PlantSME Plant secondary metabolism enzyme database
Steroid portable pathway

Steroid portable pathway

Category：Steroid pathway

Steroid pathway definition imported from the 2026-05-17 portable BLAST/HMM package.

Representative Steroid Reaction Route
Squalene to phytosterols and brassinosteroid branch. The steroid route starts from triterpenoid precursors, proceeds through squalene, 2,3-oxidosqualene, and cycloartenol, and then branches toward phytosterols and brassinosteroids; long branches are shown as curated modules.
3 curated steps/modules
Sterol Scaffold Formation
01
Substrate
Farnesyl diphosphate
C15H28O7P2
C15 prenyl-OPP
Squalene synthesis, epoxidation, and cyclization
SQS/FDFT1915 SQE331 CAS8601
Product
Cycloartenol
C30H50O
tetracyclic sterol nucleus with cyclopropyl side
SQS/SQE/CAS convert FPP-derived linear triterpenes into the plant sterol core.
02
Substrate
Cycloartenol-series intermediates
C28-C30 sterols
tetracyclic sterol nucleus
Demethylation, reduction, and side-chain remodeling
SMT1/SMT2/SMT38083 SMO1/SMO22312 CPI1249 CYP51G11047 FK217 HYD1371 DWF7910 DWF5109 DWF1377
Product
Phytosterols
C28H48O / C29H50O
sterol nucleus-C8/C9 side chain
This segment converts cycloartenol-series intermediates into phytosterol pools such as sitosterol and campesterol.
Brassinosteroid Branch
Lineage Distribution
Assignments under this module are distributed across the following plant lineages.
All Lineages Monocots (25337)
Current lineage filter: Monocots. All species, family, module, and gene statistics below have been narrowed to this lineage.
Algae
Hits0
Bryophytes
Hits0
Lycophytes/Ferns
Hits0
Gymnosperms
Hits0
Basal angiosperms
Hits0
Monocots
Hits25337
Eudicots
Hits0
Species Distribution
Aegilops tauschii
Avena sativa
Hordeum vulgare
Triticum turgidum
Cenchrus fungigraminus
Daemonorops jenkinsiana
Eragrostis nindensis
Triticum aestivum
Eleusine coracana
Panicum virgatum
Lineage Summary
Monocots
25337
Module Gene List
Reset
GeneSpeciesProtein ID
AVESA.00010b.r1.3AG0413420.1 avena_sativa AVESA.00010b.r1.3AG0413420.1
AVESA.00010b.r1.3AG0416560.1 avena_sativa AVESA.00010b.r1.3AG0416560.1
AVESA.00010b.r1.3AG0446050.1 avena_sativa AVESA.00010b.r1.3AG0446050.1
AVESA.00010b.r1.3AG0450970.1 avena_sativa AVESA.00010b.r1.3AG0450970.1
AVESA.00010b.r1.3CG0451750.1 avena_sativa AVESA.00010b.r1.3CG0451750.1
AVESA.00010b.r1.3CG0451760.1 avena_sativa AVESA.00010b.r1.3CG0451760.1
AVESA.00010b.r1.3CG0452520.1 avena_sativa AVESA.00010b.r1.3CG0452520.1
AVESA.00010b.r1.3CG0454580.1 avena_sativa AVESA.00010b.r1.3CG0454580.1
AVESA.00010b.r1.3CG0459280.1 avena_sativa AVESA.00010b.r1.3CG0459280.1
AVESA.00010b.r1.3CG0460560.1 avena_sativa AVESA.00010b.r1.3CG0460560.1
AVESA.00010b.r1.3CG0460600.1 avena_sativa AVESA.00010b.r1.3CG0460600.1
AVESA.00010b.r1.3CG0489930.1 avena_sativa AVESA.00010b.r1.3CG0489930.1
AVESA.00010b.r1.3CG0499890.1 avena_sativa AVESA.00010b.r1.3CG0499890.1
AVESA.00010b.r1.3CG0504990.1 avena_sativa AVESA.00010b.r1.3CG0504990.1
AVESA.00010b.r1.3CG0506680.1 avena_sativa AVESA.00010b.r1.3CG0506680.1
AVESA.00010b.r1.3CG0510310.1 avena_sativa AVESA.00010b.r1.3CG0510310.1
AVESA.00010b.r1.3CG0511810.1 avena_sativa AVESA.00010b.r1.3CG0511810.1
AVESA.00010b.r1.3CG0512680.2 avena_sativa AVESA.00010b.r1.3CG0512680.2
AVESA.00010b.r1.3DG0546870.1 avena_sativa AVESA.00010b.r1.3DG0546870.1
AVESA.00010b.r1.3DG0551640.1 avena_sativa AVESA.00010b.r1.3DG0551640.1
AVESA.00010b.r1.3DG0553010.1 avena_sativa AVESA.00010b.r1.3DG0553010.1
AVESA.00010b.r1.3DG0559220.1 avena_sativa AVESA.00010b.r1.3DG0559220.1
AVESA.00010b.r1.3DG0559660.1 avena_sativa AVESA.00010b.r1.3DG0559660.1
AVESA.00010b.r1.3DG0564560.1 avena_sativa AVESA.00010b.r1.3DG0564560.1
AVESA.00010b.r1.3DG0570910.1 avena_sativa AVESA.00010b.r1.3DG0570910.1
AVESA.00010b.r1.3DG0571740.1 avena_sativa AVESA.00010b.r1.3DG0571740.1
AVESA.00010b.r1.4AG0583840.1 avena_sativa AVESA.00010b.r1.4AG0583840.1
AVESA.00010b.r1.4AG0583960.1 avena_sativa AVESA.00010b.r1.4AG0583960.1
AVESA.00010b.r1.4AG0588530.1 avena_sativa AVESA.00010b.r1.4AG0588530.1
AVESA.00010b.r1.4AG0591180.1 avena_sativa AVESA.00010b.r1.4AG0591180.1