CAS

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family CAS.

Lineage Coverage

Detected in 783 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 35857 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
AeveUnknownG0010790.1	aeschynomene_evenia	AeveUnknownG0010790.1
AaraAA_scaffold10460055780	aethionema_arabicum	AaraAA_scaffold10460055780
AaraAA_scaffold12180070100	aethionema_arabicum	AaraAA_scaffold12180070100
AaraAA_scaffold12180070120	aethionema_arabicum	AaraAA_scaffold12180070120
AaraAA_scaffold14530079950	aethionema_arabicum	AaraAA_scaffold14530079950
AaraAA_scaffold16840090840	aethionema_arabicum	AaraAA_scaffold16840090840
AaraAA_scaffold22600120920	aethionema_arabicum	AaraAA_scaffold22600120920
AaraAA_scaffold22600120930	aethionema_arabicum	AaraAA_scaffold22600120930
AaraAA_scaffold2290123240	aethionema_arabicum	AaraAA_scaffold2290123240
AaraAA_scaffold23300126600	aethionema_arabicum	AaraAA_scaffold23300126600
AaraAA_scaffold23300126610	aethionema_arabicum	AaraAA_scaffold23300126610
AaraAA_scaffold23550127280	aethionema_arabicum	AaraAA_scaffold23550127280
AaraAA_scaffold24010130270	aethionema_arabicum	AaraAA_scaffold24010130270
AaraAA_scaffold25030134680	aethionema_arabicum	AaraAA_scaffold25030134680
AaraAA_scaffold25350139200	aethionema_arabicum	AaraAA_scaffold25350139200
AaraAA_scaffold2920155260	aethionema_arabicum	AaraAA_scaffold2920155260
AaraAA_scaffold2920155270	aethionema_arabicum	AaraAA_scaffold2920155270
AaraAA_scaffold3320168650	aethionema_arabicum	AaraAA_scaffold3320168650
AaraAA_scaffold33370169330	aethionema_arabicum	AaraAA_scaffold33370169330
AaraAA_scaffold35930186830	aethionema_arabicum	AaraAA_scaffold35930186830
AaraAA_scaffold36760191390	aethionema_arabicum	AaraAA_scaffold36760191390
AaraAA_scaffold39530203400	aethionema_arabicum	AaraAA_scaffold39530203400
AaraAA_scaffold5170261560	aethionema_arabicum	AaraAA_scaffold5170261560
AaraAA_scaffold52400265760	aethionema_arabicum	AaraAA_scaffold52400265760
AaraAA_scaffold53540271550	aethionema_arabicum	AaraAA_scaffold53540271550
AaraAA_scaffold53620271990	aethionema_arabicum	AaraAA_scaffold53620271990
AaraAA_scaffold55900285480	aethionema_arabicum	AaraAA_scaffold55900285480
AaraAA_scaffold5780302360	aethionema_arabicum	AaraAA_scaffold5780302360
AaraAA_scaffold5780302390	aethionema_arabicum	AaraAA_scaffold5780302390
AaraAA_scaffold60660319160	aethionema_arabicum	AaraAA_scaffold60660319160