cinnamomum_camphora_GWHPBGXC010196 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC010196
cinnamomum_camphora_GWHPBGXC010276 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC010276
cinnamomum_camphora_GWHPBGXC010503 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC010503
cinnamomum_camphora_GWHPBGXC010667 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC010667
cinnamomum_camphora_GWHPBGXC010688 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC010688
cinnamomum_camphora_GWHPBGXC010700 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC010700
cinnamomum_camphora_GWHPBGXC010758 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC010758
cinnamomum_camphora_GWHPBGXC010826 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC010826
cinnamomum_camphora_GWHPBGXC010842 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC010842
cinnamomum_camphora_GWHPBGXC011029 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC011029
cinnamomum_camphora_GWHPBGXC011049 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC011049
cinnamomum_camphora_GWHPBGXC011150 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC011150
cinnamomum_camphora_GWHPBGXC011151 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC011151
cinnamomum_camphora_GWHPBGXC011200 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC011200
cinnamomum_camphora_GWHPBGXC011236 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC011236
cinnamomum_camphora_GWHPBGXC011337 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC011337
cinnamomum_camphora_GWHPBGXC011338 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC011338
cinnamomum_camphora_GWHPBGXC011339 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC011339
cinnamomum_camphora_GWHPBGXC011503 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC011503
cinnamomum_camphora_GWHPBGXC011514 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC011514
cinnamomum_camphora_GWHPBGXC011563 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC011563
cinnamomum_camphora_GWHPBGXC011569 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC011569
cinnamomum_camphora_GWHPBGXC011623 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC011623
cinnamomum_camphora_GWHPBGXC011624 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC011624
cinnamomum_camphora_GWHPBGXC011627 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC011627
cinnamomum_camphora_GWHPBGXC011628 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC011628
cinnamomum_camphora_GWHPBGXC011629 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC011629
cinnamomum_camphora_GWHPBGXC011630 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC011630