PlantSME Plant secondary metabolism enzyme database
Phenylpropanoid portable pathway

Phenylpropanoid portable pathway

Category：Phenylpropanoid pathway

Phenylpropanoid pathway definition imported from the 2026-05-17 portable BLAST/HMM package.

Representative Phenylpropanoid Reaction Route
Entry backbone to monolignol/lignin branches. Substrates, products, and condensed structural formulae show representative conversions; resolved reactions are shown as single enzymes, whereas multi-enzyme branches are shown as curated modules. Member counts come from public annotations.
6 curated steps/modules
Entry Backbone And Lignin Direction
01
Substrate
L-Phenylalanine
C9H11NO2
C6H5-CH2-CH(NH2)-COOH
Deamination to form the phenylpropene acid scaffold
PAL196
Product
trans-Cinnamic acid
C9H8O2
C6H5-CH=CH-COOH
PAL commits the amino-acid substrate to phenylpropanoid metabolism.
02
Substrate
trans-Cinnamic acid
C9H8O2
C6H5-CH=CH-COOH
Para-hydroxylation of the aromatic ring
C4H193
Product
p-Coumaric acid
C9H8O3
4-HO-C6H4-CH=CH-COOH
C4H/CYP73A introduces the 4-hydroxyl group for downstream CoA activation.
03
Substrate
p-Coumaric acid
C9H8O3
4-HO-C6H4-CH=CH-COOH
Substrate
CoA
C21H36N7O16P3S
CoA-SH
CoA ligation and activation
4CL771
Product
p-Coumaroyl-CoA
C30H38N7O18P3S
4-HO-C6H4-CH=CH-C(=O)-SCoA
4CL converts the free acid into a thioester used by condensation, acyltransfer, and reduction reactions.
04
Substrate
p-Coumaroyl-CoA
C30H38N7O18P3S
4-HO-C6H4-CH=CH-C(=O)-SCoA
Hydroxylation, acyl transfer, and methylation
HCT676 C3'H/CYP98A400 CSE681 CCoAOMT130
Product
Feruloyl-CoA-type intermediates
C31H40N7O19P3S
3-MeO-4-HO-C6H3-CH=CH-C(=O)-SCoA
This segment remodels the p-coumaroyl scaffold into caffeoyl/feruloyl-type intermediates.
05
Substrate
Hydroxycinnamoyl-CoA
C30-31 CoA thioesters
Ar-CH=CH-C(=O)-SCoA
Reduction and S/G monolignol formation
CCR505 CAD711 F5H/CYP84A83 COMT604
Product
Coniferyl/sinapyl alcohol
C10H12O3 / C11H14O4
Ar-CH=CH-CH2OH
CCR/CAD and related steps route CoA thioesters toward monolignol monomers.
06
Substrate
Monolignols
C9-C11 phenylpropanoids
Ar-CH=CH-CH2OH
Oxidative coupling and polymerization
LAC945 POD2554
Product
Lignin polymer
(C9 unit)n
[Ar-C3]n ether/C-C polymer
LAC/POD oxidatively couple monolignols into lignin polymers.
Lineage Distribution
Assignments under this module are distributed across the following plant lineages.
All Lineages Basal angiosperms (8449)
Current lineage filter: Basal angiosperms. All species, family, module, and gene statistics below have been narrowed to this lineage.
Algae
Hits0
Bryophytes
Hits0
Lycophytes/Ferns
Hits0
Gymnosperms
Hits0
Basal angiosperms
Hits8449
Monocots
Hits0
Eudicots
Hits0
Species Distribution
Brasenia schreberi
Annona cherimola
Cinnamomum kanehirae
Chloranthus sessilifolius
Amborella trichopoda
Aristolochia contorta
Cinnamomum camphora
Piper nigrum
Liriodendron chinense
Piper longum
Lineage Summary
Basal angiosperms
8449
Module Gene List
Reset
GeneSpeciesProtein ID
cinnamomum_camphora_GWHPBGXC004286 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004286
cinnamomum_camphora_GWHPBGXC004290 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004290
cinnamomum_camphora_GWHPBGXC004296 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004296
cinnamomum_camphora_GWHPBGXC004297 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004297
cinnamomum_camphora_GWHPBGXC004300 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004300
cinnamomum_camphora_GWHPBGXC004301 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004301
cinnamomum_camphora_GWHPBGXC004308 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004308
cinnamomum_camphora_GWHPBGXC004312 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004312
cinnamomum_camphora_GWHPBGXC004319 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004319
cinnamomum_camphora_GWHPBGXC004342 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004342
cinnamomum_camphora_GWHPBGXC004477 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004477
cinnamomum_camphora_GWHPBGXC004507 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004507
cinnamomum_camphora_GWHPBGXC004538 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004538
cinnamomum_camphora_GWHPBGXC004605 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004605
cinnamomum_camphora_GWHPBGXC004618 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004618
cinnamomum_camphora_GWHPBGXC004736 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004736
cinnamomum_camphora_GWHPBGXC004742 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004742
cinnamomum_camphora_GWHPBGXC004743 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004743
cinnamomum_camphora_GWHPBGXC004857 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004857
cinnamomum_camphora_GWHPBGXC004859 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004859
cinnamomum_camphora_GWHPBGXC004948 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004948
cinnamomum_camphora_GWHPBGXC005103 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC005103
cinnamomum_camphora_GWHPBGXC005128 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC005128
cinnamomum_camphora_GWHPBGXC005468 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC005468
cinnamomum_camphora_GWHPBGXC005473 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC005473
cinnamomum_camphora_GWHPBGXC005494 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC005494
cinnamomum_camphora_GWHPBGXC005605 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC005605
cinnamomum_camphora_GWHPBGXC005726 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC005726
cinnamomum_camphora_GWHPBGXC005729 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC005729
cinnamomum_camphora_GWHPBGXC005730 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC005730