PlantSME Plant secondary metabolism enzyme database
SQE

SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage
Detected in 773 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Fragaria ananassa
Fragaria chiloensis
Rosa multiflora
Gossypium raimondii
Related Modules
Steroid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024
Sterol precursor formation
SQS/FDFT1 4389 SQE 4569 CAS 35857
Phytosterol backbone
SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689
Brassinosteroid branch
DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68
Family Gene List
GeneSpeciesProtein ID
HimpHimp2_scaffold_88770285080.1 handroanthus_impetiginosus HimpHimp2_scaffold_88770285080.1
HimpHimp2_scaffold_88770285090.1 handroanthus_impetiginosus HimpHimp2_scaffold_88770285090.1
Haplomitrium10252800012810 haplomitrium Haplomitrium10252800012810
Haplomitrium10659910042400 haplomitrium Haplomitrium10659910042400
Haplomitrium10823580068280 haplomitrium Haplomitrium10823580068280
Haplomitrium11045320162910 haplomitrium Haplomitrium11045320162910
Hcilscaffold_10032600 hedwigia_ciliata Hcilscaffold_10032600
Hcilscaffold_60144810 hedwigia_ciliata Hcilscaffold_60144810
Hann03G0000560.1 helianthus_annuus Hann03G0000560.1
Hann04G0016530.1 helianthus_annuus Hann04G0016530.1
Hann05G0008080.1 helianthus_annuus Hann05G0008080.1
Hann06G0019570.1 helianthus_annuus Hann06G0019570.1
Hann10G0018120.1 helianthus_annuus Hann10G0018120.1
Hann10G0038520.1 helianthus_annuus Hann10G0038520.1
Hann13G0000500.1 helianthus_annuus Hann13G0000500.1
Hann14G0018860.1 helianthus_annuus Hann14G0018860.1
Hann15G0027560.1 helianthus_annuus Hann15G0027560.1
heliophila_variabilis_HV01G015400 heliophila_variabilis heliophila_variabilis_HV01G015400
heliophila_variabilis_HV01G015410 heliophila_variabilis heliophila_variabilis_HV01G015410
heliophila_variabilis_HV01G015420 heliophila_variabilis heliophila_variabilis_HV01G015420
heliophila_variabilis_HV01G017150 heliophila_variabilis heliophila_variabilis_HV01G017150
heliophila_variabilis_HV05G025170 heliophila_variabilis heliophila_variabilis_HV05G025170
heliophila_variabilis_HV06G006840 heliophila_variabilis heliophila_variabilis_HV06G006840
heliophila_variabilis_HV07G025640 heliophila_variabilis heliophila_variabilis_HV07G025640
heliophila_variabilis_HV11G017220 heliophila_variabilis heliophila_variabilis_HV11G017220
heliophila_variabilis_HV11G027340 heliophila_variabilis heliophila_variabilis_HV11G027340
HhamSuperscaffold100066940 hibiscus_hamabo HhamSuperscaffold100066940
HhamSuperscaffold110088360 hibiscus_hamabo HhamSuperscaffold110088360
HhamSuperscaffold150177880 hibiscus_hamabo HhamSuperscaffold150177880
HhamSuperscaffold160211060 hibiscus_hamabo HhamSuperscaffold160211060