PlantSME Plant secondary metabolism enzyme database
Phenylpropanoid portable pathway

Phenylpropanoid portable pathway

Category：Phenylpropanoid pathway

Phenylpropanoid pathway definition imported from the 2026-05-17 portable BLAST/HMM package.

Representative Phenylpropanoid Reaction Route
Entry backbone to monolignol/lignin branches. Substrates, products, and condensed structural formulae show representative conversions; resolved reactions are shown as single enzymes, whereas multi-enzyme branches are shown as curated modules. Member counts come from public annotations.
6 curated steps/modules
Entry Backbone And Lignin Direction
01
Substrate
L-Phenylalanine
C9H11NO2
C6H5-CH2-CH(NH2)-COOH
Deamination to form the phenylpropene acid scaffold
PAL3220
Product
trans-Cinnamic acid
C9H8O2
C6H5-CH=CH-COOH
PAL commits the amino-acid substrate to phenylpropanoid metabolism.
02
Substrate
trans-Cinnamic acid
C9H8O2
C6H5-CH=CH-COOH
Para-hydroxylation of the aromatic ring
C4H1888
Product
p-Coumaric acid
C9H8O3
4-HO-C6H4-CH=CH-COOH
C4H/CYP73A introduces the 4-hydroxyl group for downstream CoA activation.
03
Substrate
p-Coumaric acid
C9H8O3
4-HO-C6H4-CH=CH-COOH
Substrate
CoA
C21H36N7O16P3S
CoA-SH
CoA ligation and activation
4CL7953
Product
p-Coumaroyl-CoA
C30H38N7O18P3S
4-HO-C6H4-CH=CH-C(=O)-SCoA
4CL converts the free acid into a thioester used by condensation, acyltransfer, and reduction reactions.
04
Substrate
p-Coumaroyl-CoA
C30H38N7O18P3S
4-HO-C6H4-CH=CH-C(=O)-SCoA
Hydroxylation, acyl transfer, and methylation
HCT7570 C3'H/CYP98A4224 CSE7936 CCoAOMT1158
Product
Feruloyl-CoA-type intermediates
C31H40N7O19P3S
3-MeO-4-HO-C6H3-CH=CH-C(=O)-SCoA
This segment remodels the p-coumaroyl scaffold into caffeoyl/feruloyl-type intermediates.
05
Substrate
Hydroxycinnamoyl-CoA
C30-31 CoA thioesters
Ar-CH=CH-C(=O)-SCoA
Reduction and S/G monolignol formation
CCR4523 CAD5707 F5H/CYP84A709 COMT4327
Product
Coniferyl/sinapyl alcohol
C10H12O3 / C11H14O4
Ar-CH=CH-CH2OH
CCR/CAD and related steps route CoA thioesters toward monolignol monomers.
06
Substrate
Monolignols
C9-C11 phenylpropanoids
Ar-CH=CH-CH2OH
Oxidative coupling and polymerization
LAC9545 POD33718
Product
Lignin polymer
(C9 unit)n
[Ar-C3]n ether/C-C polymer
LAC/POD oxidatively couple monolignols into lignin polymers.
Lineage Distribution
Assignments under this module are distributed across the following plant lineages.
All Lineages Monocots (92478)
Current lineage filter: Monocots. All species, family, module, and gene statistics below have been narrowed to this lineage.
Algae
Hits0
Bryophytes
Hits0
Lycophytes/Ferns
Hits0
Gymnosperms
Hits0
Basal angiosperms
Hits0
Monocots
Hits92478
Eudicots
Hits0
Species Distribution
Aegilops tauschii
Avena sativa
Triticum turgidum
Cenchrus fungigraminus
Eragrostis nindensis
Hordeum vulgare
Triticum aestivum
Bothriochloa decipiens
Brachypodium hybridum
Digitaria exilis
Lineage Summary
Monocots
92478
Module Gene List
Reset
GeneSpeciesProtein ID
acorus_americanus_Acora.03G042800.1.p acorus_americanus acorus_americanus_Acora.03G042800.1.p
acorus_americanus_Acora.03G067400.1.p acorus_americanus acorus_americanus_Acora.03G067400.1.p
acorus_americanus_Acora.03G078100.1.p acorus_americanus acorus_americanus_Acora.03G078100.1.p
acorus_americanus_Acora.03G082400.1.p acorus_americanus acorus_americanus_Acora.03G082400.1.p
acorus_americanus_Acora.03G109400.1.p acorus_americanus acorus_americanus_Acora.03G109400.1.p
acorus_americanus_Acora.03G119700.1.p acorus_americanus acorus_americanus_Acora.03G119700.1.p
acorus_americanus_Acora.03G134500.1.p acorus_americanus acorus_americanus_Acora.03G134500.1.p
acorus_americanus_Acora.03G140200.1.p acorus_americanus acorus_americanus_Acora.03G140200.1.p
acorus_americanus_Acora.03G141100.1.p acorus_americanus acorus_americanus_Acora.03G141100.1.p
acorus_americanus_Acora.03G143900.1.p acorus_americanus acorus_americanus_Acora.03G143900.1.p
acorus_americanus_Acora.03G144000.1.p acorus_americanus acorus_americanus_Acora.03G144000.1.p
acorus_americanus_Acora.03G144300.1.p acorus_americanus acorus_americanus_Acora.03G144300.1.p
acorus_americanus_Acora.03G162400.1.p acorus_americanus acorus_americanus_Acora.03G162400.1.p
acorus_americanus_Acora.03G181900.1.p acorus_americanus acorus_americanus_Acora.03G181900.1.p
acorus_americanus_Acora.03G187900.1.p acorus_americanus acorus_americanus_Acora.03G187900.1.p
acorus_americanus_Acora.03G193000.1.p acorus_americanus acorus_americanus_Acora.03G193000.1.p
acorus_americanus_Acora.04G003500.1.p acorus_americanus acorus_americanus_Acora.04G003500.1.p
acorus_americanus_Acora.04G006800.1.p acorus_americanus acorus_americanus_Acora.04G006800.1.p
acorus_americanus_Acora.04G011800.1.p acorus_americanus acorus_americanus_Acora.04G011800.1.p
acorus_americanus_Acora.04G011900.1.p acorus_americanus acorus_americanus_Acora.04G011900.1.p
acorus_americanus_Acora.04G019100.1.p acorus_americanus acorus_americanus_Acora.04G019100.1.p
acorus_americanus_Acora.04G021700.1.p acorus_americanus acorus_americanus_Acora.04G021700.1.p
acorus_americanus_Acora.04G023100.1.p acorus_americanus acorus_americanus_Acora.04G023100.1.p
acorus_americanus_Acora.04G032900.1.p acorus_americanus acorus_americanus_Acora.04G032900.1.p
acorus_americanus_Acora.04G033000.1.p acorus_americanus acorus_americanus_Acora.04G033000.1.p
acorus_americanus_Acora.04G033100.1.p acorus_americanus acorus_americanus_Acora.04G033100.1.p
acorus_americanus_Acora.04G038400.1.p acorus_americanus acorus_americanus_Acora.04G038400.1.p
acorus_americanus_Acora.04G046300.1.p acorus_americanus acorus_americanus_Acora.04G046300.1.p
acorus_americanus_Acora.04G046800.1.p acorus_americanus acorus_americanus_Acora.04G046800.1.p
acorus_americanus_Acora.04G051400.1.p acorus_americanus acorus_americanus_Acora.04G051400.1.p