CAS

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family CAS.

Lineage Coverage

Detected in 783 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 35857 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
Aalbaalba5_s000296170164300.1	abies_alba	Aalbaalba5_s000296170164300.1
Aalbaalba5_s004122830789840.1	abies_alba	Aalbaalba5_s004122830789840.1
XP_027335147.1	abrus_precatorius	XP_027335147.1
XP_027338614.1	abrus_precatorius	XP_027338614.1
XP_027342505.1	abrus_precatorius	XP_027342505.1
XP_027342506.1	abrus_precatorius	XP_027342506.1
XP_027343009.1	abrus_precatorius	XP_027343009.1
XP_027343010.1	abrus_precatorius	XP_027343010.1
XP_027343013.1	abrus_precatorius	XP_027343013.1
XP_027344009.1	abrus_precatorius	XP_027344009.1
XP_027347337.1	abrus_precatorius	XP_027347337.1
XP_027348218.1	abrus_precatorius	XP_027348218.1
XP_027348219.1	abrus_precatorius	XP_027348219.1
XP_027348360.1	abrus_precatorius	XP_027348360.1
XP_027351053.1	abrus_precatorius	XP_027351053.1
XP_027351676.1	abrus_precatorius	XP_027351676.1
XP_027353994.1	abrus_precatorius	XP_027353994.1
XP_027353995.1	abrus_precatorius	XP_027353995.1
XP_027353997.1	abrus_precatorius	XP_027353997.1
XP_027353998.1	abrus_precatorius	XP_027353998.1
XP_027354358.1	abrus_precatorius	XP_027354358.1
XP_027354469.1	abrus_precatorius	XP_027354469.1
XP_027355217.1	abrus_precatorius	XP_027355217.1
XP_027355362.1	abrus_precatorius	XP_027355362.1
XP_027355363.1	abrus_precatorius	XP_027355363.1
XP_027355658.1	abrus_precatorius	XP_027355658.1
XP_027355929.1	abrus_precatorius	XP_027355929.1
XP_027355930.1	abrus_precatorius	XP_027355930.1
XP_027355931.1	abrus_precatorius	XP_027355931.1
XP_027355932.1	abrus_precatorius	XP_027355932.1