CAS

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family CAS.

Lineage Coverage

Detected in 783 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 35857 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
Acoe_05G0041010.1	aquilegia_coerulea	Acoe_05G0041010.1
Acoe_06G0003480.1	aquilegia_coerulea	Acoe_06G0003480.1
Acoe_06G0013350.1	aquilegia_coerulea	Acoe_06G0013350.1
Acoe_06G0019620.1	aquilegia_coerulea	Acoe_06G0019620.1
Acoe_07G0002880.1	aquilegia_coerulea	Acoe_07G0002880.1
Acoe_07G0013790.1	aquilegia_coerulea	Acoe_07G0013790.1
Acoe_07G0013800.1	aquilegia_coerulea	Acoe_07G0013800.1
Acoe_07G0014660.1	aquilegia_coerulea	Acoe_07G0014660.1
Acoe_07G0023940.1	aquilegia_coerulea	Acoe_07G0023940.1
Acoe_07G0023940.2	aquilegia_coerulea	Acoe_07G0023940.2
Acoe_07G0024940.1	aquilegia_coerulea	Acoe_07G0024940.1
Acoe_07G0026130.1	aquilegia_coerulea	Acoe_07G0026130.1
Acoe_07G0026150.1	aquilegia_coerulea	Acoe_07G0026150.1
Acoe_07G0031370.1	aquilegia_coerulea	Acoe_07G0031370.1
Acoe_07G0031390.1	aquilegia_coerulea	Acoe_07G0031390.1
Acoe_07G0031410.1	aquilegia_coerulea	Acoe_07G0031410.1
Acoe_07G0031450.1	aquilegia_coerulea	Acoe_07G0031450.1
Acoe_07G0044030.1	aquilegia_coerulea	Acoe_07G0044030.1
Acoescaffold_1580001080.1	aquilegia_coerulea	Acoescaffold_1580001080.1
Acoescaffold_9050004560.1	aquilegia_coerulea	Acoescaffold_9050004560.1
Acoescaffold_9050004570.1	aquilegia_coerulea	Acoescaffold_9050004570.1
arabidopsis_arenosa_CAE5957669.1	arabidopsis_arenosa	arabidopsis_arenosa_CAE5957669.1
arabidopsis_arenosa_CAE5959159.1	arabidopsis_arenosa	arabidopsis_arenosa_CAE5959159.1
arabidopsis_arenosa_CAE5959165.1	arabidopsis_arenosa	arabidopsis_arenosa_CAE5959165.1
arabidopsis_arenosa_CAE5962779.1	arabidopsis_arenosa	arabidopsis_arenosa_CAE5962779.1
arabidopsis_arenosa_CAE5962780.1	arabidopsis_arenosa	arabidopsis_arenosa_CAE5962780.1
arabidopsis_arenosa_CAE5963203.1	arabidopsis_arenosa	arabidopsis_arenosa_CAE5963203.1
arabidopsis_arenosa_CAE5963277.1	arabidopsis_arenosa	arabidopsis_arenosa_CAE5963277.1
arabidopsis_arenosa_CAE5964574.1	arabidopsis_arenosa	arabidopsis_arenosa_CAE5964574.1
arabidopsis_arenosa_CAE5964576.1	arabidopsis_arenosa	arabidopsis_arenosa_CAE5964576.1