SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage

Detected in 773 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
Cmel01G0001500.1	cucumis_melo	Cmel01G0001500.1
Cmel03G0021070.1	cucumis_melo	Cmel03G0021070.1
Cmel07G0002560.1	cucumis_melo	Cmel07G0002560.1
CUsat02G0019290.1	cucumis_sativus	CUsat02G0019290.1
CUsat04G0025750.1	cucumis_sativus	CUsat04G0025750.1
CUsat07G0006790.1	cucumis_sativus	CUsat07G0006790.1
CargCucurbita_argyrosperma_scaffold_0310082380.1	cucurbita_argyrosperma	CargCucurbita_argyrosperma_scaffold_0310082380.1
CargCucurbita_argyrosperma_scaffold_0360093260.1	cucurbita_argyrosperma	CargCucurbita_argyrosperma_scaffold_0360093260.1
CargCucurbita_argyrosperma_scaffold_0880164830.1	cucurbita_argyrosperma	CargCucurbita_argyrosperma_scaffold_0880164830.1
CargCucurbita_argyrosperma_scaffold_0880165480.1	cucurbita_argyrosperma	CargCucurbita_argyrosperma_scaffold_0880165480.1
CargCucurbita_argyrosperma_scaffold_1980235140.1	cucurbita_argyrosperma	CargCucurbita_argyrosperma_scaffold_1980235140.1
Cmax01G0017610.1	cucurbita_maxima	Cmax01G0017610.1
Cmax05G0001210.1	cucurbita_maxima	Cmax05G0001210.1
Cmax09G0003160.1	cucurbita_maxima	Cmax09G0003160.1
Cmax09G0003170.1	cucurbita_maxima	Cmax09G0003170.1
Cmax12G0006160.1	cucurbita_maxima	Cmax12G0006160.1
Cmax19G0005160.1	cucurbita_maxima	Cmax19G0005160.1
Cmos01G0018190.1	cucurbita_moschata	Cmos01G0018190.1
Cmos05G0001230.1	cucurbita_moschata	Cmos05G0001230.1
Cmos09G0003150.1	cucurbita_moschata	Cmos09G0003150.1
Cmos12G0005520.1	cucurbita_moschata	Cmos12G0005520.1
Cmos12G0005530.1	cucurbita_moschata	Cmos12G0005530.1
Cmos19G0005290.1	cucurbita_moschata	Cmos19G0005290.1
Cpep02G0002410.1	cucurbita_pepo	Cpep02G0002410.1
Cpep06G0002230.1	cucurbita_pepo	Cpep06G0002230.1
Cpep07G0005340.1	cucurbita_pepo	Cpep07G0005340.1
Cpep11G0001050.1	cucurbita_pepo	Cpep11G0001050.1
Cpep15G0004120.1	cucurbita_pepo	Cpep15G0004120.1
CausC039N0138510	cuscuta_australis	CausC039N0138510
CcamCcam0.32_scaffold135b0062610.1	cuscuta_campestris	CcamCcam0.32_scaffold135b0062610.1