CAS

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family CAS.

Lineage Coverage

Detected in 783 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 35857 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
Alyrscaffold_30099750.1	arabidopsis_lyrata	Alyrscaffold_30099750.1
Alyrscaffold_30109300.1	arabidopsis_lyrata	Alyrscaffold_30109300.1
Alyrscaffold_30114170.1	arabidopsis_lyrata	Alyrscaffold_30114170.1
Alyrscaffold_30115730.1	arabidopsis_lyrata	Alyrscaffold_30115730.1
Alyrscaffold_40128220.1	arabidopsis_lyrata	Alyrscaffold_40128220.1
Alyrscaffold_40128880.1	arabidopsis_lyrata	Alyrscaffold_40128880.1
Alyrscaffold_40128890.1	arabidopsis_lyrata	Alyrscaffold_40128890.1
Alyrscaffold_40128900.1	arabidopsis_lyrata	Alyrscaffold_40128900.1
Alyrscaffold_40129380.1	arabidopsis_lyrata	Alyrscaffold_40129380.1
Alyrscaffold_40129390.1	arabidopsis_lyrata	Alyrscaffold_40129390.1
Alyrscaffold_40129390.2	arabidopsis_lyrata	Alyrscaffold_40129390.2
Alyrscaffold_40129410.1	arabidopsis_lyrata	Alyrscaffold_40129410.1
Alyrscaffold_40154800.1	arabidopsis_lyrata	Alyrscaffold_40154800.1
Alyrscaffold_50164620.1	arabidopsis_lyrata	Alyrscaffold_50164620.1
Alyrscaffold_50168680.1	arabidopsis_lyrata	Alyrscaffold_50168680.1
Alyrscaffold_50172210.1	arabidopsis_lyrata	Alyrscaffold_50172210.1
Alyrscaffold_50176780.1	arabidopsis_lyrata	Alyrscaffold_50176780.1
Alyrscaffold_50189200.1	arabidopsis_lyrata	Alyrscaffold_50189200.1
Alyrscaffold_50190990.1	arabidopsis_lyrata	Alyrscaffold_50190990.1
Alyrscaffold_60216960.1	arabidopsis_lyrata	Alyrscaffold_60216960.1
Alyrscaffold_60222410.1	arabidopsis_lyrata	Alyrscaffold_60222410.1
Alyrscaffold_60222440.1	arabidopsis_lyrata	Alyrscaffold_60222440.1
Alyrscaffold_60231070.1	arabidopsis_lyrata	Alyrscaffold_60231070.1
Alyrscaffold_70261540.1	arabidopsis_lyrata	Alyrscaffold_70261540.1
Alyrscaffold_70261570.1	arabidopsis_lyrata	Alyrscaffold_70261570.1
Alyrscaffold_70263650.1	arabidopsis_lyrata	Alyrscaffold_70263650.1
Alyrscaffold_70264280.1	arabidopsis_lyrata	Alyrscaffold_70264280.1
Alyrscaffold_80284250.1	arabidopsis_lyrata	Alyrscaffold_80284250.1
Alyrscaffold_80286180.1	arabidopsis_lyrata	Alyrscaffold_80286180.1
ara_suecica_KAG7538346.1	arabidopsis_suecica	ara_suecica_KAG7538346.1