SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage

Detected in 773 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
typha_angustifolia_xp07326	typha_angustifolia	typha_angustifolia_xp07326
typha_angustifolia_xp08831	typha_angustifolia	typha_angustifolia_xp08831
typha_latifolia_tl.00g160350.m01.polypeptide	typha_latifolia	typha_latifolia_tl.00g160350.m01.polypeptide
Uhut1132810036150	ulota_hutchinsiae	Uhut1132810036150
Uhut230114320	ulota_hutchinsiae	Uhut230114320
Uhut690192490	ulota_hutchinsiae	Uhut690192490
jgi\|Ulvmu1\|7543\|UM037_0087.1	ulva_mutabilis	jgi\|Ulvmu1\|7543\|UM037_0087.1
Ugibunitig_320099540	utricularia_gibba	Ugibunitig_320099540
Ugibunitig_620168830	utricularia_gibba	Ugibunitig_620168830
Ugibunitig_7470210950	utricularia_gibba	Ugibunitig_7470210950
Urenscaffold145_size5684890058160.1	utricularia_reniformis	Urenscaffold145_size5684890058160.1
Urenscaffold147_size5610640059630.1	utricularia_reniformis	Urenscaffold147_size5610640059630.1
Urenscaffold349_size3058350213920.1	utricularia_reniformis	Urenscaffold349_size3058350213920.1
Urenscaffold74_size8182170375350.1	utricularia_reniformis	Urenscaffold74_size8182170375350.1
vaccinium_bracteatum_GWHPBPBP008544	vaccinium_bracteatum	vaccinium_bracteatum_GWHPBPBP008544
vaccinium_bracteatum_GWHPBPBP016505	vaccinium_bracteatum	vaccinium_bracteatum_GWHPBPBP016505
vaccinium_bracteatum_GWHPBPBP025120	vaccinium_bracteatum	vaccinium_bracteatum_GWHPBPBP025120
vaccinium_bracteatum_GWHPBPBP026839	vaccinium_bracteatum	vaccinium_bracteatum_GWHPBPBP026839
vaccinium_bracteatum_GWHPBPBP035581	vaccinium_bracteatum	vaccinium_bracteatum_GWHPBPBP035581
vaccinium_darrowii_Vadar_g1983.t1	vaccinium_darrowii	vaccinium_darrowii_Vadar_g1983.t1
vaccinium_darrowii_Vadar_g20480.t1	vaccinium_darrowii	vaccinium_darrowii_Vadar_g20480.t1
vaccinium_darrowii_Vadar_g23954.t1	vaccinium_darrowii	vaccinium_darrowii_Vadar_g23954.t1
vaccinium_darrowii_Vadar_g26883.t1	vaccinium_darrowii	vaccinium_darrowii_Vadar_g26883.t1
vaccinium_myrtillus_Vmy04g28321.t1	vaccinium_myrtillus	vaccinium_myrtillus_Vmy04g28321.t1
vaccinium_myrtillus_Vmy05g11965.t1	vaccinium_myrtillus	vaccinium_myrtillus_Vmy05g11965.t1
vaccinium_myrtillus_Vmy07g25722.t1	vaccinium_myrtillus	vaccinium_myrtillus_Vmy07g25722.t1
vaccinium_myrtillus_Vmy08g19542.t1	vaccinium_myrtillus	vaccinium_myrtillus_Vmy08g19542.t1
vaccinium_myrtillus_Vmy09g22566.t1	vaccinium_myrtillus	vaccinium_myrtillus_Vmy09g22566.t1
KAG0460621.1[Vanilla	vanilla_planifolia	KAG0460621.1[Vanilla
KAG0463502.1[Vanilla	vanilla_planifolia	KAG0463502.1[Vanilla