PlantSME Plant secondary metabolism enzyme database
CAS

CAS

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family CAS.

Lineage Coverage
Detected in 783 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Hordeum vulgare
Triticum turgidum
Aegilops tauschii
Pinus taeda
Related Modules
Steroid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Steroid pathway 35857 current-family members Du et al. 2022; Zebosi et al. 2024
Sterol precursor formation
SQS/FDFT1 4389 SQE 4569 CAS 35857
Phytosterol backbone
SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689
Brassinosteroid branch
DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68
Family Gene List
GeneSpeciesProtein ID
andrographis_paniculata_XP_051125787.1 andrographis_paniculata andrographis_paniculata_XP_051125787.1
andrographis_paniculata_XP_051125788.1 andrographis_paniculata andrographis_paniculata_XP_051125788.1
andrographis_paniculata_XP_051125827.1 andrographis_paniculata andrographis_paniculata_XP_051125827.1
andrographis_paniculata_XP_051125828.1 andrographis_paniculata andrographis_paniculata_XP_051125828.1
andrographis_paniculata_XP_051125829.1 andrographis_paniculata andrographis_paniculata_XP_051125829.1
andrographis_paniculata_XP_051125999.1 andrographis_paniculata andrographis_paniculata_XP_051125999.1
andrographis_paniculata_XP_051127158.1 andrographis_paniculata andrographis_paniculata_XP_051127158.1
andrographis_paniculata_XP_051127563.1 andrographis_paniculata andrographis_paniculata_XP_051127563.1
andrographis_paniculata_XP_051127568.1 andrographis_paniculata andrographis_paniculata_XP_051127568.1
andrographis_paniculata_XP_051127573.1 andrographis_paniculata andrographis_paniculata_XP_051127573.1
andrographis_paniculata_XP_051127579.1 andrographis_paniculata andrographis_paniculata_XP_051127579.1
andrographis_paniculata_XP_051128034.1 andrographis_paniculata andrographis_paniculata_XP_051128034.1
andrographis_paniculata_XP_051128035.1 andrographis_paniculata andrographis_paniculata_XP_051128035.1
andrographis_paniculata_XP_051128036.1 andrographis_paniculata andrographis_paniculata_XP_051128036.1
andrographis_paniculata_XP_051128037.1 andrographis_paniculata andrographis_paniculata_XP_051128037.1
andrographis_paniculata_XP_051128103.1 andrographis_paniculata andrographis_paniculata_XP_051128103.1
andrographis_paniculata_XP_051128394.1 andrographis_paniculata andrographis_paniculata_XP_051128394.1
andrographis_paniculata_XP_051128395.1 andrographis_paniculata andrographis_paniculata_XP_051128395.1
andrographis_paniculata_XP_051128396.1 andrographis_paniculata andrographis_paniculata_XP_051128396.1
andrographis_paniculata_XP_051128397.1 andrographis_paniculata andrographis_paniculata_XP_051128397.1
andrographis_paniculata_XP_051128398.1 andrographis_paniculata andrographis_paniculata_XP_051128398.1
andrographis_paniculata_XP_051128400.1 andrographis_paniculata andrographis_paniculata_XP_051128400.1
andrographis_paniculata_XP_051128401.1 andrographis_paniculata andrographis_paniculata_XP_051128401.1
andrographis_paniculata_XP_051128402.1 andrographis_paniculata andrographis_paniculata_XP_051128402.1
andrographis_paniculata_XP_051128725.1 andrographis_paniculata andrographis_paniculata_XP_051128725.1
andrographis_paniculata_XP_051131775.1 andrographis_paniculata andrographis_paniculata_XP_051131775.1
andrographis_paniculata_XP_051131776.1 andrographis_paniculata andrographis_paniculata_XP_051131776.1
andrographis_paniculata_XP_051132556.1 andrographis_paniculata andrographis_paniculata_XP_051132556.1
andrographis_paniculata_XP_051134212.1 andrographis_paniculata andrographis_paniculata_XP_051134212.1
andrographis_paniculata_XP_051134823.1 andrographis_paniculata andrographis_paniculata_XP_051134823.1