CAS

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family CAS.

Lineage Coverage

Detected in 783 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 35857 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
actinidia_hemsleyana_GWHPCBQA026106	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA026106
actinidia_hemsleyana_GWHPCBQA026712	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA026712
actinidia_hemsleyana_GWHPCBQA026714	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA026714
actinidia_hemsleyana_GWHPCBQA026715	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA026715
actinidia_hemsleyana_GWHPCBQA027884	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA027884
actinidia_hemsleyana_GWHPCBQA027885	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA027885
actinidia_hemsleyana_GWHPCBQA028363	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA028363
actinidia_hemsleyana_GWHPCBQA028364	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA028364
actinidia_hemsleyana_GWHPCBQA028590	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA028590
actinidia_hemsleyana_GWHPCBQA029448	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA029448
actinidia_hemsleyana_GWHPCBQA030264	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA030264
actinidia_hemsleyana_GWHPCBQA031292	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA031292
actinidia_hemsleyana_GWHPCBQA031294	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA031294
actinidia_hemsleyana_GWHPCBQA031295	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA031295
actinidia_hemsleyana_GWHPCBQA031845	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA031845
actinidia_hemsleyana_GWHPCBQA031846	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA031846
actinidia_hemsleyana_GWHPCBQA034832	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA034832
actinidia_hemsleyana_GWHPCBQA035056	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA035056
actinidia_hemsleyana_GWHPCBQA035057	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA035057
actinidia_hemsleyana_GWHPCBQA035555	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA035555
actinidia_hemsleyana_GWHPCBQA036251	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA036251
actinidia_hemsleyana_GWHPCBQA036993	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA036993
actinidia_hemsleyana_GWHPCBQA038018	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA038018
actinidia_hemsleyana_GWHPCBQA043971	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA043971
actinidia_hemsleyana_GWHPCBQA045259	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA045259
actinidia_hemsleyana_GWHPCBQA045260	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA045260
actinidia_hemsleyana_GWHPCBQA045263	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA045263
actinidia_hemsleyana_GWHPCBQA045264	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA045264
actinidia_hemsleyana_GWHPCBQA046529	actinidia_hemsleyana	actinidia_hemsleyana_GWHPCBQA046529
actinidia_zhejiangensis_GWHPCBQB000501	actinidia_zhejiangensis	actinidia_zhejiangensis_GWHPCBQB000501