PlantSME Plant secondary metabolism enzyme database
Steroid portable pathway

Steroid portable pathway

Category：Steroid pathway

Steroid pathway definition imported from the 2026-05-17 portable BLAST/HMM package.

Representative Steroid Reaction Route
Squalene to phytosterols and brassinosteroid branch. The steroid route starts from triterpenoid precursors, proceeds through squalene, 2,3-oxidosqualene, and cycloartenol, and then branches toward phytosterols and brassinosteroids; long branches are shown as curated modules.
3 curated steps/modules
Sterol Scaffold Formation
01
Substrate
Farnesyl diphosphate
C15H28O7P2
C15 prenyl-OPP
Squalene synthesis, epoxidation, and cyclization
SQS/FDFT1638 SQE185 CAS2570
Product
Cycloartenol
C30H50O
tetracyclic sterol nucleus with cyclopropyl side
SQS/SQE/CAS convert FPP-derived linear triterpenes into the plant sterol core.
02
Substrate
Cycloartenol-series intermediates
C28-C30 sterols
tetracyclic sterol nucleus
Demethylation, reduction, and side-chain remodeling
SMT1/SMT2/SMT31757 SMO1/SMO21119 CPI1170 CYP51G1313 FK164 HYD1184 DWF71136 DWF5419 DWF1227
Product
Phytosterols
C28H48O / C29H50O
sterol nucleus-C8/C9 side chain
This segment converts cycloartenol-series intermediates into phytosterol pools such as sitosterol and campesterol.
Brassinosteroid Branch
Lineage Distribution
Assignments under this module are distributed across the following plant lineages.
All Lineages Bryophytes (9925)
Current lineage filter: Bryophytes. All species, family, module, and gene statistics below have been narrowed to this lineage.
Algae
Hits0
Bryophytes
Hits9925
Lycophytes/Ferns
Hits0
Gymnosperms
Hits0
Basal angiosperms
Hits0
Monocots
Hits0
Eudicots
Hits0
Species Distribution
Bryum knowltonii
Anthoceros agrestis Oxford
Funaria hygrometrica
Buxbaumia aphylla
Anthoceros punctatus
Calliergon cordifolium
Archidium alternifolium
Fossombronia
Fissidens javanicus
Andreaea rupestris
Lineage Summary
Bryophytes
9925
Module Gene List
Reset
GeneSpeciesProtein ID
Haplomitrium10899490088710 haplomitrium Haplomitrium10899490088710
Haplomitrium10902690089770 haplomitrium Haplomitrium10902690089770
Haplomitrium10904180090240 haplomitrium Haplomitrium10904180090240
Haplomitrium10914680094270 haplomitrium Haplomitrium10914680094270
Haplomitrium10921330097040 haplomitrium Haplomitrium10921330097040
Haplomitrium10921480097160 haplomitrium Haplomitrium10921480097160
Haplomitrium10937970105490 haplomitrium Haplomitrium10937970105490
Haplomitrium10942270106870 haplomitrium Haplomitrium10942270106870
Haplomitrium10944690107890 haplomitrium Haplomitrium10944690107890
Haplomitrium10948940110230 haplomitrium Haplomitrium10948940110230
Haplomitrium10950980111680 haplomitrium Haplomitrium10950980111680
Haplomitrium10956080113980 haplomitrium Haplomitrium10956080113980
Haplomitrium10996430136810 haplomitrium Haplomitrium10996430136810
Haplomitrium11005130141580 haplomitrium Haplomitrium11005130141580
Haplomitrium11017800148270 haplomitrium Haplomitrium11017800148270
Haplomitrium11018080148540 haplomitrium Haplomitrium11018080148540
Haplomitrium11039100160010 haplomitrium Haplomitrium11039100160010
Haplomitrium11041160160880 haplomitrium Haplomitrium11041160160880
Haplomitrium11042240161540 haplomitrium Haplomitrium11042240161540
Haplomitrium11045060162680 haplomitrium Haplomitrium11045060162680
Haplomitrium11045060162690 haplomitrium Haplomitrium11045060162690
Haplomitrium11045320162910 haplomitrium Haplomitrium11045320162910
Haplomitrium11058810169310 haplomitrium Haplomitrium11058810169310
Haplomitrium11077240176110 haplomitrium Haplomitrium11077240176110
Haplomitrium11082780177720 haplomitrium Haplomitrium11082780177720
Haplomitrium12053970189860 haplomitrium Haplomitrium12053970189860
Haplomitrium12249070191280 haplomitrium Haplomitrium12249070191280
Haplomitrium12249080191340 haplomitrium Haplomitrium12249080191340
Haplomitrium12402530196350 haplomitrium Haplomitrium12402530196350
Haplomitrium12402540196370 haplomitrium Haplomitrium12402540196370