CAS

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family CAS.

Lineage Coverage

Detected in 783 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 35857 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
Avestig00002108_pilon0167630.1	aldrovanda_vesiculosa	Avestig00002108_pilon0167630.1
Avestig00010553_pilon0189430.1	aldrovanda_vesiculosa	Avestig00010553_pilon0189430.1
Avestig00010586_pilon0209200.1	aldrovanda_vesiculosa	Avestig00010586_pilon0209200.1
Avestig00010620_pilon0220800.1	aldrovanda_vesiculosa	Avestig00010620_pilon0220800.1
Avestig00010791_pilon0238460.1	aldrovanda_vesiculosa	Avestig00010791_pilon0238460.1
Avestig00011008_pilon0246060.1	aldrovanda_vesiculosa	Avestig00011008_pilon0246060.1
Agluscaffold10168_cov850002710	alnus_glutinosa	Agluscaffold10168_cov850002710
Agluscaffold10314_cov970005470	alnus_glutinosa	Agluscaffold10314_cov970005470
Agluscaffold10396_cov1050007630	alnus_glutinosa	Agluscaffold10396_cov1050007630
Agluscaffold10396_cov1050007640	alnus_glutinosa	Agluscaffold10396_cov1050007640
Agluscaffold10410_cov1030008770	alnus_glutinosa	Agluscaffold10410_cov1030008770
Agluscaffold106391_cov960013110	alnus_glutinosa	Agluscaffold106391_cov960013110
Agluscaffold1126_cov630022410	alnus_glutinosa	Agluscaffold1126_cov630022410
Agluscaffold11341_cov990023180	alnus_glutinosa	Agluscaffold11341_cov990023180
Agluscaffold11470_cov770024410	alnus_glutinosa	Agluscaffold11470_cov770024410
Agluscaffold11556_cov920025430	alnus_glutinosa	Agluscaffold11556_cov920025430
Agluscaffold1193_cov960031640	alnus_glutinosa	Agluscaffold1193_cov960031640
Agluscaffold126020_cov510040020	alnus_glutinosa	Agluscaffold126020_cov510040020
Agluscaffold12940_cov580044030	alnus_glutinosa	Agluscaffold12940_cov580044030
Agluscaffold1312_cov740047020	alnus_glutinosa	Agluscaffold1312_cov740047020
Agluscaffold1312_cov740047040	alnus_glutinosa	Agluscaffold1312_cov740047040
Agluscaffold14870_cov890068270	alnus_glutinosa	Agluscaffold14870_cov890068270
Agluscaffold14870_cov890068310	alnus_glutinosa	Agluscaffold14870_cov890068310
Agluscaffold15922_cov1020078880	alnus_glutinosa	Agluscaffold15922_cov1020078880
Agluscaffold16388_cov840084400	alnus_glutinosa	Agluscaffold16388_cov840084400
Agluscaffold16455_cov990084990	alnus_glutinosa	Agluscaffold16455_cov990084990
Agluscaffold1691_cov680088640	alnus_glutinosa	Agluscaffold1691_cov680088640
Agluscaffold17508_cov900093710	alnus_glutinosa	Agluscaffold17508_cov900093710
Agluscaffold17508_cov900093730	alnus_glutinosa	Agluscaffold17508_cov900093730
Agluscaffold19389_cov910111360	alnus_glutinosa	Agluscaffold19389_cov910111360