CAS

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family CAS.

Lineage Coverage

Detected in 783 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 35857 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
alnus_rubra_ALNRU00054264-RA	alnus_rubra	alnus_rubra_ALNRU00054264-RA
alnus_rubra_ALNRU00054265-RA	alnus_rubra	alnus_rubra_ALNRU00054265-RA
alnus_rubra_ALNRU00054907-RA	alnus_rubra	alnus_rubra_ALNRU00054907-RA
alnus_rubra_ALNRU00059967-RA	alnus_rubra	alnus_rubra_ALNRU00059967-RA
alnus_rubra_ALNRU00065532-RA	alnus_rubra	alnus_rubra_ALNRU00065532-RA
alnus_rubra_ALNRU00065547-RA	alnus_rubra	alnus_rubra_ALNRU00065547-RA
alnus_rubra_ALNRU00065552-RA	alnus_rubra	alnus_rubra_ALNRU00065552-RA
alnus_rubra_ALNRU00065557-RA	alnus_rubra	alnus_rubra_ALNRU00065557-RA
alnus_rubra_ALNRU00065573-RA	alnus_rubra	alnus_rubra_ALNRU00065573-RA
alnus_rubra_ALNRU00065577-RA	alnus_rubra	alnus_rubra_ALNRU00065577-RA
alnus_rubra_ALNRU00065580-RA	alnus_rubra	alnus_rubra_ALNRU00065580-RA
alnus_rubra_ALNRU00065583-RA	alnus_rubra	alnus_rubra_ALNRU00065583-RA
alnus_rubra_ALNRU00065588-RA	alnus_rubra	alnus_rubra_ALNRU00065588-RA
alnus_rubra_ALNRU00080958-RA	alnus_rubra	alnus_rubra_ALNRU00080958-RA
alnus_rubra_ALNRU00086385-RA	alnus_rubra	alnus_rubra_ALNRU00086385-RA
alnus_rubra_ALNRU00086532-RA	alnus_rubra	alnus_rubra_ALNRU00086532-RA
alnus_rubra_ALNRU00088130-RA	alnus_rubra	alnus_rubra_ALNRU00088130-RA
alnus_rubra_ALNRU00088131-RA	alnus_rubra	alnus_rubra_ALNRU00088131-RA
alnus_rubra_ALNRU00088135-RA	alnus_rubra	alnus_rubra_ALNRU00088135-RA
alnus_rubra_ALNRU00093415-RA	alnus_rubra	alnus_rubra_ALNRU00093415-RA
alnus_rubra_ALNRU00093417-RA	alnus_rubra	alnus_rubra_ALNRU00093417-RA
alnus_rubra_ALNRU00093419-RA	alnus_rubra	alnus_rubra_ALNRU00093419-RA
alnus_rubra_ALNRU00093424-RA	alnus_rubra	alnus_rubra_ALNRU00093424-RA
alnus_rubra_ALNRU00093435-RA	alnus_rubra	alnus_rubra_ALNRU00093435-RA
alnus_rubra_ALNRU00093447-RA	alnus_rubra	alnus_rubra_ALNRU00093447-RA
alnus_rubra_ALNRU00093451-RA	alnus_rubra	alnus_rubra_ALNRU00093451-RA
alnus_rubra_ALNRU00096030-RA	alnus_rubra	alnus_rubra_ALNRU00096030-RA
alnus_rubra_ALNRU00096034-RA	alnus_rubra	alnus_rubra_ALNRU00096034-RA
alnus_rubra_ALNRU00096044-RA	alnus_rubra	alnus_rubra_ALNRU00096044-RA
alnus_rubra_ALNRU00096053-RA	alnus_rubra	alnus_rubra_ALNRU00096053-RA