SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage

Detected in 773 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
genome_MABA045869	malus_baccata	genome_MABA045869
Mdom00G0006440.1	malus_domestica	Mdom00G0006440.1
Mdom02G0016750.1	malus_domestica	Mdom02G0016750.1
Mdom02G0023610.1	malus_domestica	Mdom02G0023610.1
Mdom05G0009050.1	malus_domestica	Mdom05G0009050.1
Mdom05G0009060.1	malus_domestica	Mdom05G0009060.1
Mdom05G0009070.1	malus_domestica	Mdom05G0009070.1
Mdom05G0009080.1	malus_domestica	Mdom05G0009080.1
Mdom05G0009090.1	malus_domestica	Mdom05G0009090.1
Mdom05G0009100.1	malus_domestica	Mdom05G0009100.1
Mdom05G0009110.1	malus_domestica	Mdom05G0009110.1
Mdom05G0025260.1	malus_domestica	Mdom05G0025260.1
Mdom07G0003620.1	malus_domestica	Mdom07G0003620.1
Mdom07G0003630.1	malus_domestica	Mdom07G0003630.1
Mdom07G0003640.1	malus_domestica	Mdom07G0003640.1
Mdom07G0003650.1	malus_domestica	Mdom07G0003650.1
Mdom07G0003660.1	malus_domestica	Mdom07G0003660.1
Mdom07G0003670.1	malus_domestica	Mdom07G0003670.1
Mdom08G0006820.1	malus_domestica	Mdom08G0006820.1
Mdom09G0024180.1	malus_domestica	Mdom09G0024180.1
Mdom10G0009680.1	malus_domestica	Mdom10G0009680.1
Mdom11G0019750.1	malus_domestica	Mdom11G0019750.1
Mdom15G0005840.1	malus_domestica	Mdom15G0005840.1
Mdom15G0026910.1	malus_domestica	Mdom15G0026910.1
Mx00G0006440.1	malus_x_domestica	Mx00G0006440.1
Mx02G0016750.1	malus_x_domestica	Mx02G0016750.1
Mx02G0023610.1	malus_x_domestica	Mx02G0023610.1
Mx05G0009050.1	malus_x_domestica	Mx05G0009050.1
Mx05G0009060.1	malus_x_domestica	Mx05G0009060.1
Mx05G0009070.1	malus_x_domestica	Mx05G0009070.1