CAS

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family CAS.

Lineage Coverage

Detected in 783 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 35857 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
ara_suecica_KAG7658683.1	arabidopsis_suecica	ara_suecica_KAG7658683.1
ara_suecica_KAG7659047.1	arabidopsis_suecica	ara_suecica_KAG7659047.1
ara_suecica_KAG7660020.1	arabidopsis_suecica	ara_suecica_KAG7660020.1
ara_suecica_KAG7660075.1	arabidopsis_suecica	ara_suecica_KAG7660075.1
ara_suecica_KAG7660076.1	arabidopsis_suecica	ara_suecica_KAG7660076.1
ara_suecica_KAG7660077.1	arabidopsis_suecica	ara_suecica_KAG7660077.1
ara_suecica_KAG7660078.1	arabidopsis_suecica	ara_suecica_KAG7660078.1
ara_suecica_KAG7660079.1	arabidopsis_suecica	ara_suecica_KAG7660079.1
ara_suecica_KAG7660080.1	arabidopsis_suecica	ara_suecica_KAG7660080.1
ara_suecica_KAG7660133.1	arabidopsis_suecica	ara_suecica_KAG7660133.1
Atha01G0033460.1	arabidopsis_thaliana	Atha01G0033460.1
Atha01G0050670.1	arabidopsis_thaliana	Atha01G0050670.1
Atha01G0051300.1	arabidopsis_thaliana	Atha01G0051300.1
Atha01G0051300.2	arabidopsis_thaliana	Atha01G0051300.2
Atha01G0056930.1	arabidopsis_thaliana	Atha01G0056930.1
Atha01G0056930.2	arabidopsis_thaliana	Atha01G0056930.2
Atha01G0056930.3	arabidopsis_thaliana	Atha01G0056930.3
Atha01G0056930.4	arabidopsis_thaliana	Atha01G0056930.4
Atha01G0060290.1	arabidopsis_thaliana	Atha01G0060290.1
Atha01G0068940.1	arabidopsis_thaliana	Atha01G0068940.1
Atha01G0068960.1	arabidopsis_thaliana	Atha01G0068960.1
Atha01G0068960.2	arabidopsis_thaliana	Atha01G0068960.2
Atha01G0069460.1	arabidopsis_thaliana	Atha01G0069460.1
Atha01G0069460.2	arabidopsis_thaliana	Atha01G0069460.2
Atha01G0069470.1	arabidopsis_thaliana	Atha01G0069470.1
Atha01G0069470.2	arabidopsis_thaliana	Atha01G0069470.2
Atha01G0069470.3	arabidopsis_thaliana	Atha01G0069470.3
Atha01G0069470.4	arabidopsis_thaliana	Atha01G0069470.4
Atha01G0069470.5	arabidopsis_thaliana	Atha01G0069470.5
Atha01G0069480.1	arabidopsis_thaliana	Atha01G0069480.1