PlantSME Plant secondary metabolism enzyme database
SQE

SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage
Detected in 773 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Fragaria ananassa
Fragaria chiloensis
Rosa multiflora
Gossypium raimondii
Related Modules
Steroid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024
Sterol precursor formation
SQS/FDFT1 4389 SQE 4569 CAS 35857
Phytosterol backbone
SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689
Brassinosteroid branch
DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68
Family Gene List
GeneSpeciesProtein ID
Fves04G0019860.1 fragaria_vesca Fves04G0019860.1
Fves04G0019890.1 fragaria_vesca Fves04G0019890.1
Fves04G0019900.1 fragaria_vesca Fves04G0019900.1
Fves05G0016660.1 fragaria_vesca Fves05G0016660.1
Fves05G0016770.1 fragaria_vesca Fves05G0016770.1
fragaria_x_ananassa_augustus_masked-Fvb1-3-processed-gene-107.5-mRNA-1 fragaria_x_ananassa fragaria_x_ananassa_augustus_masked-Fvb1-3-processed-gene-107.5-mRNA-1
fragaria_x_ananassa_augustus_masked-Fvb2-1-processed-gene-214.6-mRNA-1 fragaria_x_ananassa fragaria_x_ananassa_augustus_masked-Fvb2-1-processed-gene-214.6-mRNA-1
fragaria_x_ananassa_augustus_masked-Fvb2-2-processed-gene-219.5-mRNA-1 fragaria_x_ananassa fragaria_x_ananassa_augustus_masked-Fvb2-2-processed-gene-219.5-mRNA-1
fragaria_x_ananassa_augustus_masked-Fvb3-1-processed-gene-121.2-mRNA-1 fragaria_x_ananassa fragaria_x_ananassa_augustus_masked-Fvb3-1-processed-gene-121.2-mRNA-1
fragaria_x_ananassa_augustus_masked-Fvb3-4-processed-gene-7.14-mRNA-1 fragaria_x_ananassa fragaria_x_ananassa_augustus_masked-Fvb3-4-processed-gene-7.14-mRNA-1
fragaria_x_ananassa_maker-Fvb1-1-augustus-gene-152.24-mRNA-1 fragaria_x_ananassa fragaria_x_ananassa_maker-Fvb1-1-augustus-gene-152.24-mRNA-1
fragaria_x_ananassa_maker-Fvb1-1-snap-gene-173.46-mRNA-1 fragaria_x_ananassa fragaria_x_ananassa_maker-Fvb1-1-snap-gene-173.46-mRNA-1
fragaria_x_ananassa_maker-Fvb1-1-snap-gene-173.48-mRNA-1 fragaria_x_ananassa fragaria_x_ananassa_maker-Fvb1-1-snap-gene-173.48-mRNA-1
fragaria_x_ananassa_maker-Fvb1-2-augustus-gene-286.11-mRNA-1 fragaria_x_ananassa fragaria_x_ananassa_maker-Fvb1-2-augustus-gene-286.11-mRNA-1
fragaria_x_ananassa_maker-Fvb1-2-snap-gene-118.47-mRNA-1 fragaria_x_ananassa fragaria_x_ananassa_maker-Fvb1-2-snap-gene-118.47-mRNA-1
fragaria_x_ananassa_maker-Fvb1-2-snap-gene-118.48-mRNA-1 fragaria_x_ananassa fragaria_x_ananassa_maker-Fvb1-2-snap-gene-118.48-mRNA-1
fragaria_x_ananassa_maker-Fvb1-3-augustus-gene-129.21-mRNA-1 fragaria_x_ananassa fragaria_x_ananassa_maker-Fvb1-3-augustus-gene-129.21-mRNA-1
fragaria_x_ananassa_maker-Fvb1-4-augustus-gene-226.19-mRNA-1 fragaria_x_ananassa fragaria_x_ananassa_maker-Fvb1-4-augustus-gene-226.19-mRNA-1
fragaria_x_ananassa_maker-Fvb1-4-augustus-gene-95.46-mRNA-1 fragaria_x_ananassa fragaria_x_ananassa_maker-Fvb1-4-augustus-gene-95.46-mRNA-1
fragaria_x_ananassa_maker-Fvb2-1-augustus-gene-8.45-mRNA-1 fragaria_x_ananassa fragaria_x_ananassa_maker-Fvb2-1-augustus-gene-8.45-mRNA-1
fragaria_x_ananassa_maker-Fvb2-1-augustus-gene-8.46-mRNA-1 fragaria_x_ananassa fragaria_x_ananassa_maker-Fvb2-1-augustus-gene-8.46-mRNA-1
fragaria_x_ananassa_maker-Fvb2-1-snap-gene-8.56-mRNA-1 fragaria_x_ananassa fragaria_x_ananassa_maker-Fvb2-1-snap-gene-8.56-mRNA-1
fragaria_x_ananassa_maker-Fvb2-1-snap-gene-9.31-mRNA-1 fragaria_x_ananassa fragaria_x_ananassa_maker-Fvb2-1-snap-gene-9.31-mRNA-1
fragaria_x_ananassa_maker-Fvb2-1-snap-gene-9.33-mRNA-1 fragaria_x_ananassa fragaria_x_ananassa_maker-Fvb2-1-snap-gene-9.33-mRNA-1
fragaria_x_ananassa_maker-Fvb2-2-augustus-gene-219.43-mRNA-1 fragaria_x_ananassa fragaria_x_ananassa_maker-Fvb2-2-augustus-gene-219.43-mRNA-1
fragaria_x_ananassa_maker-Fvb2-2-augustus-gene-219.52-mRNA-1 fragaria_x_ananassa fragaria_x_ananassa_maker-Fvb2-2-augustus-gene-219.52-mRNA-1
fragaria_x_ananassa_maker-Fvb2-2-snap-gene-219.71-mRNA-1 fragaria_x_ananassa fragaria_x_ananassa_maker-Fvb2-2-snap-gene-219.71-mRNA-1
fragaria_x_ananassa_maker-Fvb2-2-snap-gene-9.49-mRNA-1 fragaria_x_ananassa fragaria_x_ananassa_maker-Fvb2-2-snap-gene-9.49-mRNA-1
fragaria_x_ananassa_maker-Fvb2-3-augustus-gene-220.46-mRNA-1 fragaria_x_ananassa fragaria_x_ananassa_maker-Fvb2-3-augustus-gene-220.46-mRNA-1
fragaria_x_ananassa_maker-Fvb2-3-augustus-gene-221.21-mRNA-1 fragaria_x_ananassa fragaria_x_ananassa_maker-Fvb2-3-augustus-gene-221.21-mRNA-1