PlantSME Plant secondary metabolism enzyme database
Steroid portable pathway

Steroid portable pathway

Category：Steroid pathway

Steroid pathway definition imported from the 2026-05-17 portable BLAST/HMM package.

Representative Steroid Reaction Route
Squalene to phytosterols and brassinosteroid branch. The steroid route starts from triterpenoid precursors, proceeds through squalene, 2,3-oxidosqualene, and cycloartenol, and then branches toward phytosterols and brassinosteroids; long branches are shown as curated modules.
3 curated steps/modules
Sterol Scaffold Formation
01
Substrate
Farnesyl diphosphate
C15H28O7P2
C15 prenyl-OPP
Squalene synthesis, epoxidation, and cyclization
SQS/FDFT190 SQE37 CAS726
Product
Cycloartenol
C30H50O
tetracyclic sterol nucleus with cyclopropyl side
SQS/SQE/CAS convert FPP-derived linear triterpenes into the plant sterol core.
02
Substrate
Cycloartenol-series intermediates
C28-C30 sterols
tetracyclic sterol nucleus
Demethylation, reduction, and side-chain remodeling
SMT1/SMT2/SMT3593 SMO1/SMO2208 CPI118 CYP51G1179 FK18 HYD122 DWF7106 DWF55 DWF128
Product
Phytosterols
C28H48O / C29H50O
sterol nucleus-C8/C9 side chain
This segment converts cycloartenol-series intermediates into phytosterol pools such as sitosterol and campesterol.
Brassinosteroid Branch
Lineage Distribution
Assignments under this module are distributed across the following plant lineages.
All Lineages Basal angiosperms (2224)
Current lineage filter: Basal angiosperms. All species, family, module, and gene statistics below have been narrowed to this lineage.
Algae
Hits0
Bryophytes
Hits0
Lycophytes/Ferns
Hits0
Gymnosperms
Hits0
Basal angiosperms
Hits2224
Monocots
Hits0
Eudicots
Hits0
Species Distribution
Brasenia schreberi
Annona cherimola
Cinnamomum kanehirae
Cinnamomum camphora
Chloranthus sessilifolius
Amborella trichopoda
Piper nigrum
Aristolochia contorta
Nymphaea colorata
Liriodendron chinense
Lineage Summary
Basal angiosperms
2224
Module Gene List
Reset
GeneSpeciesProtein ID
cinnamomum_camphora_GWHPBGXC022701 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC022701
cinnamomum_camphora_GWHPBGXC022713 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC022713
cinnamomum_camphora_GWHPBGXC023383 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC023383
cinnamomum_camphora_GWHPBGXC023759 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC023759
cinnamomum_camphora_GWHPBGXC025121 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC025121
cinnamomum_camphora_GWHPBGXC025226 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC025226
cinnamomum_camphora_GWHPBGXC025644 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC025644
cinnamomum_camphora_GWHPBGXC025887 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC025887
cinnamomum_camphora_GWHPBGXC025905 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC025905
cinnamomum_camphora_GWHPBGXC026701 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC026701
cinnamomum_camphora_GWHPBGXC027006 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC027006
cinnamomum_camphora_GWHPBGXC027074 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC027074
cinnamomum_camphora_GWHPBGXC027803 cinnamomum_camphora cinnamomum_camphora_GWHPBGXC027803
CkanCKAN.scaff00010002250.1 cinnamomum_kanehirae CkanCKAN.scaff00010002250.1
CkanCKAN.scaff00010002950.1 cinnamomum_kanehirae CkanCKAN.scaff00010002950.1
CkanCKAN.scaff00010020510.1 cinnamomum_kanehirae CkanCKAN.scaff00010020510.1
CkanCKAN.scaff00010020520.1 cinnamomum_kanehirae CkanCKAN.scaff00010020520.1
CkanCKAN.scaff00010022250.1 cinnamomum_kanehirae CkanCKAN.scaff00010022250.1
CkanCKAN.scaff00010022260.1 cinnamomum_kanehirae CkanCKAN.scaff00010022260.1
CkanCKAN.scaff00010022270.1 cinnamomum_kanehirae CkanCKAN.scaff00010022270.1
CkanCKAN.scaff00010022280.1 cinnamomum_kanehirae CkanCKAN.scaff00010022280.1
CkanCKAN.scaff00010023730.1 cinnamomum_kanehirae CkanCKAN.scaff00010023730.1
CkanCKAN.scaff00010026960.1 cinnamomum_kanehirae CkanCKAN.scaff00010026960.1
CkanCKAN.scaff00020037950.1 cinnamomum_kanehirae CkanCKAN.scaff00020037950.1
CkanCKAN.scaff00020037960.1 cinnamomum_kanehirae CkanCKAN.scaff00020037960.1
CkanCKAN.scaff00020038180.1 cinnamomum_kanehirae CkanCKAN.scaff00020038180.1
CkanCKAN.scaff00020042120.1 cinnamomum_kanehirae CkanCKAN.scaff00020042120.1
CkanCKAN.scaff00020043230.1 cinnamomum_kanehirae CkanCKAN.scaff00020043230.1
CkanCKAN.scaff00020048510.1 cinnamomum_kanehirae CkanCKAN.scaff00020048510.1
CkanCKAN.scaff00020052960.1 cinnamomum_kanehirae CkanCKAN.scaff00020052960.1