CAS

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family CAS.

Lineage Coverage

Detected in 783 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 35857 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
aconitum_vilmorinianum_GWHPBRAL018371	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL018371
aconitum_vilmorinianum_GWHPBRAL018373	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL018373
aconitum_vilmorinianum_GWHPBRAL022561	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL022561
aconitum_vilmorinianum_GWHPBRAL022996	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL022996
aconitum_vilmorinianum_GWHPBRAL023125	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL023125
aconitum_vilmorinianum_GWHPBRAL023278	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL023278
aconitum_vilmorinianum_GWHPBRAL024066	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL024066
aconitum_vilmorinianum_GWHPBRAL025127	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL025127
aconitum_vilmorinianum_GWHPBRAL025133	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL025133
aconitum_vilmorinianum_GWHPBRAL025581	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL025581
aconitum_vilmorinianum_GWHPBRAL025699	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL025699
aconitum_vilmorinianum_GWHPBRAL025702	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL025702
aconitum_vilmorinianum_GWHPBRAL025704	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL025704
aconitum_vilmorinianum_GWHPBRAL025705	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL025705
aconitum_vilmorinianum_GWHPBRAL025718	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL025718
aconitum_vilmorinianum_GWHPBRAL027311	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL027311
aconitum_vilmorinianum_GWHPBRAL027314	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL027314
aconitum_vilmorinianum_GWHPBRAL027659	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL027659
aconitum_vilmorinianum_GWHPBRAL027663	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL027663
aconitum_vilmorinianum_GWHPBRAL027665	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL027665
aconitum_vilmorinianum_GWHPBRAL027667	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL027667
aconitum_vilmorinianum_GWHPBRAL027669	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL027669
aconitum_vilmorinianum_GWHPBRAL027677	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL027677
aconitum_vilmorinianum_GWHPBRAL027687	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL027687
aconitum_vilmorinianum_GWHPBRAL027785	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL027785
aconitum_vilmorinianum_GWHPBRAL029993	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL029993
aconitum_vilmorinianum_GWHPBRAL030074	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL030074
aconitum_vilmorinianum_GWHPBRAL031332	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL031332
aconitum_vilmorinianum_GWHPBRAL033227	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL033227
aconitum_vilmorinianum_GWHPBRAL034735	aconitum_vilmorinianum	aconitum_vilmorinianum_GWHPBRAL034735