CAS

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family CAS.

Lineage Coverage

Detected in 783 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 35857 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
alstonia_scholaris_tjs37581	alstonia_scholaris	alstonia_scholaris_tjs37581
AcruScioBoG_102837_HRSCAF_1030740033520.1	amaranthus_cruentus	AcruScioBoG_102837_HRSCAF_1030740033520.1
AcruScioBoG_102838_HRSCAF_1030810040050.1	amaranthus_cruentus	AcruScioBoG_102838_HRSCAF_1030810040050.1
AcruScioBoG_102839_HRSCAF_1030930049450.1	amaranthus_cruentus	AcruScioBoG_102839_HRSCAF_1030930049450.1
AcruScioBoG_102839_HRSCAF_1030930049450.2	amaranthus_cruentus	AcruScioBoG_102839_HRSCAF_1030930049450.2
AcruScioBoG_102839_HRSCAF_1030930049450.3	amaranthus_cruentus	AcruScioBoG_102839_HRSCAF_1030930049450.3
AcruScioBoG_102839_HRSCAF_1030930049450.4	amaranthus_cruentus	AcruScioBoG_102839_HRSCAF_1030930049450.4
AcruScioBoG_102840_HRSCAF_1030990059540.1	amaranthus_cruentus	AcruScioBoG_102840_HRSCAF_1030990059540.1
AcruScioBoG_102840_HRSCAF_1030990059540.2	amaranthus_cruentus	AcruScioBoG_102840_HRSCAF_1030990059540.2
AcruScioBoG_102840_HRSCAF_1030990059550.1	amaranthus_cruentus	AcruScioBoG_102840_HRSCAF_1030990059550.1
AcruScioBoG_102840_HRSCAF_1030990061520.1	amaranthus_cruentus	AcruScioBoG_102840_HRSCAF_1030990061520.1
AcruScioBoG_102840_HRSCAF_1030990061530.1	amaranthus_cruentus	AcruScioBoG_102840_HRSCAF_1030990061530.1
AcruScioBoG_102840_HRSCAF_1030990061530.2	amaranthus_cruentus	AcruScioBoG_102840_HRSCAF_1030990061530.2
AcruScioBoG_102840_HRSCAF_1030990061540.1	amaranthus_cruentus	AcruScioBoG_102840_HRSCAF_1030990061540.1
AcruScioBoG_102840_HRSCAF_1030990061540.2	amaranthus_cruentus	AcruScioBoG_102840_HRSCAF_1030990061540.2
AcruScioBoG_102840_HRSCAF_1030990061540.3	amaranthus_cruentus	AcruScioBoG_102840_HRSCAF_1030990061540.3
AcruScioBoG_12795_HRSCAF_128480079110.1	amaranthus_cruentus	AcruScioBoG_12795_HRSCAF_128480079110.1
AcruScioBoG_12795_HRSCAF_128480082380.1	amaranthus_cruentus	AcruScioBoG_12795_HRSCAF_128480082380.1
AcruScioBoG_13798_HRSCAF_138620086370.1	amaranthus_cruentus	AcruScioBoG_13798_HRSCAF_138620086370.1
AcruScioBoG_13798_HRSCAF_138620086370.2	amaranthus_cruentus	AcruScioBoG_13798_HRSCAF_138620086370.2
AcruScioBoG_13798_HRSCAF_138620086370.3	amaranthus_cruentus	AcruScioBoG_13798_HRSCAF_138620086370.3
AcruScioBoG_17730_HRSCAF_178110103570.1	amaranthus_cruentus	AcruScioBoG_17730_HRSCAF_178110103570.1
AcruScioBoG_19538_HRSCAF_196260123530.1	amaranthus_cruentus	AcruScioBoG_19538_HRSCAF_196260123530.1
AcruScioBoG_19538_HRSCAF_196260132560.1	amaranthus_cruentus	AcruScioBoG_19538_HRSCAF_196260132560.1
AcruScioBoG_19538_HRSCAF_196260132560.2	amaranthus_cruentus	AcruScioBoG_19538_HRSCAF_196260132560.2
AcruScioBoG_19538_HRSCAF_196260132560.3	amaranthus_cruentus	AcruScioBoG_19538_HRSCAF_196260132560.3
AcruScioBoG_19538_HRSCAF_196260132560.4	amaranthus_cruentus	AcruScioBoG_19538_HRSCAF_196260132560.4
AcruScioBoG_19538_HRSCAF_196260133880.1	amaranthus_cruentus	AcruScioBoG_19538_HRSCAF_196260133880.1
AcruScioBoG_19538_HRSCAF_196260134650.1	amaranthus_cruentus	AcruScioBoG_19538_HRSCAF_196260134650.1
AcruScioBoG_19743_HRSCAF_198340142350.1	amaranthus_cruentus	AcruScioBoG_19743_HRSCAF_198340142350.1