CAS

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family CAS.

Lineage Coverage

Detected in 783 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 35857 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
Awil2620065260	andreaea_wilsonii	Awil2620065260
Awil2870068620	andreaea_wilsonii	Awil2870068620
Awil3601390097700	andreaea_wilsonii	Awil3601390097700
Awil3601400097730	andreaea_wilsonii	Awil3601400097730
Awil3780106400	andreaea_wilsonii	Awil3780106400
Awil8520145580	andreaea_wilsonii	Awil8520145580
Awil8620146510	andreaea_wilsonii	Awil8620146510
Amac1522040036620	andreaeobryum_macrosporum	Amac1522040036620
Amac1574090050570	andreaeobryum_macrosporum	Amac1574090050570
Amac1584420053640	andreaeobryum_macrosporum	Amac1584420053640
Amac1590760057510	andreaeobryum_macrosporum	Amac1590760057510
Amac1659030088370	andreaeobryum_macrosporum	Amac1659030088370
Amac1670480099720	andreaeobryum_macrosporum	Amac1670480099720
Amac1671190100590	andreaeobryum_macrosporum	Amac1671190100590
Amac976760144860	andreaeobryum_macrosporum	Amac976760144860
andrographis_paniculata_XP_051113919.1	andrographis_paniculata	andrographis_paniculata_XP_051113919.1
andrographis_paniculata_XP_051113920.1	andrographis_paniculata	andrographis_paniculata_XP_051113920.1
andrographis_paniculata_XP_051113921.1	andrographis_paniculata	andrographis_paniculata_XP_051113921.1
andrographis_paniculata_XP_051113922.1	andrographis_paniculata	andrographis_paniculata_XP_051113922.1
andrographis_paniculata_XP_051113924.1	andrographis_paniculata	andrographis_paniculata_XP_051113924.1
andrographis_paniculata_XP_051113925.1	andrographis_paniculata	andrographis_paniculata_XP_051113925.1
andrographis_paniculata_XP_051113926.1	andrographis_paniculata	andrographis_paniculata_XP_051113926.1
andrographis_paniculata_XP_051113927.1	andrographis_paniculata	andrographis_paniculata_XP_051113927.1
andrographis_paniculata_XP_051113928.1	andrographis_paniculata	andrographis_paniculata_XP_051113928.1
andrographis_paniculata_XP_051113929.1	andrographis_paniculata	andrographis_paniculata_XP_051113929.1
andrographis_paniculata_XP_051113930.1	andrographis_paniculata	andrographis_paniculata_XP_051113930.1
andrographis_paniculata_XP_051113931.1	andrographis_paniculata	andrographis_paniculata_XP_051113931.1
andrographis_paniculata_XP_051113932.1	andrographis_paniculata	andrographis_paniculata_XP_051113932.1
andrographis_paniculata_XP_051113933.1	andrographis_paniculata	andrographis_paniculata_XP_051113933.1
andrographis_paniculata_XP_051113934.1	andrographis_paniculata	andrographis_paniculata_XP_051113934.1