PlantSME Plant secondary metabolism enzyme database
DFR

DFR

Dihydroflavonol 4-reductase reference family.

Lineage Coverage
Detected in 484 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Diospyros kaki
Aegilops tauschii
Hordeum vulgare
Triticum aestivum
Related Modules
Flavonoid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Flavonoid pathway 1310 current-family members Mao et al. 2025; Gulzar et al. 2024; Vogt 2010
Phenylpropanoid entry
PAL 7015 C4H 464 4CL 25907
Flavonoid scaffold formation
CHS 11738 CHI 3089
Flavone and isoflavonoid branches
FNS 359 IFS 541 IFR 11814
Dihydroflavonol branches
F3H 4697 F3'H/CYP75B 1332 F3'5'H/CYP75A 247 FLS 124
Anthocyanin and proanthocyanidin branches
DFR 1310 ANS/LDOX 1019 UFGT 106747 ANR 1183
Family Gene List
GeneSpeciesProtein ID
andrographis_paniculata_XP_051119550.1 andrographis_paniculata andrographis_paniculata_XP_051119550.1
andrographis_paniculata_XP_051120187.1 andrographis_paniculata andrographis_paniculata_XP_051120187.1
andrographis_paniculata_XP_051120570.1 andrographis_paniculata andrographis_paniculata_XP_051120570.1
andrographis_paniculata_XP_051120614.1 andrographis_paniculata andrographis_paniculata_XP_051120614.1
andrographis_paniculata_XP_051121141.1 andrographis_paniculata andrographis_paniculata_XP_051121141.1
andrographis_paniculata_XP_051122195.1 andrographis_paniculata andrographis_paniculata_XP_051122195.1
andrographis_paniculata_XP_051122196.1 andrographis_paniculata andrographis_paniculata_XP_051122196.1
andrographis_paniculata_XP_051122197.1 andrographis_paniculata andrographis_paniculata_XP_051122197.1
andrographis_paniculata_XP_051122198.1 andrographis_paniculata andrographis_paniculata_XP_051122198.1
andrographis_paniculata_XP_051122432.1 andrographis_paniculata andrographis_paniculata_XP_051122432.1
andrographis_paniculata_XP_051122439.1 andrographis_paniculata andrographis_paniculata_XP_051122439.1
andrographis_paniculata_XP_051122448.1 andrographis_paniculata andrographis_paniculata_XP_051122448.1
andrographis_paniculata_XP_051122461.1 andrographis_paniculata andrographis_paniculata_XP_051122461.1
andrographis_paniculata_XP_051123430.1 andrographis_paniculata andrographis_paniculata_XP_051123430.1
andrographis_paniculata_XP_051123639.1 andrographis_paniculata andrographis_paniculata_XP_051123639.1
andrographis_paniculata_XP_051124257.1 andrographis_paniculata andrographis_paniculata_XP_051124257.1
andrographis_paniculata_XP_051124258.1 andrographis_paniculata andrographis_paniculata_XP_051124258.1
andrographis_paniculata_XP_051124424.1 andrographis_paniculata andrographis_paniculata_XP_051124424.1
andrographis_paniculata_XP_051127148.1 andrographis_paniculata andrographis_paniculata_XP_051127148.1
andrographis_paniculata_XP_051127155.1 andrographis_paniculata andrographis_paniculata_XP_051127155.1
andrographis_paniculata_XP_051127883.1 andrographis_paniculata andrographis_paniculata_XP_051127883.1
andrographis_paniculata_XP_051128664.1 andrographis_paniculata andrographis_paniculata_XP_051128664.1
andrographis_paniculata_XP_051129977.1 andrographis_paniculata andrographis_paniculata_XP_051129977.1
andrographis_paniculata_XP_051129978.1 andrographis_paniculata andrographis_paniculata_XP_051129978.1
andrographis_paniculata_XP_051130164.1 andrographis_paniculata andrographis_paniculata_XP_051130164.1
andrographis_paniculata_XP_051130407.1 andrographis_paniculata andrographis_paniculata_XP_051130407.1
andrographis_paniculata_XP_051130799.1 andrographis_paniculata andrographis_paniculata_XP_051130799.1
andrographis_paniculata_XP_051131456.1 andrographis_paniculata andrographis_paniculata_XP_051131456.1
andrographis_paniculata_XP_051131457.1 andrographis_paniculata andrographis_paniculata_XP_051131457.1
andrographis_paniculata_XP_051131458.1 andrographis_paniculata andrographis_paniculata_XP_051131458.1