CAS

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family CAS.

Lineage Coverage

Detected in 783 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 35857 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
XP_027355933.1	abrus_precatorius	XP_027355933.1
XP_027356304.1	abrus_precatorius	XP_027356304.1
XP_027356305.1	abrus_precatorius	XP_027356305.1
XP_027356306.1	abrus_precatorius	XP_027356306.1
XP_027356547.1	abrus_precatorius	XP_027356547.1
XP_027356548.1	abrus_precatorius	XP_027356548.1
XP_027356549.1	abrus_precatorius	XP_027356549.1
XP_027356551.1	abrus_precatorius	XP_027356551.1
XP_027356552.1	abrus_precatorius	XP_027356552.1
XP_027356563.1	abrus_precatorius	XP_027356563.1
XP_027356564.1	abrus_precatorius	XP_027356564.1
XP_027356565.1	abrus_precatorius	XP_027356565.1
XP_027356567.1	abrus_precatorius	XP_027356567.1
XP_027356568.1	abrus_precatorius	XP_027356568.1
XP_027363290.1	abrus_precatorius	XP_027363290.1
Aalbaalba5_s000043180034700.1	abies_alba	Aalbaalba5_s000043180034700.1
Aalbaalba5_s000058300044450.1	abies_alba	Aalbaalba5_s000058300044450.1
Aalbaalba5_s000058300044450.2	abies_alba	Aalbaalba5_s000058300044450.2
Aalbaalba5_s000084450061020.1	abies_alba	Aalbaalba5_s000084450061020.1
Aalbaalba5_s000253850146550.1	abies_alba	Aalbaalba5_s000253850146550.1
Aalbaalba5_s000263920151170.1	abies_alba	Aalbaalba5_s000263920151170.1
Aalbaalba5_s000356730190580.1	abies_alba	Aalbaalba5_s000356730190580.1
Aalbaalba5_s000446870229430.1	abies_alba	Aalbaalba5_s000446870229430.1
Aalbaalba5_s000446870229430.2	abies_alba	Aalbaalba5_s000446870229430.2
Aalbaalba5_s000446870229430.3	abies_alba	Aalbaalba5_s000446870229430.3
Aalbaalba5_s000637730298960.1	abies_alba	Aalbaalba5_s000637730298960.1
Aalbaalba5_s000715010322940.1	abies_alba	Aalbaalba5_s000715010322940.1
Aalbaalba5_s000801480349180.1	abies_alba	Aalbaalba5_s000801480349180.1
Aalbaalba5_s000923950383350.1	abies_alba	Aalbaalba5_s000923950383350.1
Aalbaalba5_s000931670385360.1	abies_alba	Aalbaalba5_s000931670385360.1