CAS

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family CAS.

Lineage Coverage

Detected in 783 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 35857 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
aconitum_vilmorinianum_GWHPBRAL004018	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL004018
aconitum_vilmorinianum_GWHPBRAL004455	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL004455
aconitum_vilmorinianum_GWHPBRAL004491	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL004491
aconitum_vilmorinianum_GWHPBRAL006257	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL006257
aconitum_vilmorinianum_GWHPBRAL007652	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL007652
aconitum_vilmorinianum_GWHPBRAL007653	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL007653
aconitum_vilmorinianum_GWHPBRAL008602	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL008602
aconitum_vilmorinianum_GWHPBRAL010469	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL010469
aconitum_vilmorinianum_GWHPBRAL011196	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL011196
aconitum_vilmorinianum_GWHPBRAL012410	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL012410
aconitum_vilmorinianum_GWHPBRAL013817	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL013817
aconitum_vilmorinianum_GWHPBRAL014635	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL014635
aconitum_vilmorinianum_GWHPBRAL014713	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL014713
aconitum_vilmorinianum_GWHPBRAL014715	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL014715
aconitum_vilmorinianum_GWHPBRAL015040	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL015040
aconitum_vilmorinianum_GWHPBRAL015314	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL015314
aconitum_vilmorinianum_GWHPBRAL015320	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL015320
aconitum_vilmorinianum_GWHPBRAL015321	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL015321
aconitum_vilmorinianum_GWHPBRAL015323	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL015323
aconitum_vilmorinianum_GWHPBRAL015327	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL015327
aconitum_vilmorinianum_GWHPBRAL015328	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL015328
aconitum_vilmorinianum_GWHPBRAL015329	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL015329
aconitum_vilmorinianum_GWHPBRAL015486	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL015486
aconitum_vilmorinianum_GWHPBRAL015538	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL015538
aconitum_vilmorinianum_GWHPBRAL015743	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL015743
aconitum_vilmorinianum_GWHPBRAL016244	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL016244
aconitum_vilmorinianum_GWHPBRAL016524	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL016524
aconitum_vilmorinianum_GWHPBRAL016525	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL016525
aconitum_vilmorinianum_GWHPBRAL017394	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL017394
aconitum_vilmorinianum_GWHPBRAL018142	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL018142