PlantSME Plant secondary metabolism enzyme database
Steroid portable pathway

Steroid portable pathway

Category：Steroid pathway

Steroid pathway definition imported from the 2026-05-17 portable BLAST/HMM package.

Representative Steroid Reaction Route
Squalene to phytosterols and brassinosteroid branch. The steroid route starts from triterpenoid precursors, proceeds through squalene, 2,3-oxidosqualene, and cycloartenol, and then branches toward phytosterols and brassinosteroids; long branches are shown as curated modules.
3 curated steps/modules
Sterol Scaffold Formation
01
Substrate
Farnesyl diphosphate
C15H28O7P2
C15 prenyl-OPP
Squalene synthesis, epoxidation, and cyclization
SQS/FDFT1638 SQE185 CAS2570
Product
Cycloartenol
C30H50O
tetracyclic sterol nucleus with cyclopropyl side
SQS/SQE/CAS convert FPP-derived linear triterpenes into the plant sterol core.
02
Substrate
Cycloartenol-series intermediates
C28-C30 sterols
tetracyclic sterol nucleus
Demethylation, reduction, and side-chain remodeling
SMT1/SMT2/SMT31757 SMO1/SMO21119 CPI1170 CYP51G1313 FK164 HYD1184 DWF71136 DWF5419 DWF1227
Product
Phytosterols
C28H48O / C29H50O
sterol nucleus-C8/C9 side chain
This segment converts cycloartenol-series intermediates into phytosterol pools such as sitosterol and campesterol.
Brassinosteroid Branch
Lineage Distribution
Assignments under this module are distributed across the following plant lineages.
All Lineages Bryophytes (9925)
Current lineage filter: Bryophytes. All species, family, module, and gene statistics below have been narrowed to this lineage.
Algae
Hits0
Bryophytes
Hits9925
Lycophytes/Ferns
Hits0
Gymnosperms
Hits0
Basal angiosperms
Hits0
Monocots
Hits0
Eudicots
Hits0
Species Distribution
Bryum knowltonii
Anthoceros agrestis Oxford
Funaria hygrometrica
Buxbaumia aphylla
Anthoceros punctatus
Calliergon cordifolium
Archidium alternifolium
Fossombronia
Fissidens javanicus
Andreaea rupestris
Lineage Summary
Bryophytes
9925
Module Gene List
Reset
GeneSpeciesProtein ID
AagrOXFutg000053l0138260.3 anthoceros_agrestis_oxford AagrOXFutg000053l0138260.3
AagrOXFutg000053l0138260.4 anthoceros_agrestis_oxford AagrOXFutg000053l0138260.4
AagrOXFutg000053l0138260.5 anthoceros_agrestis_oxford AagrOXFutg000053l0138260.5
AagrOXFutg000058l0147390.1 anthoceros_agrestis_oxford AagrOXFutg000058l0147390.1
AagrOXFutg000059l0152660.1 anthoceros_agrestis_oxford AagrOXFutg000059l0152660.1
AagrOXFutg000059l0152710.1 anthoceros_agrestis_oxford AagrOXFutg000059l0152710.1
AagrOXFutg000061l0154240.1 anthoceros_agrestis_oxford AagrOXFutg000061l0154240.1
AagrOXFutg000063l0155770.1 anthoceros_agrestis_oxford AagrOXFutg000063l0155770.1
AagrOXFutg000063l0159150.1 anthoceros_agrestis_oxford AagrOXFutg000063l0159150.1
AagrOXFutg000063l0159150.2 anthoceros_agrestis_oxford AagrOXFutg000063l0159150.2
AagrOXFutg000063l0159150.3 anthoceros_agrestis_oxford AagrOXFutg000063l0159150.3
AagrOXFutg000063l0159150.4 anthoceros_agrestis_oxford AagrOXFutg000063l0159150.4
AagrOXFutg000077l0169500.1 anthoceros_agrestis_oxford AagrOXFutg000077l0169500.1
AagrOXFutg000077l0169500.2 anthoceros_agrestis_oxford AagrOXFutg000077l0169500.2
AagrOXFutg000077l0169500.3 anthoceros_agrestis_oxford AagrOXFutg000077l0169500.3
AagrOXFutg000077l0169500.4 anthoceros_agrestis_oxford AagrOXFutg000077l0169500.4
AagrOXFutg000077l0169500.5 anthoceros_agrestis_oxford AagrOXFutg000077l0169500.5
AagrOXFutg000077l0169500.6 anthoceros_agrestis_oxford AagrOXFutg000077l0169500.6
AagrOXFutg000077l0169500.7 anthoceros_agrestis_oxford AagrOXFutg000077l0169500.7
AagrOXFutg000077l0171120.1 anthoceros_agrestis_oxford AagrOXFutg000077l0171120.1
AagrOXFutg000083l0181170.1 anthoceros_agrestis_oxford AagrOXFutg000083l0181170.1
AagrOXFutg000083l0181170.2 anthoceros_agrestis_oxford AagrOXFutg000083l0181170.2
AagrOXFutg000083l0181170.3 anthoceros_agrestis_oxford AagrOXFutg000083l0181170.3
AagrOXFutg000083l0181170.4 anthoceros_agrestis_oxford AagrOXFutg000083l0181170.4
AagrOXFutg000083l0181300.1 anthoceros_agrestis_oxford AagrOXFutg000083l0181300.1
AagrOXFutg000083l0184360.1 anthoceros_agrestis_oxford AagrOXFutg000083l0184360.1
AagrOXFutg000083l0184370.1 anthoceros_agrestis_oxford AagrOXFutg000083l0184370.1
AagrOXFutg000087l0189780.1 anthoceros_agrestis_oxford AagrOXFutg000087l0189780.1
AagrOXFutg000087l0189780.2 anthoceros_agrestis_oxford AagrOXFutg000087l0189780.2
AagrOXFutg000091l0193780.1 anthoceros_agrestis_oxford AagrOXFutg000091l0193780.1