CAS

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family CAS.

Lineage Coverage

Detected in 783 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 35857 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
andrographis_paniculata_XP_051145654.1	andrographis_paniculata	andrographis_paniculata_XP_051145654.1
andrographis_paniculata_XP_051146861.1	andrographis_paniculata	andrographis_paniculata_XP_051146861.1
andrographis_paniculata_XP_051146863.1	andrographis_paniculata	andrographis_paniculata_XP_051146863.1
andrographis_paniculata_XP_051147338.1	andrographis_paniculata	andrographis_paniculata_XP_051147338.1
andrographis_paniculata_XP_051147394.1	andrographis_paniculata	andrographis_paniculata_XP_051147394.1
andrographis_paniculata_XP_051147395.1	andrographis_paniculata	andrographis_paniculata_XP_051147395.1
andrographis_paniculata_XP_051147396.1	andrographis_paniculata	andrographis_paniculata_XP_051147396.1
andrographis_paniculata_XP_051147397.1	andrographis_paniculata	andrographis_paniculata_XP_051147397.1
andrographis_paniculata_XP_051147398.1	andrographis_paniculata	andrographis_paniculata_XP_051147398.1
andrographis_paniculata_XP_051147399.1	andrographis_paniculata	andrographis_paniculata_XP_051147399.1
andrographis_paniculata_XP_051147400.1	andrographis_paniculata	andrographis_paniculata_XP_051147400.1
andrographis_paniculata_XP_051147401.1	andrographis_paniculata	andrographis_paniculata_XP_051147401.1
andrographis_paniculata_XP_051147402.1	andrographis_paniculata	andrographis_paniculata_XP_051147402.1
andrographis_paniculata_XP_051150453.1	andrographis_paniculata	andrographis_paniculata_XP_051150453.1
andrographis_paniculata_XP_051151427.1	andrographis_paniculata	andrographis_paniculata_XP_051151427.1
andrographis_paniculata_XP_051151569.1	andrographis_paniculata	andrographis_paniculata_XP_051151569.1
andrographis_paniculata_XP_051151914.1	andrographis_paniculata	andrographis_paniculata_XP_051151914.1
andrographis_paniculata_XP_051152104.1	andrographis_paniculata	andrographis_paniculata_XP_051152104.1
andrographis_paniculata_XP_051152309.1	andrographis_paniculata	andrographis_paniculata_XP_051152309.1
andrographis_paniculata_XP_051152745.1	andrographis_paniculata	andrographis_paniculata_XP_051152745.1
angelica_sinensis_AS01G03048-RA	angelica_sinensis	angelica_sinensis_AS01G03048-RA
angelica_sinensis_AS01G03054-RA	angelica_sinensis	angelica_sinensis_AS01G03054-RA
angelica_sinensis_AS01G03551-RA	angelica_sinensis	angelica_sinensis_AS01G03551-RA
angelica_sinensis_AS02G01216-RA	angelica_sinensis	angelica_sinensis_AS02G01216-RA
angelica_sinensis_AS02G01972-RA	angelica_sinensis	angelica_sinensis_AS02G01972-RA
angelica_sinensis_AS02G01978-RA	angelica_sinensis	angelica_sinensis_AS02G01978-RA
angelica_sinensis_AS03G00588-RA	angelica_sinensis	angelica_sinensis_AS03G00588-RA
angelica_sinensis_AS03G01230-RA	angelica_sinensis	angelica_sinensis_AS03G01230-RA
angelica_sinensis_AS03G01617-RA	angelica_sinensis	angelica_sinensis_AS03G01617-RA
angelica_sinensis_AS03G02438-RA	angelica_sinensis	angelica_sinensis_AS03G02438-RA