CAS

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family CAS.

Lineage Coverage

Detected in 783 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 35857 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
EVM0015712.mRNA1	aristolochia_contorta	EVM0015712.mRNA1
EVM0016432.mRNA1	aristolochia_contorta	EVM0016432.mRNA1
EVM0016719.mRNA1	aristolochia_contorta	EVM0016719.mRNA1
EVM0016764.mRNA1	aristolochia_contorta	EVM0016764.mRNA1
EVM0016821.mRNA1	aristolochia_contorta	EVM0016821.mRNA1
EVM0016945.mRNA1	aristolochia_contorta	EVM0016945.mRNA1
EVM0017398.mRNA1	aristolochia_contorta	EVM0017398.mRNA1
armoracia_rusticana_Arr10978	armoracia_rusticana	armoracia_rusticana_Arr10978
armoracia_rusticana_Arr11111	armoracia_rusticana	armoracia_rusticana_Arr11111
armoracia_rusticana_Arr12029	armoracia_rusticana	armoracia_rusticana_Arr12029
armoracia_rusticana_Arr13101	armoracia_rusticana	armoracia_rusticana_Arr13101
armoracia_rusticana_Arr13612	armoracia_rusticana	armoracia_rusticana_Arr13612
armoracia_rusticana_Arr16083	armoracia_rusticana	armoracia_rusticana_Arr16083
armoracia_rusticana_Arr18359	armoracia_rusticana	armoracia_rusticana_Arr18359
armoracia_rusticana_Arr18971	armoracia_rusticana	armoracia_rusticana_Arr18971
armoracia_rusticana_Arr19866	armoracia_rusticana	armoracia_rusticana_Arr19866
armoracia_rusticana_Arr22141	armoracia_rusticana	armoracia_rusticana_Arr22141
armoracia_rusticana_Arr23574	armoracia_rusticana	armoracia_rusticana_Arr23574
armoracia_rusticana_Arr23607	armoracia_rusticana	armoracia_rusticana_Arr23607
armoracia_rusticana_Arr23608	armoracia_rusticana	armoracia_rusticana_Arr23608
armoracia_rusticana_Arr24693	armoracia_rusticana	armoracia_rusticana_Arr24693
armoracia_rusticana_Arr24831	armoracia_rusticana	armoracia_rusticana_Arr24831
armoracia_rusticana_Arr24832	armoracia_rusticana	armoracia_rusticana_Arr24832
armoracia_rusticana_Arr24833	armoracia_rusticana	armoracia_rusticana_Arr24833
armoracia_rusticana_Arr25227	armoracia_rusticana	armoracia_rusticana_Arr25227
armoracia_rusticana_Arr26395	armoracia_rusticana	armoracia_rusticana_Arr26395
armoracia_rusticana_Arr29037	armoracia_rusticana	armoracia_rusticana_Arr29037
armoracia_rusticana_Arr30750	armoracia_rusticana	armoracia_rusticana_Arr30750
armoracia_rusticana_Arr30773	armoracia_rusticana	armoracia_rusticana_Arr30773
armoracia_rusticana_Arr33107	armoracia_rusticana	armoracia_rusticana_Arr33107