CAS

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family CAS.

Lineage Coverage

Detected in 783 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 35857 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
Acoe_04G0028220.2	aquilegia_coerulea	Acoe_04G0028220.2
Acoe_04G0028240.1	aquilegia_coerulea	Acoe_04G0028240.1
Acoe_04G0028280.1	aquilegia_coerulea	Acoe_04G0028280.1
Acoe_04G0028280.2	aquilegia_coerulea	Acoe_04G0028280.2
Acoe_04G0028280.3	aquilegia_coerulea	Acoe_04G0028280.3
Acoe_04G0028280.4	aquilegia_coerulea	Acoe_04G0028280.4
Acoe_04G0028280.5	aquilegia_coerulea	Acoe_04G0028280.5
Acoe_04G0028300.1	aquilegia_coerulea	Acoe_04G0028300.1
Acoe_04G0028300.2	aquilegia_coerulea	Acoe_04G0028300.2
Acoe_04G0028300.3	aquilegia_coerulea	Acoe_04G0028300.3
Acoe_04G0028300.4	aquilegia_coerulea	Acoe_04G0028300.4
Acoe_04G0028300.5	aquilegia_coerulea	Acoe_04G0028300.5
Acoe_04G0029830.1	aquilegia_coerulea	Acoe_04G0029830.1
Acoe_04G0029930.1	aquilegia_coerulea	Acoe_04G0029930.1
Acoe_04G0029940.1	aquilegia_coerulea	Acoe_04G0029940.1
Acoe_04G0031450.1	aquilegia_coerulea	Acoe_04G0031450.1
Acoe_04G0031480.1	aquilegia_coerulea	Acoe_04G0031480.1
Acoe_05G0001810.1	aquilegia_coerulea	Acoe_05G0001810.1
Acoe_05G0001820.1	aquilegia_coerulea	Acoe_05G0001820.1
Acoe_05G0005710.1	aquilegia_coerulea	Acoe_05G0005710.1
Acoe_05G0039370.1	aquilegia_coerulea	Acoe_05G0039370.1
Acoe_05G0039400.1	aquilegia_coerulea	Acoe_05G0039400.1
Acoe_05G0039400.2	aquilegia_coerulea	Acoe_05G0039400.2
Acoe_05G0039400.3	aquilegia_coerulea	Acoe_05G0039400.3
Acoe_05G0039400.4	aquilegia_coerulea	Acoe_05G0039400.4
Acoe_05G0039400.5	aquilegia_coerulea	Acoe_05G0039400.5
Acoe_05G0039400.6	aquilegia_coerulea	Acoe_05G0039400.6
Acoe_05G0039400.7	aquilegia_coerulea	Acoe_05G0039400.7
Acoe_05G0039400.8	aquilegia_coerulea	Acoe_05G0039400.8
Acoe_05G0039460.1	aquilegia_coerulea	Acoe_05G0039460.1