PlantSME Plant secondary metabolism enzyme database
SQE

SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage
Detected in 773 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Fragaria ananassa
Fragaria chiloensis
Rosa multiflora
Gossypium raimondii
Related Modules
Steroid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024
Sterol precursor formation
SQS/FDFT1 4389 SQE 4569 CAS 35857
Phytosterol backbone
SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689
Brassinosteroid branch
DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68
Family Gene List
GeneSpeciesProtein ID
nicotiana_tabacum_Nitab4.5_0001074g0020.1 nicotiana_tabacum nicotiana_tabacum_Nitab4.5_0001074g0020.1
nicotiana_tabacum_Nitab4.5_0001477g0160.1 nicotiana_tabacum nicotiana_tabacum_Nitab4.5_0001477g0160.1
nicotiana_tabacum_Nitab4.5_0001494g0100.1 nicotiana_tabacum nicotiana_tabacum_Nitab4.5_0001494g0100.1
nicotiana_tabacum_Nitab4.5_0002254g0020.1 nicotiana_tabacum nicotiana_tabacum_Nitab4.5_0002254g0020.1
nicotiana_tabacum_Nitab4.5_0003390g0020.1 nicotiana_tabacum nicotiana_tabacum_Nitab4.5_0003390g0020.1
nicotiana_tomentosiformis_XP_009609551.1 nicotiana_tomentosiformis nicotiana_tomentosiformis_XP_009609551.1
nicotiana_tomentosiformis_XP_009621693.1 nicotiana_tomentosiformis nicotiana_tomentosiformis_XP_009621693.1
nicotiana_tomentosiformis_XP_009624091.1 nicotiana_tomentosiformis nicotiana_tomentosiformis_XP_009624091.1
nicotiana_tomentosiformis_XP_018633037.1 nicotiana_tomentosiformis nicotiana_tomentosiformis_XP_018633037.1
nicotiana_tomentosiformis_XP_033509995.1 nicotiana_tomentosiformis nicotiana_tomentosiformis_XP_033509995.1
nicotiana_tomentosiformis_XP_033513886.1 nicotiana_tomentosiformis nicotiana_tomentosiformis_XP_033513886.1
nicotiana_tomentosiformis_XP_033513887.1 nicotiana_tomentosiformis nicotiana_tomentosiformis_XP_033513887.1
Nschscaffold12227_cov1130025950 nissolia_schottii Nschscaffold12227_cov1130025950
Nschscaffold3257_cov1080167730 nissolia_schottii Nschscaffold3257_cov1080167730
Nschscaffold524452_cov1140255850 nissolia_schottii Nschscaffold524452_cov1140255850
Nschscaffold524540_cov1170263290 nissolia_schottii Nschscaffold524540_cov1170263290
Nschscaffold524853_cov1170276320 nissolia_schottii Nschscaffold524853_cov1170276320
Ncon10611220027340 noteroclada_confluens Ncon10611220027340
Ncon13279750094930 noteroclada_confluens Ncon13279750094930
NcolGWHAAYW000000040081480.1 nymphaea_colorata NcolGWHAAYW000000040081480.1
NcolGWHAAYW000000120198160.1 nymphaea_colorata NcolGWHAAYW000000120198160.1
nyssa_yunnanensis_augustus-126-processed-gene-3.2-mRNA-1 nyssa_yunnanensis nyssa_yunnanensis_augustus-126-processed-gene-3.2-mRNA-1
nyssa_yunnanensis_augustus-199-processed-gene-4.3-mRNA-1 nyssa_yunnanensis nyssa_yunnanensis_augustus-199-processed-gene-4.3-mRNA-1
nyssa_yunnanensis_augustus-208277-processed-gene-0.0-mRNA-1 nyssa_yunnanensis nyssa_yunnanensis_augustus-208277-processed-gene-0.0-mRNA-1
nyssa_yunnanensis_augustus-265194-processed-gene-0.0-mRNA-1 nyssa_yunnanensis nyssa_yunnanensis_augustus-265194-processed-gene-0.0-mRNA-1
nyssa_yunnanensis_augustus-273679-processed-gene-0.1-mRNA-1 nyssa_yunnanensis nyssa_yunnanensis_augustus-273679-processed-gene-0.1-mRNA-1
nyssa_yunnanensis_augustus-420-processed-gene-8.0-mRNA-1 nyssa_yunnanensis nyssa_yunnanensis_augustus-420-processed-gene-8.0-mRNA-1
nyssa_yunnanensis_augustus-420-processed-gene-8.1-mRNA-1 nyssa_yunnanensis nyssa_yunnanensis_augustus-420-processed-gene-8.1-mRNA-1
nyssa_yunnanensis_augustus-579507-processed-gene-0.0-mRNA-1 nyssa_yunnanensis nyssa_yunnanensis_augustus-579507-processed-gene-0.0-mRNA-1
nyssa_yunnanensis_genemark-244679-processed-gene-0.1-mRNA-1 nyssa_yunnanensis nyssa_yunnanensis_genemark-244679-processed-gene-0.1-mRNA-1