PlantSME Plant secondary metabolism enzyme database
DFR

DFR

Dihydroflavonol 4-reductase reference family.

Lineage Coverage
Detected in 484 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Diospyros kaki
Aegilops tauschii
Hordeum vulgare
Triticum aestivum
Related Modules
Flavonoid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Flavonoid pathway 1310 current-family members Mao et al. 2025; Gulzar et al. 2024; Vogt 2010
Phenylpropanoid entry
PAL 7015 C4H 464 4CL 25907
Flavonoid scaffold formation
CHS 11738 CHI 3089
Flavone and isoflavonoid branches
FNS 359 IFS 541 IFR 11814
Dihydroflavonol branches
F3H 4697 F3'H/CYP75B 1332 F3'5'H/CYP75A 247 FLS 124
Anthocyanin and proanthocyanidin branches
DFR 1310 ANS/LDOX 1019 UFGT 106747 ANR 1183
Family Gene List
GeneSpeciesProtein ID
andrographis_paniculata_XP_051131459.1 andrographis_paniculata andrographis_paniculata_XP_051131459.1
andrographis_paniculata_XP_051131460.1 andrographis_paniculata andrographis_paniculata_XP_051131460.1
andrographis_paniculata_XP_051133007.1 andrographis_paniculata andrographis_paniculata_XP_051133007.1
andrographis_paniculata_XP_051133008.1 andrographis_paniculata andrographis_paniculata_XP_051133008.1
andrographis_paniculata_XP_051133009.1 andrographis_paniculata andrographis_paniculata_XP_051133009.1
andrographis_paniculata_XP_051133566.1 andrographis_paniculata andrographis_paniculata_XP_051133566.1
andrographis_paniculata_XP_051134082.1 andrographis_paniculata andrographis_paniculata_XP_051134082.1
andrographis_paniculata_XP_051134415.1 andrographis_paniculata andrographis_paniculata_XP_051134415.1
andrographis_paniculata_XP_051134424.1 andrographis_paniculata andrographis_paniculata_XP_051134424.1
andrographis_paniculata_XP_051134433.1 andrographis_paniculata andrographis_paniculata_XP_051134433.1
andrographis_paniculata_XP_051137793.1 andrographis_paniculata andrographis_paniculata_XP_051137793.1
andrographis_paniculata_XP_051137794.1 andrographis_paniculata andrographis_paniculata_XP_051137794.1
andrographis_paniculata_XP_051137795.1 andrographis_paniculata andrographis_paniculata_XP_051137795.1
andrographis_paniculata_XP_051137962.1 andrographis_paniculata andrographis_paniculata_XP_051137962.1
andrographis_paniculata_XP_051138462.1 andrographis_paniculata andrographis_paniculata_XP_051138462.1
andrographis_paniculata_XP_051142311.1 andrographis_paniculata andrographis_paniculata_XP_051142311.1
andrographis_paniculata_XP_051142364.1 andrographis_paniculata andrographis_paniculata_XP_051142364.1
andrographis_paniculata_XP_051142365.1 andrographis_paniculata andrographis_paniculata_XP_051142365.1
andrographis_paniculata_XP_051142366.1 andrographis_paniculata andrographis_paniculata_XP_051142366.1
andrographis_paniculata_XP_051142367.1 andrographis_paniculata andrographis_paniculata_XP_051142367.1
andrographis_paniculata_XP_051142626.1 andrographis_paniculata andrographis_paniculata_XP_051142626.1
andrographis_paniculata_XP_051142659.1 andrographis_paniculata andrographis_paniculata_XP_051142659.1
andrographis_paniculata_XP_051143084.1 andrographis_paniculata andrographis_paniculata_XP_051143084.1
andrographis_paniculata_XP_051143483.1 andrographis_paniculata andrographis_paniculata_XP_051143483.1
andrographis_paniculata_XP_051143496.1 andrographis_paniculata andrographis_paniculata_XP_051143496.1
andrographis_paniculata_XP_051143550.1 andrographis_paniculata andrographis_paniculata_XP_051143550.1
andrographis_paniculata_XP_051143551.1 andrographis_paniculata andrographis_paniculata_XP_051143551.1
andrographis_paniculata_XP_051143633.1 andrographis_paniculata andrographis_paniculata_XP_051143633.1
andrographis_paniculata_XP_051143709.1 andrographis_paniculata andrographis_paniculata_XP_051143709.1
andrographis_paniculata_XP_051146350.1 andrographis_paniculata andrographis_paniculata_XP_051146350.1