PlantSME Plant secondary metabolism enzyme database
Steroid portable pathway

Steroid portable pathway

Category：Steroid pathway

Steroid pathway definition imported from the 2026-05-17 portable BLAST/HMM package.

Representative Steroid Reaction Route
Squalene to phytosterols and brassinosteroid branch. The steroid route starts from triterpenoid precursors, proceeds through squalene, 2,3-oxidosqualene, and cycloartenol, and then branches toward phytosterols and brassinosteroids; long branches are shown as curated modules.
3 curated steps/modules
Sterol Scaffold Formation
01
Substrate
Farnesyl diphosphate
C15H28O7P2
C15 prenyl-OPP
Squalene synthesis, epoxidation, and cyclization
SQS/FDFT1638 SQE185 CAS2570
Product
Cycloartenol
C30H50O
tetracyclic sterol nucleus with cyclopropyl side
SQS/SQE/CAS convert FPP-derived linear triterpenes into the plant sterol core.
02
Substrate
Cycloartenol-series intermediates
C28-C30 sterols
tetracyclic sterol nucleus
Demethylation, reduction, and side-chain remodeling
SMT1/SMT2/SMT31757 SMO1/SMO21119 CPI1170 CYP51G1313 FK164 HYD1184 DWF71136 DWF5419 DWF1227
Product
Phytosterols
C28H48O / C29H50O
sterol nucleus-C8/C9 side chain
This segment converts cycloartenol-series intermediates into phytosterol pools such as sitosterol and campesterol.
Brassinosteroid Branch
Lineage Distribution
Assignments under this module are distributed across the following plant lineages.
All Lineages Bryophytes (9925)
Current lineage filter: Bryophytes. All species, family, module, and gene statistics below have been narrowed to this lineage.
Algae
Hits0
Bryophytes
Hits9925
Lycophytes/Ferns
Hits0
Gymnosperms
Hits0
Basal angiosperms
Hits0
Monocots
Hits0
Eudicots
Hits0
Species Distribution
Bryum knowltonii
Anthoceros agrestis Oxford
Funaria hygrometrica
Buxbaumia aphylla
Anthoceros punctatus
Calliergon cordifolium
Archidium alternifolium
Fossombronia
Fissidens javanicus
Andreaea rupestris
Lineage Summary
Bryophytes
9925
Module Gene List
Reset
GeneSpeciesProtein ID
GobtHiC_scaffold_20117310 grimmia_obtusifolia GobtHiC_scaffold_20117310
GobtHiC_scaffold_20119820 grimmia_obtusifolia GobtHiC_scaffold_20119820
GobtHiC_scaffold_20121810 grimmia_obtusifolia GobtHiC_scaffold_20121810
GobtHiC_scaffold_20123470 grimmia_obtusifolia GobtHiC_scaffold_20123470
GobtHiC_scaffold_20124040 grimmia_obtusifolia GobtHiC_scaffold_20124040
GobtHiC_scaffold_30139660 grimmia_obtusifolia GobtHiC_scaffold_30139660
GobtHiC_scaffold_30146960 grimmia_obtusifolia GobtHiC_scaffold_30146960
GobtHiC_scaffold_30148690 grimmia_obtusifolia GobtHiC_scaffold_30148690
GobtHiC_scaffold_30154270 grimmia_obtusifolia GobtHiC_scaffold_30154270
GobtHiC_scaffold_40165370 grimmia_obtusifolia GobtHiC_scaffold_40165370
GobtHiC_scaffold_40167040 grimmia_obtusifolia GobtHiC_scaffold_40167040
GobtHiC_scaffold_40167310 grimmia_obtusifolia GobtHiC_scaffold_40167310
GobtHiC_scaffold_40174940 grimmia_obtusifolia GobtHiC_scaffold_40174940
GobtHiC_scaffold_50183880 grimmia_obtusifolia GobtHiC_scaffold_50183880
GobtHiC_scaffold_60211290 grimmia_obtusifolia GobtHiC_scaffold_60211290
GobtHiC_scaffold_70219450 grimmia_obtusifolia GobtHiC_scaffold_70219450
GobtHiC_scaffold_70240020 grimmia_obtusifolia GobtHiC_scaffold_70240020
GobtHiC_scaffold_70243690 grimmia_obtusifolia GobtHiC_scaffold_70243690
GobtHiC_scaffold_70244880 grimmia_obtusifolia GobtHiC_scaffold_70244880
GobtHiC_scaffold_70245320 grimmia_obtusifolia GobtHiC_scaffold_70245320
GobtHiC_scaffold_80251890 grimmia_obtusifolia GobtHiC_scaffold_80251890
GobtHiC_scaffold_80252960 grimmia_obtusifolia GobtHiC_scaffold_80252960
GobtHiC_scaffold_80266110 grimmia_obtusifolia GobtHiC_scaffold_80266110
GobtHiC_scaffold_80271380 grimmia_obtusifolia GobtHiC_scaffold_80271380
GobtHiC_scaffold_80273930 grimmia_obtusifolia GobtHiC_scaffold_80273930
GobtHiC_scaffold_80275470 grimmia_obtusifolia GobtHiC_scaffold_80275470
GobtHiC_scaffold_90277430 grimmia_obtusifolia GobtHiC_scaffold_90277430
GobtHiC_scaffold_90278390 grimmia_obtusifolia GobtHiC_scaffold_90278390
GobtHiC_scaffold_90281000 grimmia_obtusifolia GobtHiC_scaffold_90281000
GobtHiC_scaffold_90290060 grimmia_obtusifolia GobtHiC_scaffold_90290060