PlantSME Plant secondary metabolism enzyme database
SQE

SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage
Detected in 773 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Fragaria ananassa
Fragaria chiloensis
Rosa multiflora
Gossypium raimondii
Related Modules
Steroid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024
Sterol precursor formation
SQS/FDFT1 4389 SQE 4569 CAS 35857
Phytosterol backbone
SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689
Brassinosteroid branch
DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68
Family Gene List
GeneSpeciesProtein ID
solanum_aethiopicum_Soaet10025696 solanum_aethiopicum solanum_aethiopicum_Soaet10025696
solanum_aethiopicum_Soaet10031752 solanum_aethiopicum solanum_aethiopicum_Soaet10031752
solanum_aethiopicum_Soaet10035103 solanum_aethiopicum solanum_aethiopicum_Soaet10035103
solanum_galapagense_GWHPBJTJ007837 solanum_galapagense solanum_galapagense_GWHPBJTJ007837
solanum_galapagense_GWHPBJTJ012104 solanum_galapagense solanum_galapagense_GWHPBJTJ012104
solanum_galapagense_GWHPBJTJ020220 solanum_galapagense solanum_galapagense_GWHPBJTJ020220
solanum_galapagense_GWHPBJTJ024444 solanum_galapagense solanum_galapagense_GWHPBJTJ024444
solanum_habrochaites_GWHPBJTH012132 solanum_habrochaites solanum_habrochaites_GWHPBJTH012132
solanum_habrochaites_GWHPBJTH024573 solanum_habrochaites solanum_habrochaites_GWHPBJTH024573
solanum_lycopersicoides_Contig297g050140.1 solanum_lycopersicoides solanum_lycopersicoides_Contig297g050140.1
solanum_lycopersicoides_Solyd01g087190.1 solanum_lycopersicoides solanum_lycopersicoides_Solyd01g087190.1
solanum_lycopersicoides_Solyd02g057160.1 solanum_lycopersicoides solanum_lycopersicoides_Solyd02g057160.1
solanum_lycopersicoides_Solyd02g057210.1 solanum_lycopersicoides solanum_lycopersicoides_Solyd02g057210.1
solanum_lycopersicoides_Solyd04g074310.1 solanum_lycopersicoides solanum_lycopersicoides_Solyd04g074310.1
solanum_lycopersicoides_Solyd04g074360.1 solanum_lycopersicoides solanum_lycopersicoides_Solyd04g074360.1
solanum_lycopersicoides_Solyd11g062280.1 solanum_lycopersicoides solanum_lycopersicoides_Solyd11g062280.1
Slyc00G0005090.1 solanum_lycopersicum Slyc00G0005090.1
Slyc02G0008640.1 solanum_lycopersicum Slyc02G0008640.1
Slyc02G0008660.1 solanum_lycopersicum Slyc02G0008660.1
Slyc04G0011510.1 solanum_lycopersicum Slyc04G0011510.1
Slyc04G0012290.1 solanum_lycopersicum Slyc04G0012290.1
Slyc04G0022550.1 solanum_lycopersicum Slyc04G0022550.1
Slyc06G0013640.1 solanum_lycopersicum Slyc06G0013640.1
Slyc11G0015720.1 solanum_lycopersicum Slyc11G0015720.1
Smel02G0023640.1 solanum_melongena Smel02G0023640.1
Smel04G0018380.1 solanum_melongena Smel04G0018380.1
Smel05G0023720.1 solanum_melongena Smel05G0023720.1
SOpen02G0013620.1 solanum_pennellii SOpen02G0013620.1
SOpen02G0013650.1 solanum_pennellii SOpen02G0013650.1
SOpen04G0030030.1 solanum_pennellii SOpen04G0030030.1