PlantSME Plant secondary metabolism enzyme database
Phenylpropanoid portable pathway

Phenylpropanoid portable pathway

Category：Phenylpropanoid pathway

Phenylpropanoid pathway definition imported from the 2026-05-17 portable BLAST/HMM package.

Representative Phenylpropanoid Reaction Route
Entry backbone to monolignol/lignin branches. Substrates, products, and condensed structural formulae show representative conversions; resolved reactions are shown as single enzymes, whereas multi-enzyme branches are shown as curated modules. Member counts come from public annotations.
6 curated steps/modules
Entry Backbone And Lignin Direction
01
Substrate
L-Phenylalanine
C9H11NO2
C6H5-CH2-CH(NH2)-COOH
Deamination to form the phenylpropene acid scaffold
PAL196
Product
trans-Cinnamic acid
C9H8O2
C6H5-CH=CH-COOH
PAL commits the amino-acid substrate to phenylpropanoid metabolism.
02
Substrate
trans-Cinnamic acid
C9H8O2
C6H5-CH=CH-COOH
Para-hydroxylation of the aromatic ring
C4H193
Product
p-Coumaric acid
C9H8O3
4-HO-C6H4-CH=CH-COOH
C4H/CYP73A introduces the 4-hydroxyl group for downstream CoA activation.
03
Substrate
p-Coumaric acid
C9H8O3
4-HO-C6H4-CH=CH-COOH
Substrate
CoA
C21H36N7O16P3S
CoA-SH
CoA ligation and activation
4CL771
Product
p-Coumaroyl-CoA
C30H38N7O18P3S
4-HO-C6H4-CH=CH-C(=O)-SCoA
4CL converts the free acid into a thioester used by condensation, acyltransfer, and reduction reactions.
04
Substrate
p-Coumaroyl-CoA
C30H38N7O18P3S
4-HO-C6H4-CH=CH-C(=O)-SCoA
Hydroxylation, acyl transfer, and methylation
HCT676 C3'H/CYP98A400 CSE681 CCoAOMT130
Product
Feruloyl-CoA-type intermediates
C31H40N7O19P3S
3-MeO-4-HO-C6H3-CH=CH-C(=O)-SCoA
This segment remodels the p-coumaroyl scaffold into caffeoyl/feruloyl-type intermediates.
05
Substrate
Hydroxycinnamoyl-CoA
C30-31 CoA thioesters
Ar-CH=CH-C(=O)-SCoA
Reduction and S/G monolignol formation
CCR505 CAD711 F5H/CYP84A83 COMT604
Product
Coniferyl/sinapyl alcohol
C10H12O3 / C11H14O4
Ar-CH=CH-CH2OH
CCR/CAD and related steps route CoA thioesters toward monolignol monomers.
06
Substrate
Monolignols
C9-C11 phenylpropanoids
Ar-CH=CH-CH2OH
Oxidative coupling and polymerization
LAC945 POD2554
Product
Lignin polymer
(C9 unit)n
[Ar-C3]n ether/C-C polymer
LAC/POD oxidatively couple monolignols into lignin polymers.
Lineage Distribution
Assignments under this module are distributed across the following plant lineages.
All Lineages Basal angiosperms (8449)
Current lineage filter: Basal angiosperms. All species, family, module, and gene statistics below have been narrowed to this lineage.
Algae
Hits0
Bryophytes
Hits0
Lycophytes/Ferns
Hits0
Gymnosperms
Hits0
Basal angiosperms
Hits8449
Monocots
Hits0
Eudicots
Hits0
Species Distribution
Brasenia schreberi
Annona cherimola
Cinnamomum kanehirae
Chloranthus sessilifolius
Amborella trichopoda
Aristolochia contorta
Cinnamomum camphora
Piper nigrum
Liriodendron chinense
Piper longum
Lineage Summary
Basal angiosperms
8449
Module Gene List
Reset
GeneSpeciesProtein ID
cinnamomum_camphora_GWHPBGXC005740 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC005740
cinnamomum_camphora_GWHPBGXC006223 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC006223
cinnamomum_camphora_GWHPBGXC006439 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC006439
cinnamomum_camphora_GWHPBGXC006444 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC006444
cinnamomum_camphora_GWHPBGXC006603 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC006603
cinnamomum_camphora_GWHPBGXC006625 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC006625
cinnamomum_camphora_GWHPBGXC006669 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC006669
cinnamomum_camphora_GWHPBGXC006902 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC006902
cinnamomum_camphora_GWHPBGXC007018 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC007018
cinnamomum_camphora_GWHPBGXC007180 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC007180
cinnamomum_camphora_GWHPBGXC007336 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC007336
cinnamomum_camphora_GWHPBGXC007349 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC007349
cinnamomum_camphora_GWHPBGXC007402 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC007402
cinnamomum_camphora_GWHPBGXC007433 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC007433
cinnamomum_camphora_GWHPBGXC007435 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC007435
cinnamomum_camphora_GWHPBGXC007491 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC007491
cinnamomum_camphora_GWHPBGXC007493 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC007493
cinnamomum_camphora_GWHPBGXC007613 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC007613
cinnamomum_camphora_GWHPBGXC007614 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC007614
cinnamomum_camphora_GWHPBGXC007656 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC007656
cinnamomum_camphora_GWHPBGXC007812 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC007812
cinnamomum_camphora_GWHPBGXC007815 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC007815
cinnamomum_camphora_GWHPBGXC007943 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC007943
cinnamomum_camphora_GWHPBGXC008163 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC008163
cinnamomum_camphora_GWHPBGXC008176 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC008176
cinnamomum_camphora_GWHPBGXC008185 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC008185
cinnamomum_camphora_GWHPBGXC008267 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC008267
cinnamomum_camphora_GWHPBGXC008272 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC008272
cinnamomum_camphora_GWHPBGXC008287 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC008287
cinnamomum_camphora_GWHPBGXC008301 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC008301