PlantSME Plant secondary metabolism enzyme database
SQE

SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage
Detected in 773 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Fragaria ananassa
Fragaria chiloensis
Rosa multiflora
Gossypium raimondii
Related Modules
Steroid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024
Sterol precursor formation
SQS/FDFT1 4389 SQE 4569 CAS 35857
Phytosterol backbone
SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689
Brassinosteroid branch
DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68
Family Gene List
GeneSpeciesProtein ID
prunus_fruticosa_Athal_rna-NM_001343845.1_R3 prunus_fruticosa prunus_fruticosa_Athal_rna-NM_001343845.1_R3
prunus_fruticosa_Fves_FvH4_1g20540.1_R0 prunus_fruticosa prunus_fruticosa_Fves_FvH4_1g20540.1_R0
prunus_fruticosa_Fves_FvH4_4g14050.1_R0 prunus_fruticosa prunus_fruticosa_Fves_FvH4_4g14050.1_R0
prunus_fruticosa_Mdom_HF13173-RA_R1 prunus_fruticosa prunus_fruticosa_Mdom_HF13173-RA_R1
prunus_fruticosa_Mdom_HF27142-RA_R4 prunus_fruticosa prunus_fruticosa_Mdom_HF27142-RA_R4
prunus_fruticosa_Mdom_HF31514-RA_R0 prunus_fruticosa prunus_fruticosa_Mdom_HF31514-RA_R0
prunus_fruticosa_Mdom_HF35939-RA_R0 prunus_fruticosa prunus_fruticosa_Mdom_HF35939-RA_R0
prunus_fruticosa_Mdom_HF35941-RA_R0 prunus_fruticosa prunus_fruticosa_Mdom_HF35941-RA_R0
prunus_fruticosa_Parm_rna-CURHAP_LOCUS39472_R0 prunus_fruticosa prunus_fruticosa_Parm_rna-CURHAP_LOCUS39472_R0
prunus_fruticosa_Parm_rna-CURHAP_LOCUS50947_R0 prunus_fruticosa prunus_fruticosa_Parm_rna-CURHAP_LOCUS50947_R0
prunus_fruticosa_Pavi_rna-XM_021945744.1_R0 prunus_fruticosa prunus_fruticosa_Pavi_rna-XM_021945744.1_R0
prunus_fruticosa_Pavi_rna-XM_021947499.1_R0 prunus_fruticosa prunus_fruticosa_Pavi_rna-XM_021947499.1_R0
prunus_fruticosa_Pavi_rna-XM_021958785.1_R0 prunus_fruticosa prunus_fruticosa_Pavi_rna-XM_021958785.1_R0
prunus_fruticosa_Pavi_rna-XM_021972313.1_R3 prunus_fruticosa prunus_fruticosa_Pavi_rna-XM_021972313.1_R3
prunus_fruticosa_Pper_rna-XM_020553567.1_R0 prunus_fruticosa prunus_fruticosa_Pper_rna-XM_020553567.1_R0
prunus_humilis_GWHPBCKI001966 prunus_humilis prunus_humilis_GWHPBCKI001966
prunus_humilis_GWHPBCKI008942 prunus_humilis prunus_humilis_GWHPBCKI008942
prunus_humilis_GWHPBCKI008943 prunus_humilis prunus_humilis_GWHPBCKI008943
prunus_humilis_GWHPBCKI026202 prunus_humilis prunus_humilis_GWHPBCKI026202
prunus_humilis_GWHPBCKI026203 prunus_humilis prunus_humilis_GWHPBCKI026203
prunus_humilis_GWHPBCKI026204 prunus_humilis prunus_humilis_GWHPBCKI026204
prunus_humilis_GWHPBCKI026205 prunus_humilis prunus_humilis_GWHPBCKI026205
prunus_kansuensis_Pka01g4274 prunus_kansuensis prunus_kansuensis_Pka01g4274
prunus_kansuensis_Pka06g2257 prunus_kansuensis prunus_kansuensis_Pka06g2257
prunus_kansuensis_Pka08g1618 prunus_kansuensis prunus_kansuensis_Pka08g1618
prunus_kansuensis_Pka08g1619 prunus_kansuensis prunus_kansuensis_Pka08g1619
prunus_kansuensis_Pka08g1620 prunus_kansuensis prunus_kansuensis_Pka08g1620
prunus_kanzakura_KWZCAM1g3844.1 prunus_kanzakura prunus_kanzakura_KWZCAM1g3844.1
prunus_kanzakura_KWZCAM6g1547.1 prunus_kanzakura prunus_kanzakura_KWZCAM6g1547.1
prunus_kanzakura_KWZCAM6g4377.1 prunus_kanzakura prunus_kanzakura_KWZCAM6g4377.1