SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage

Detected in 773 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
artemisia_argyi_GWHPBRAE056040	artemisia_argyi	artemisia_argyi_GWHPBRAE056040
artemisia_argyi_GWHPBRAE057510	artemisia_argyi	artemisia_argyi_GWHPBRAE057510
artemisia_argyi_GWHPBRAE057534	artemisia_argyi	artemisia_argyi_GWHPBRAE057534
artemisia_argyi_GWHPBRAE061027	artemisia_argyi	artemisia_argyi_GWHPBRAE061027
artemisia_tridentata_ANN12915-RA	artemisia_tridentata	artemisia_tridentata_ANN12915-RA
artemisia_tridentata_ANN13000-RA	artemisia_tridentata	artemisia_tridentata_ANN13000-RA
artemisia_tridentata_ANN22749-RA	artemisia_tridentata	artemisia_tridentata_ANN22749-RA
artemisia_tridentata_ANN32748-RA	artemisia_tridentata	artemisia_tridentata_ANN32748-RA
Aaltiscaffold1200039540.1	artocarpus_altilis	Aaltiscaffold1200039540.1
Aaltiscaffold18580111770.1	artocarpus_altilis	Aaltiscaffold18580111770.1
Aaltiscaffold20138530.1	artocarpus_altilis	Aaltiscaffold20138530.1
Aaltiscaffold2090151150.1	artocarpus_altilis	Aaltiscaffold2090151150.1
Aaltiscaffold23720168990.1	artocarpus_altilis	Aaltiscaffold23720168990.1
Aaltiscaffold5090254720.1	artocarpus_altilis	Aaltiscaffold5090254720.1
Ahetscaffold1772410055990.1	artocarpus_heterophyllus	Ahetscaffold1772410055990.1
Ahetscaffold1805980162210.1	artocarpus_heterophyllus	Ahetscaffold1805980162210.1
Ahetscaffold1806780170340.1	artocarpus_heterophyllus	Ahetscaffold1806780170340.1
Ahetscaffold1808790186380.1	artocarpus_heterophyllus	Ahetscaffold1808790186380.1
Ahetscaffold39740271960.1	artocarpus_heterophyllus	Ahetscaffold39740271960.1
Ahetscaffold40273520.1	artocarpus_heterophyllus	Ahetscaffold40273520.1
Ahetscaffold4550281550.1	artocarpus_heterophyllus	Ahetscaffold4550281550.1
artocarpus_nanchuanensis_EVM0002157.1	artocarpus_nanchuanensis	artocarpus_nanchuanensis_EVM0002157.1
artocarpus_nanchuanensis_EVM0003023.1	artocarpus_nanchuanensis	artocarpus_nanchuanensis_EVM0003023.1
artocarpus_nanchuanensis_EVM0008025.1	artocarpus_nanchuanensis	artocarpus_nanchuanensis_EVM0008025.1
artocarpus_nanchuanensis_EVM0013698.1	artocarpus_nanchuanensis	artocarpus_nanchuanensis_EVM0013698.1
artocarpus_nanchuanensis_EVM0021837.1	artocarpus_nanchuanensis	artocarpus_nanchuanensis_EVM0021837.1
artocarpus_nanchuanensis_EVM0034510.1	artocarpus_nanchuanensis	artocarpus_nanchuanensis_EVM0034510.1
artocarpus_nanchuanensis_EVM0038430.1	artocarpus_nanchuanensis	artocarpus_nanchuanensis_EVM0038430.1
asparagus_kiusianus_K1p1ch01g29910	asparagus_kiusianus	asparagus_kiusianus_K1p1ch01g29910
asparagus_kiusianus_K1p1ch03g01282	asparagus_kiusianus	asparagus_kiusianus_K1p1ch03g01282