PlantSME Plant secondary metabolism enzyme database
Steroid portable pathway

Steroid portable pathway

Category：Steroid pathway

Steroid pathway definition imported from the 2026-05-17 portable BLAST/HMM package.

Representative Steroid Reaction Route
Squalene to phytosterols and brassinosteroid branch. The steroid route starts from triterpenoid precursors, proceeds through squalene, 2,3-oxidosqualene, and cycloartenol, and then branches toward phytosterols and brassinosteroids; long branches are shown as curated modules.
3 curated steps/modules
Sterol Scaffold Formation
01
Substrate
Farnesyl diphosphate
C15H28O7P2
C15 prenyl-OPP
Squalene synthesis, epoxidation, and cyclization
SQS/FDFT1915 SQE331 CAS8601
Product
Cycloartenol
C30H50O
tetracyclic sterol nucleus with cyclopropyl side
SQS/SQE/CAS convert FPP-derived linear triterpenes into the plant sterol core.
02
Substrate
Cycloartenol-series intermediates
C28-C30 sterols
tetracyclic sterol nucleus
Demethylation, reduction, and side-chain remodeling
SMT1/SMT2/SMT38083 SMO1/SMO22312 CPI1249 CYP51G11047 FK217 HYD1371 DWF7910 DWF5109 DWF1377
Product
Phytosterols
C28H48O / C29H50O
sterol nucleus-C8/C9 side chain
This segment converts cycloartenol-series intermediates into phytosterol pools such as sitosterol and campesterol.
Brassinosteroid Branch
Lineage Distribution
Assignments under this module are distributed across the following plant lineages.
All Lineages Monocots (25337)
Current lineage filter: Monocots. All species, family, module, and gene statistics below have been narrowed to this lineage.
Algae
Hits0
Bryophytes
Hits0
Lycophytes/Ferns
Hits0
Gymnosperms
Hits0
Basal angiosperms
Hits0
Monocots
Hits25337
Eudicots
Hits0
Species Distribution
Aegilops tauschii
Avena sativa
Hordeum vulgare
Triticum turgidum
Cenchrus fungigraminus
Daemonorops jenkinsiana
Eragrostis nindensis
Triticum aestivum
Eleusine coracana
Panicum virgatum
Lineage Summary
Monocots
25337
Module Gene List
Reset
GeneSpeciesProtein ID
acorus_gramineus_AGRA_11042 acorus_gramineus acorus_gramineus_AGRA_11042
acorus_gramineus_AGRA_11452 acorus_gramineus acorus_gramineus_AGRA_11452
acorus_gramineus_AGRA_11454 acorus_gramineus acorus_gramineus_AGRA_11454
acorus_gramineus_AGRA_11698 acorus_gramineus acorus_gramineus_AGRA_11698
acorus_gramineus_AGRA_12013 acorus_gramineus acorus_gramineus_AGRA_12013
acorus_gramineus_AGRA_12128 acorus_gramineus acorus_gramineus_AGRA_12128
acorus_gramineus_AGRA_12857 acorus_gramineus acorus_gramineus_AGRA_12857
acorus_gramineus_AGRA_13386 acorus_gramineus acorus_gramineus_AGRA_13386
acorus_gramineus_AGRA_13420 acorus_gramineus acorus_gramineus_AGRA_13420
acorus_gramineus_AGRA_13421 acorus_gramineus acorus_gramineus_AGRA_13421
acorus_gramineus_AGRA_13422 acorus_gramineus acorus_gramineus_AGRA_13422
acorus_gramineus_AGRA_13771 acorus_gramineus acorus_gramineus_AGRA_13771
acorus_gramineus_AGRA_15321 acorus_gramineus acorus_gramineus_AGRA_15321
acorus_gramineus_AGRA_15577 acorus_gramineus acorus_gramineus_AGRA_15577
acorus_gramineus_AGRA_15585 acorus_gramineus acorus_gramineus_AGRA_15585
acorus_gramineus_AGRA_15685 acorus_gramineus acorus_gramineus_AGRA_15685
acorus_gramineus_AGRA_16171 acorus_gramineus acorus_gramineus_AGRA_16171
acorus_gramineus_AGRA_16184 acorus_gramineus acorus_gramineus_AGRA_16184
acorus_gramineus_AGRA_16186 acorus_gramineus acorus_gramineus_AGRA_16186
acorus_gramineus_AGRA_16596 acorus_gramineus acorus_gramineus_AGRA_16596
acorus_gramineus_AGRA_16747 acorus_gramineus acorus_gramineus_AGRA_16747
acorus_gramineus_AGRA_16978 acorus_gramineus acorus_gramineus_AGRA_16978
acorus_gramineus_AGRA_17087 acorus_gramineus acorus_gramineus_AGRA_17087
acorus_gramineus_AGRA_17156 acorus_gramineus acorus_gramineus_AGRA_17156
acorus_gramineus_AGRA_17261 acorus_gramineus acorus_gramineus_AGRA_17261
acorus_gramineus_AGRA_17262 acorus_gramineus acorus_gramineus_AGRA_17262
acorus_gramineus_AGRA_17264 acorus_gramineus acorus_gramineus_AGRA_17264
acorus_gramineus_AGRA_17763 acorus_gramineus acorus_gramineus_AGRA_17763
acorus_gramineus_AGRA_17829 acorus_gramineus acorus_gramineus_AGRA_17829
acorus_gramineus_AGRA_18375 acorus_gramineus acorus_gramineus_AGRA_18375