PlantSME Plant secondary metabolism enzyme database
SQE

SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage
Detected in 773 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Fragaria ananassa
Fragaria chiloensis
Rosa multiflora
Gossypium raimondii
Related Modules
Steroid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024
Sterol precursor formation
SQS/FDFT1 4389 SQE 4569 CAS 35857
Phytosterol backbone
SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689
Brassinosteroid branch
DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68
Family Gene List
GeneSpeciesProtein ID
Fjavscaffold_130070170 fissidens_javanicus Fjavscaffold_130070170
Fjavscaffold_70229810 fissidens_javanicus Fjavscaffold_70229810
Fontinalis2696350033570 fontinalis Fontinalis2696350033570
Fontinalis2765010069790 fontinalis Fontinalis2765010069790
Fant1762720068790.1 fontinalis_antipyretica Fant1762720068790.1
Fsul2696350033570 fontinalis_sullivantii Fsul2696350033570
Fsul2765010069790 fontinalis_sullivantii Fsul2765010069790
fortunella_hindsii_sjg022620.1 fortunella_hindsii fortunella_hindsii_sjg022620.1
fortunella_hindsii_sjg143440.1 fortunella_hindsii fortunella_hindsii_sjg143440.1
fortunella_hindsii_sjg144720.1 fortunella_hindsii fortunella_hindsii_sjg144720.1
fortunella_hindsii_sjg148020.1 fortunella_hindsii fortunella_hindsii_sjg148020.1
fortunella_hindsii_sjg183880.1 fortunella_hindsii fortunella_hindsii_sjg183880.1
fortunella_hindsii_sjg216470.1 fortunella_hindsii fortunella_hindsii_sjg216470.1
fortunella_hindsii_sjg284730.1 fortunella_hindsii fortunella_hindsii_sjg284730.1
fortunella_hindsii_sjg315230.1 fortunella_hindsii fortunella_hindsii_sjg315230.1
Fossombronia10530015380 fossombronia Fossombronia10530015380
Fossombronia1950122910 fossombronia Fossombronia1950122910
Fossombronia2370149020 fossombronia Fossombronia2370149020
Fossombronia6220245970 fossombronia Fossombronia6220245970
Fossombronia6220246040 fossombronia Fossombronia6220246040
FanaFAN_r2.3ch00006980 fragaria_ananassa FanaFAN_r2.3ch00006980
FanaFAN_r2.3ch00016460 fragaria_ananassa FanaFAN_r2.3ch00016460
FanaFAN_r2.3ch00016470 fragaria_ananassa FanaFAN_r2.3ch00016470
FanaFAN_r2.3ch00023000 fragaria_ananassa FanaFAN_r2.3ch00023000
FanaFAN_r2.3ch00026850 fragaria_ananassa FanaFAN_r2.3ch00026850
FanaFAN_r2.3ch00028190 fragaria_ananassa FanaFAN_r2.3ch00028190
FanaFAN_r2.3ch00048670 fragaria_ananassa FanaFAN_r2.3ch00048670
FanaFAN_r2.3ch00051960 fragaria_ananassa FanaFAN_r2.3ch00051960
FanaFAN_r2.3ch00058490 fragaria_ananassa FanaFAN_r2.3ch00058490
FanaFAN_r2.3ch00070160 fragaria_ananassa FanaFAN_r2.3ch00070160