CAS

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family CAS.

Lineage Coverage

Detected in 783 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 35857 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
AMhypScaffold_80212500.1	amaranthus_hypochondriacus	AMhypScaffold_80212500.1
AMhypScaffold_80220610.1	amaranthus_hypochondriacus	AMhypScaffold_80220610.1
AMhypScaffold_80220620.1	amaranthus_hypochondriacus	AMhypScaffold_80220620.1
AMhypScaffold_80220650.1	amaranthus_hypochondriacus	AMhypScaffold_80220650.1
AMhypScaffold_80220660.1	amaranthus_hypochondriacus	AMhypScaffold_80220660.1
AMhypScaffold_80220690.1	amaranthus_hypochondriacus	AMhypScaffold_80220690.1
AMhypScaffold_90237460.1	amaranthus_hypochondriacus	AMhypScaffold_90237460.1
AMhypScaffold_90237470.1	amaranthus_hypochondriacus	AMhypScaffold_90237470.1
AMhypScaffold_90237500.1	amaranthus_hypochondriacus	AMhypScaffold_90237500.1
MAKER_01673-RA	amaranthus_palmeri	MAKER_01673-RA
MAKER_01860-RA	amaranthus_palmeri	MAKER_01860-RA
MAKER_03628-RA	amaranthus_palmeri	MAKER_03628-RA
MAKER_03946-RA	amaranthus_palmeri	MAKER_03946-RA
MAKER_09300-RA	amaranthus_palmeri	MAKER_09300-RA
MAKER_10796-RA	amaranthus_palmeri	MAKER_10796-RA
MAKER_12407-RA	amaranthus_palmeri	MAKER_12407-RA
MAKER_12408-RA	amaranthus_palmeri	MAKER_12408-RA
MAKER_13267-RA	amaranthus_palmeri	MAKER_13267-RA
MAKER_13470-RA	amaranthus_palmeri	MAKER_13470-RA
MAKER_14009-RA	amaranthus_palmeri	MAKER_14009-RA
MAKER_15429-RA	amaranthus_palmeri	MAKER_15429-RA
MAKER_17621-RA	amaranthus_palmeri	MAKER_17621-RA
MAKER_17623-RA	amaranthus_palmeri	MAKER_17623-RA
MAKER_17624-RA	amaranthus_palmeri	MAKER_17624-RA
MAKER_17882-RA	amaranthus_palmeri	MAKER_17882-RA
MAKER_18384-RA	amaranthus_palmeri	MAKER_18384-RA
MAKER_19059-RA	amaranthus_palmeri	MAKER_19059-RA
MAKER_19060-RA	amaranthus_palmeri	MAKER_19060-RA
MAKER_19061-RA	amaranthus_palmeri	MAKER_19061-RA
MAKER_19072-RA	amaranthus_palmeri	MAKER_19072-RA