PlantSME Plant secondary metabolism enzyme database
SQE

SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage
Detected in 773 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Fragaria ananassa
Fragaria chiloensis
Rosa multiflora
Gossypium raimondii
Related Modules
Steroid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024
Sterol precursor formation
SQS/FDFT1 4389 SQE 4569 CAS 35857
Phytosterol backbone
SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689
Brassinosteroid branch
DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68
Family Gene List
GeneSpeciesProtein ID
Smil03G0022120.1 salvia_miltiorrhiza Smil03G0022120.1
salvia_rosmarinus_1042.g481.t1 salvia_rosmarinus salvia_rosmarinus_1042.g481.t1
salvia_rosmarinus_1044.g12.t1 salvia_rosmarinus salvia_rosmarinus_1044.g12.t1
salvia_rosmarinus_1153.g477.t1 salvia_rosmarinus salvia_rosmarinus_1153.g477.t1
salvia_rosmarinus_1153.g692.t1 salvia_rosmarinus salvia_rosmarinus_1153.g692.t1
salvia_rosmarinus_1153.g692.t1.1.5db2117b salvia_rosmarinus salvia_rosmarinus_1153.g692.t1.1.5db2117b
salvia_rosmarinus_2419.g186.t1 salvia_rosmarinus salvia_rosmarinus_2419.g186.t1
salvia_rosmarinus_294153.g2.t1 salvia_rosmarinus salvia_rosmarinus_294153.g2.t1
salvia_rosmarinus_344831.g1.t1 salvia_rosmarinus salvia_rosmarinus_344831.g1.t1
salvia_rosmarinus_349500.g6.t1 salvia_rosmarinus salvia_rosmarinus_349500.g6.t1
ScucSacu_v1.1_s00140038370 salvinia_cucullata ScucSacu_v1.1_s00140038370
Suncscaffold_150124790 sanionia_uncinata Suncscaffold_150124790
Suncscaffold_90286930 sanionia_uncinata Suncscaffold_90286930
santalum_album_GWHPCBHT006071 santalum_album santalum_album_GWHPCBHT006071
santalum_album_GWHPCBHT011619 santalum_album santalum_album_GWHPCBHT011619
santalum_yasi_GWHPCBIR004142 santalum_yasi santalum_yasi_GWHPCBIR004142
santalum_yasi_GWHPCBIR007000 santalum_yasi santalum_yasi_GWHPCBIR007000
sapria_himalayana_SHI08449-RA sapria_himalayana sapria_himalayana_SHI08449-RA
sapria_himalayana_SHI08452-RA sapria_himalayana sapria_himalayana_SHI08452-RA
sapria_himalayana_SHI15530-RA sapria_himalayana sapria_himalayana_SHI15530-RA
SAchi01G0006300.1 saururus_chinensis SAchi01G0006300.1
SAchi01G0006310.1 saururus_chinensis SAchi01G0006310.1
SAchi01G0018080.1 saururus_chinensis SAchi01G0018080.1
SAchi03G0005810.1 saururus_chinensis SAchi03G0005810.1
SAchi10G0020040.1 saururus_chinensis SAchi10G0020040.1
scalesia_atractyloides_augustus_masked-chr_5-processed-gene-1037.5-mRNA-1 scalesia_atractyloides scalesia_atractyloides_augustus_masked-chr_5-processed-gene-1037.5-mRNA-1
scalesia_atractyloides_maker-chr_10-augustus-gene-287.21-mRNA-1 scalesia_atractyloides scalesia_atractyloides_maker-chr_10-augustus-gene-287.21-mRNA-1
scalesia_atractyloides_maker-chr_11-augustus-gene-20.30-mRNA-1 scalesia_atractyloides scalesia_atractyloides_maker-chr_11-augustus-gene-20.30-mRNA-1
scalesia_atractyloides_maker-chr_13-augustus-gene-886.1-mRNA-1 scalesia_atractyloides scalesia_atractyloides_maker-chr_13-augustus-gene-886.1-mRNA-1
scalesia_atractyloides_maker-chr_14-augustus-gene-5.17-mRNA-1 scalesia_atractyloides scalesia_atractyloides_maker-chr_14-augustus-gene-5.17-mRNA-1