SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage

Detected in 773 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
Mx05G0009080.1	malus_x_domestica	Mx05G0009080.1
Mx05G0009090.1	malus_x_domestica	Mx05G0009090.1
Mx05G0009100.1	malus_x_domestica	Mx05G0009100.1
Mx05G0009110.1	malus_x_domestica	Mx05G0009110.1
Mx05G0025260.1	malus_x_domestica	Mx05G0025260.1
Mx07G0003620.1	malus_x_domestica	Mx07G0003620.1
Mx07G0003630.1	malus_x_domestica	Mx07G0003630.1
Mx07G0003640.1	malus_x_domestica	Mx07G0003640.1
Mx07G0003650.1	malus_x_domestica	Mx07G0003650.1
Mx07G0003660.1	malus_x_domestica	Mx07G0003660.1
Mx07G0003670.1	malus_x_domestica	Mx07G0003670.1
Mx08G0006820.1	malus_x_domestica	Mx08G0006820.1
Mx09G0024180.1	malus_x_domestica	Mx09G0024180.1
Mx10G0009680.1	malus_x_domestica	Mx10G0009680.1
Mx11G0019750.1	malus_x_domestica	Mx11G0019750.1
Mx15G0005840.1	malus_x_domestica	Mx15G0005840.1
Mx15G0026910.1	malus_x_domestica	Mx15G0026910.1
Mind05G0004580.1	mangifera_indica	Mind05G0004580.1
Mind06G0005000.1	mangifera_indica	Mind06G0005000.1
Mind10G0005870.1	mangifera_indica	Mind10G0005870.1
Mind14G0006410.1	mangifera_indica	Mind14G0006410.1
Mind14G0007920.1	mangifera_indica	Mind14G0007920.1
Mind15G0005780.1	mangifera_indica	Mind15G0005780.1
Mind19G0014790.1	mangifera_indica	Mind19G0014790.1
Mind19G0020720.1	mangifera_indica	Mind19G0020720.1
Mind19G0020760.1	mangifera_indica	Mind19G0020760.1
Mesc03G0000430.1	manihot_esculenta	Mesc03G0000430.1
Mesc05G0018030.1	manihot_esculenta	Mesc05G0018030.1
Mesc05G0018030.2	manihot_esculenta	Mesc05G0018030.2
Mesc05G0018030.3	manihot_esculenta	Mesc05G0018030.3