PlantSME Plant secondary metabolism enzyme database
SQE

SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage
Detected in 773 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Fragaria ananassa
Fragaria chiloensis
Rosa multiflora
Gossypium raimondii
Related Modules
Steroid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024
Sterol precursor formation
SQS/FDFT1 4389 SQE 4569 CAS 35857
Phytosterol backbone
SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689
Brassinosteroid branch
DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68
Family Gene List
GeneSpeciesProtein ID
Lsat05G0028990.3 lactuca_sativa Lsat05G0028990.3
Lsat06G0031170.1 lactuca_sativa Lsat06G0031170.1
Lsat06G0031170.2 lactuca_sativa Lsat06G0031170.2
Lsat07G0024880.1 lactuca_sativa Lsat07G0024880.1
Lsat07G0024880.2 lactuca_sativa Lsat07G0024880.2
Lsic03G0006390.1 lagenaria_siceraria Lsic03G0006390.1
Lsic03G0009930.1 lagenaria_siceraria Lsic03G0009930.1
Lsic04G0014510.1 lagenaria_siceraria Lsic04G0014510.1
Lsic04G0022000.1 lagenaria_siceraria Lsic04G0022000.1
Lsic08G0015520.1 lagenaria_siceraria Lsic08G0015520.1
lagerstroemia_indica_GWHPCAXI002246 lagerstroemia_indica lagerstroemia_indica_GWHPCAXI002246
lagerstroemia_indica_GWHPCAXI002752 lagerstroemia_indica lagerstroemia_indica_GWHPCAXI002752
lagerstroemia_indica_GWHPCAXI002755 lagerstroemia_indica lagerstroemia_indica_GWHPCAXI002755
lagerstroemia_indica_GWHPCAXI004441 lagerstroemia_indica lagerstroemia_indica_GWHPCAXI004441
lagerstroemia_indica_GWHPCAXI008230 lagerstroemia_indica lagerstroemia_indica_GWHPCAXI008230
lagerstroemia_indica_GWHPCAXI014591 lagerstroemia_indica lagerstroemia_indica_GWHPCAXI014591
lagerstroemia_indica_GWHPCAXI014592 lagerstroemia_indica lagerstroemia_indica_GWHPCAXI014592
lagerstroemia_indica_GWHPCAXI014594 lagerstroemia_indica lagerstroemia_indica_GWHPCAXI014594
lagerstroemia_indica_GWHPCAXI014598 lagerstroemia_indica lagerstroemia_indica_GWHPCAXI014598
lagerstroemia_indica_GWHPCAXI017952 lagerstroemia_indica lagerstroemia_indica_GWHPCAXI017952
lagerstroemia_indica_GWHPCAXI022330 lagerstroemia_indica lagerstroemia_indica_GWHPCAXI022330
lagerstroemia_indica_GWHPCAXI024707 lagerstroemia_indica lagerstroemia_indica_GWHPCAXI024707
lagerstroemia_indica_GWHPCAXI026218 lagerstroemia_indica lagerstroemia_indica_GWHPCAXI026218
lagerstroemia_indica_GWHPCAXI030384 lagerstroemia_indica lagerstroemia_indica_GWHPCAXI030384
lagerstroemia_indica_GWHPCAXI032498 lagerstroemia_indica lagerstroemia_indica_GWHPCAXI032498
LalaLA_C111130000630 leavenworthia_alabamica LalaLA_C111130000630
LalaLA_C288490015770 leavenworthia_alabamica LalaLA_C288490015770
LalaLA_scaffold20320181150 leavenworthia_alabamica LalaLA_scaffold20320181150
LalaLA_scaffold20320181160 leavenworthia_alabamica LalaLA_scaffold20320181160
LalaLA_scaffold3490285920 leavenworthia_alabamica LalaLA_scaffold3490285920