PlantSME Plant secondary metabolism enzyme database
Phenylpropanoid portable pathway

Phenylpropanoid portable pathway

Category：Phenylpropanoid pathway

Phenylpropanoid pathway definition imported from the 2026-05-17 portable BLAST/HMM package.

Representative Phenylpropanoid Reaction Route
Entry backbone to monolignol/lignin branches. Substrates, products, and condensed structural formulae show representative conversions; resolved reactions are shown as single enzymes, whereas multi-enzyme branches are shown as curated modules. Member counts come from public annotations.
6 curated steps/modules
Entry Backbone And Lignin Direction
01
Substrate
L-Phenylalanine
C9H11NO2
C6H5-CH2-CH(NH2)-COOH
Deamination to form the phenylpropene acid scaffold
PAL196
Product
trans-Cinnamic acid
C9H8O2
C6H5-CH=CH-COOH
PAL commits the amino-acid substrate to phenylpropanoid metabolism.
02
Substrate
trans-Cinnamic acid
C9H8O2
C6H5-CH=CH-COOH
Para-hydroxylation of the aromatic ring
C4H193
Product
p-Coumaric acid
C9H8O3
4-HO-C6H4-CH=CH-COOH
C4H/CYP73A introduces the 4-hydroxyl group for downstream CoA activation.
03
Substrate
p-Coumaric acid
C9H8O3
4-HO-C6H4-CH=CH-COOH
Substrate
CoA
C21H36N7O16P3S
CoA-SH
CoA ligation and activation
4CL771
Product
p-Coumaroyl-CoA
C30H38N7O18P3S
4-HO-C6H4-CH=CH-C(=O)-SCoA
4CL converts the free acid into a thioester used by condensation, acyltransfer, and reduction reactions.
04
Substrate
p-Coumaroyl-CoA
C30H38N7O18P3S
4-HO-C6H4-CH=CH-C(=O)-SCoA
Hydroxylation, acyl transfer, and methylation
HCT676 C3'H/CYP98A400 CSE681 CCoAOMT130
Product
Feruloyl-CoA-type intermediates
C31H40N7O19P3S
3-MeO-4-HO-C6H3-CH=CH-C(=O)-SCoA
This segment remodels the p-coumaroyl scaffold into caffeoyl/feruloyl-type intermediates.
05
Substrate
Hydroxycinnamoyl-CoA
C30-31 CoA thioesters
Ar-CH=CH-C(=O)-SCoA
Reduction and S/G monolignol formation
CCR505 CAD711 F5H/CYP84A83 COMT604
Product
Coniferyl/sinapyl alcohol
C10H12O3 / C11H14O4
Ar-CH=CH-CH2OH
CCR/CAD and related steps route CoA thioesters toward monolignol monomers.
06
Substrate
Monolignols
C9-C11 phenylpropanoids
Ar-CH=CH-CH2OH
Oxidative coupling and polymerization
LAC945 POD2554
Product
Lignin polymer
(C9 unit)n
[Ar-C3]n ether/C-C polymer
LAC/POD oxidatively couple monolignols into lignin polymers.
Lineage Distribution
Assignments under this module are distributed across the following plant lineages.
All Lineages Basal angiosperms (8449)
Current lineage filter: Basal angiosperms. All species, family, module, and gene statistics below have been narrowed to this lineage.
Algae
Hits0
Bryophytes
Hits0
Lycophytes/Ferns
Hits0
Gymnosperms
Hits0
Basal angiosperms
Hits8449
Monocots
Hits0
Eudicots
Hits0
Species Distribution
Brasenia schreberi
Annona cherimola
Cinnamomum kanehirae
Chloranthus sessilifolius
Amborella trichopoda
Aristolochia contorta
Cinnamomum camphora
Piper nigrum
Liriodendron chinense
Piper longum
Lineage Summary
Basal angiosperms
8449
Module Gene List
Reset
GeneSpeciesProtein ID
cinnamomum_camphora_GWHPBGXC001766 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC001766
cinnamomum_camphora_GWHPBGXC001854 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC001854
cinnamomum_camphora_GWHPBGXC001928 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC001928
cinnamomum_camphora_GWHPBGXC001991 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC001991
cinnamomum_camphora_GWHPBGXC002180 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC002180
cinnamomum_camphora_GWHPBGXC002316 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC002316
cinnamomum_camphora_GWHPBGXC002322 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC002322
cinnamomum_camphora_GWHPBGXC002327 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC002327
cinnamomum_camphora_GWHPBGXC002943 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC002943
cinnamomum_camphora_GWHPBGXC002944 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC002944
cinnamomum_camphora_GWHPBGXC002955 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC002955
cinnamomum_camphora_GWHPBGXC003042 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC003042
cinnamomum_camphora_GWHPBGXC003178 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC003178
cinnamomum_camphora_GWHPBGXC003297 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC003297
cinnamomum_camphora_GWHPBGXC003317 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC003317
cinnamomum_camphora_GWHPBGXC003509 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC003509
cinnamomum_camphora_GWHPBGXC003617 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC003617
cinnamomum_camphora_GWHPBGXC003665 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC003665
cinnamomum_camphora_GWHPBGXC003670 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC003670
cinnamomum_camphora_GWHPBGXC003872 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC003872
cinnamomum_camphora_GWHPBGXC004067 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004067
cinnamomum_camphora_GWHPBGXC004082 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004082
cinnamomum_camphora_GWHPBGXC004159 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004159
cinnamomum_camphora_GWHPBGXC004160 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004160
cinnamomum_camphora_GWHPBGXC004161 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004161
cinnamomum_camphora_GWHPBGXC004165 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004165
cinnamomum_camphora_GWHPBGXC004170 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004170
cinnamomum_camphora_GWHPBGXC004172 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004172
cinnamomum_camphora_GWHPBGXC004214 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004214
cinnamomum_camphora_GWHPBGXC004282 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC004282