CAS

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family CAS.

Lineage Coverage

Detected in 783 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 35857 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
alnus_rubra_ALNRU00125577-RA	alnus_rubra	alnus_rubra_ALNRU00125577-RA
alnus_rubra_ALNRU00125801-RA	alnus_rubra	alnus_rubra_ALNRU00125801-RA
alnus_rubra_ALNRU00126624-RA	alnus_rubra	alnus_rubra_ALNRU00126624-RA
alnus_rubra_ALNRU00127552-RA	alnus_rubra	alnus_rubra_ALNRU00127552-RA
alnus_rubra_ALNRU00130069-RA	alnus_rubra	alnus_rubra_ALNRU00130069-RA
alnus_rubra_ALNRU00131799-RA	alnus_rubra	alnus_rubra_ALNRU00131799-RA
alnus_rubra_ALNRU00131807-RA	alnus_rubra	alnus_rubra_ALNRU00131807-RA
alnus_rubra_ALNRU00134064-RA	alnus_rubra	alnus_rubra_ALNRU00134064-RA
alnus_rubra_ALNRU00138061-RA	alnus_rubra	alnus_rubra_ALNRU00138061-RA
alnus_rubra_ALNRU00139679-RA	alnus_rubra	alnus_rubra_ALNRU00139679-RA
alnus_rubra_ALNRU00140457-RA	alnus_rubra	alnus_rubra_ALNRU00140457-RA
alnus_rubra_ALNRU00141030-RA	alnus_rubra	alnus_rubra_ALNRU00141030-RA
alstonia_scholaris_tjs01229	alstonia_scholaris	alstonia_scholaris_tjs01229
alstonia_scholaris_tjs03085	alstonia_scholaris	alstonia_scholaris_tjs03085
alstonia_scholaris_tjs03361	alstonia_scholaris	alstonia_scholaris_tjs03361
alstonia_scholaris_tjs04395	alstonia_scholaris	alstonia_scholaris_tjs04395
alstonia_scholaris_tjs05109	alstonia_scholaris	alstonia_scholaris_tjs05109
alstonia_scholaris_tjs05754	alstonia_scholaris	alstonia_scholaris_tjs05754
alstonia_scholaris_tjs06100	alstonia_scholaris	alstonia_scholaris_tjs06100
alstonia_scholaris_tjs06978	alstonia_scholaris	alstonia_scholaris_tjs06978
alstonia_scholaris_tjs07889	alstonia_scholaris	alstonia_scholaris_tjs07889
alstonia_scholaris_tjs08095	alstonia_scholaris	alstonia_scholaris_tjs08095
alstonia_scholaris_tjs08403	alstonia_scholaris	alstonia_scholaris_tjs08403
alstonia_scholaris_tjs09425	alstonia_scholaris	alstonia_scholaris_tjs09425
alstonia_scholaris_tjs09426	alstonia_scholaris	alstonia_scholaris_tjs09426
alstonia_scholaris_tjs09977	alstonia_scholaris	alstonia_scholaris_tjs09977
alstonia_scholaris_tjs10324	alstonia_scholaris	alstonia_scholaris_tjs10324
alstonia_scholaris_tjs12426	alstonia_scholaris	alstonia_scholaris_tjs12426
alstonia_scholaris_tjs12690	alstonia_scholaris	alstonia_scholaris_tjs12690
alstonia_scholaris_tjs12705	alstonia_scholaris	alstonia_scholaris_tjs12705