PlantSME Plant secondary metabolism enzyme database
SQE

SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage
Detected in 773 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Fragaria ananassa
Fragaria chiloensis
Rosa multiflora
Gossypium raimondii
Related Modules
Steroid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024
Sterol precursor formation
SQS/FDFT1 4389 SQE 4569 CAS 35857
Phytosterol backbone
SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689
Brassinosteroid branch
DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68
Family Gene List
GeneSpeciesProtein ID
KfedScaffold_400120510.1 kalanchoe_fedtschenkoi KfedScaffold_400120510.1
KfedScaffold_530174350.1 kalanchoe_fedtschenkoi KfedScaffold_530174350.1
KfedScaffold_710234860.1 kalanchoe_fedtschenkoi KfedScaffold_710234860.1
kalanchoe_laxiflora_Kalax.0002s0135.1.p kalanchoe_laxiflora kalanchoe_laxiflora_Kalax.0002s0135.1.p
kalanchoe_laxiflora_Kalax.0015s0139.1.p kalanchoe_laxiflora kalanchoe_laxiflora_Kalax.0015s0139.1.p
kalanchoe_laxiflora_Kalax.0035s0133.1.p kalanchoe_laxiflora kalanchoe_laxiflora_Kalax.0035s0133.1.p
kalanchoe_laxiflora_Kalax.0114s0072.1.p kalanchoe_laxiflora kalanchoe_laxiflora_Kalax.0114s0072.1.p
kalanchoe_laxiflora_Kalax.0266s0038.1.p kalanchoe_laxiflora kalanchoe_laxiflora_Kalax.0266s0038.1.p
kalanchoe_laxiflora_Kalax.0300s0044.1.p kalanchoe_laxiflora kalanchoe_laxiflora_Kalax.0300s0044.1.p
kalanchoe_laxiflora_Kalax.0302s0013.1.p kalanchoe_laxiflora kalanchoe_laxiflora_Kalax.0302s0013.1.p
kalanchoe_laxiflora_Kalax.0377s0058.1.p kalanchoe_laxiflora kalanchoe_laxiflora_Kalax.0377s0058.1.p
kalanchoe_laxiflora_Kalax.0620s0014.1.p kalanchoe_laxiflora kalanchoe_laxiflora_Kalax.0620s0014.1.p
kalanchoe_laxiflora_Kalax.0636s0020.1.p kalanchoe_laxiflora kalanchoe_laxiflora_Kalax.0636s0020.1.p
kalanchoe_laxiflora_Kalax.0703s0008.1.p kalanchoe_laxiflora kalanchoe_laxiflora_Kalax.0703s0008.1.p
kalanchoe_laxiflora_Kalax.0880s0009.1.p kalanchoe_laxiflora kalanchoe_laxiflora_Kalax.0880s0009.1.p
kalanchoe_laxiflora_Kalax.0889s0003.1.p kalanchoe_laxiflora kalanchoe_laxiflora_Kalax.0889s0003.1.p
KoboGWHACBH000000050037820.1 kandelia_obovata KoboGWHACBH000000050037820.1
KoboGWHACBH000000380128480.1 kandelia_obovata KoboGWHACBH000000380128480.1
Kpra1925600036410 kindbergia_praelongum Kpra1925600036410
Kpra2465020189350 kindbergia_praelongum Kpra2465020189350
Kpra2473790192730 kindbergia_praelongum Kpra2473790192730
Kpra2553970258350 kindbergia_praelongum Kpra2553970258350
Lpurscaffold199_cov980066940 lablab_purpureus Lpurscaffold199_cov980066940
Lpurscaffold284_cov970099780 lablab_purpureus Lpurscaffold284_cov970099780
Lpurscaffold605_cov970153310 lablab_purpureus Lpurscaffold605_cov970153310
Lpurscaffold754_cov960178400 lablab_purpureus Lpurscaffold754_cov960178400
Lsat02G0022640.1 lactuca_sativa Lsat02G0022640.1
Lsat02G0022640.2 lactuca_sativa Lsat02G0022640.2
Lsat05G0028990.1 lactuca_sativa Lsat05G0028990.1
Lsat05G0028990.2 lactuca_sativa Lsat05G0028990.2