PlantSME Plant secondary metabolism enzyme database
CAS

CAS

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family CAS.

Lineage Coverage
Detected in 783 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Hordeum vulgare
Triticum turgidum
Aegilops tauschii
Pinus taeda
Related Modules
Steroid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Steroid pathway 35857 current-family members Du et al. 2022; Zebosi et al. 2024
Sterol precursor formation
SQS/FDFT1 4389 SQE 4569 CAS 35857
Phytosterol backbone
SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689
Brassinosteroid branch
DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68
Family Gene List
GeneSpeciesProtein ID
andrographis_paniculata_XP_051134965.1 andrographis_paniculata andrographis_paniculata_XP_051134965.1
andrographis_paniculata_XP_051134966.1 andrographis_paniculata andrographis_paniculata_XP_051134966.1
andrographis_paniculata_XP_051134967.1 andrographis_paniculata andrographis_paniculata_XP_051134967.1
andrographis_paniculata_XP_051135259.1 andrographis_paniculata andrographis_paniculata_XP_051135259.1
andrographis_paniculata_XP_051135498.1 andrographis_paniculata andrographis_paniculata_XP_051135498.1
andrographis_paniculata_XP_051135499.1 andrographis_paniculata andrographis_paniculata_XP_051135499.1
andrographis_paniculata_XP_051135500.1 andrographis_paniculata andrographis_paniculata_XP_051135500.1
andrographis_paniculata_XP_051136797.1 andrographis_paniculata andrographis_paniculata_XP_051136797.1
andrographis_paniculata_XP_051136798.1 andrographis_paniculata andrographis_paniculata_XP_051136798.1
andrographis_paniculata_XP_051136799.1 andrographis_paniculata andrographis_paniculata_XP_051136799.1
andrographis_paniculata_XP_051137466.1 andrographis_paniculata andrographis_paniculata_XP_051137466.1
andrographis_paniculata_XP_051139292.1 andrographis_paniculata andrographis_paniculata_XP_051139292.1
andrographis_paniculata_XP_051141732.1 andrographis_paniculata andrographis_paniculata_XP_051141732.1
andrographis_paniculata_XP_051141781.1 andrographis_paniculata andrographis_paniculata_XP_051141781.1
andrographis_paniculata_XP_051141782.1 andrographis_paniculata andrographis_paniculata_XP_051141782.1
andrographis_paniculata_XP_051141783.1 andrographis_paniculata andrographis_paniculata_XP_051141783.1
andrographis_paniculata_XP_051141784.1 andrographis_paniculata andrographis_paniculata_XP_051141784.1
andrographis_paniculata_XP_051141785.1 andrographis_paniculata andrographis_paniculata_XP_051141785.1
andrographis_paniculata_XP_051141787.1 andrographis_paniculata andrographis_paniculata_XP_051141787.1
andrographis_paniculata_XP_051142485.1 andrographis_paniculata andrographis_paniculata_XP_051142485.1
andrographis_paniculata_XP_051142721.1 andrographis_paniculata andrographis_paniculata_XP_051142721.1
andrographis_paniculata_XP_051142723.1 andrographis_paniculata andrographis_paniculata_XP_051142723.1
andrographis_paniculata_XP_051142724.1 andrographis_paniculata andrographis_paniculata_XP_051142724.1
andrographis_paniculata_XP_051142725.1 andrographis_paniculata andrographis_paniculata_XP_051142725.1
andrographis_paniculata_XP_051142726.1 andrographis_paniculata andrographis_paniculata_XP_051142726.1
andrographis_paniculata_XP_051142727.1 andrographis_paniculata andrographis_paniculata_XP_051142727.1
andrographis_paniculata_XP_051142728.1 andrographis_paniculata andrographis_paniculata_XP_051142728.1
andrographis_paniculata_XP_051142804.1 andrographis_paniculata andrographis_paniculata_XP_051142804.1
andrographis_paniculata_XP_051143157.1 andrographis_paniculata andrographis_paniculata_XP_051143157.1
andrographis_paniculata_XP_051144956.1 andrographis_paniculata andrographis_paniculata_XP_051144956.1