PlantSME Plant secondary metabolism enzyme database
SQE

SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage
Detected in 773 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Fragaria ananassa
Fragaria chiloensis
Rosa multiflora
Gossypium raimondii
Related Modules
Steroid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024
Sterol precursor formation
SQS/FDFT1 4389 SQE 4569 CAS 35857
Phytosterol backbone
SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689
Brassinosteroid branch
DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68
Family Gene List
GeneSpeciesProtein ID
OsatZS9703G0011450.3 oryza_sativa_spzs97 OsatZS9703G0011450.3
OsatZS9703G0011450.4 oryza_sativa_spzs97 OsatZS9703G0011450.4
OsatZS9703G0011450.5 oryza_sativa_spzs97 OsatZS9703G0011450.5
OsatZS9703G0011450.6 oryza_sativa_spzs97 OsatZS9703G0011450.6
OsatZS9703G0011450.7 oryza_sativa_spzs97 OsatZS9703G0011450.7
OsatZS9703G0011450.8 oryza_sativa_spzs97 OsatZS9703G0011450.8
Oluc08G0003110.1 ostreococcus_lucimarinus Oluc08G0003110.1
XP_003080880.2 ostreococcus_tauri XP_003080880.2
ostrya_chinensis_OmuG0000630.1 ostrya_chinensis ostrya_chinensis_OmuG0000630.1
ostrya_chinensis_OmuG0000631.1 ostrya_chinensis ostrya_chinensis_OmuG0000631.1
ostrya_chinensis_OmuG0028181.1 ostrya_chinensis ostrya_chinensis_OmuG0028181.1
oxytropis_ochrocephala_EVM0004788.1 oxytropis_ochrocephala oxytropis_ochrocephala_EVM0004788.1
oxytropis_ochrocephala_EVM0009239.1 oxytropis_ochrocephala oxytropis_ochrocephala_EVM0009239.1
oxytropis_ochrocephala_EVM0013460.1 oxytropis_ochrocephala oxytropis_ochrocephala_EVM0013460.1
oxytropis_ochrocephala_EVM0016293.1 oxytropis_ochrocephala oxytropis_ochrocephala_EVM0016293.1
oxytropis_ochrocephala_EVM0018167.1 oxytropis_ochrocephala oxytropis_ochrocephala_EVM0018167.1
oxytropis_ochrocephala_EVM0025800.1 oxytropis_ochrocephala oxytropis_ochrocephala_EVM0025800.1
oxytropis_ochrocephala_EVM0029867.1 oxytropis_ochrocephala oxytropis_ochrocephala_EVM0029867.1
paeonia_ostii_Pos.gene14266.mRNA-1 paeonia_ostii paeonia_ostii_Pos.gene14266.mRNA-1
paeonia_ostii_Pos.gene27426.mRNA-1 paeonia_ostii paeonia_ostii_Pos.gene27426.mRNA-1
paeonia_ostii_Pos.gene29698.mRNA-1 paeonia_ostii paeonia_ostii_Pos.gene29698.mRNA-1
paeonia_ostii_Pos.gene35333.mRNA-1 paeonia_ostii paeonia_ostii_Pos.gene35333.mRNA-1
paeonia_ostii_Pos.gene37252.mRNA-1 paeonia_ostii paeonia_ostii_Pos.gene37252.mRNA-1
paeonia_ostii_Pos.gene48675.mRNA-1 paeonia_ostii paeonia_ostii_Pos.gene48675.mRNA-1
paeonia_ostii_Pos.gene50950.mRNA-1 paeonia_ostii paeonia_ostii_Pos.gene50950.mRNA-1
Pambctg005300_pilon_pilon_pilon0076530 pallavicinia_ambigua Pambctg005300_pilon_pilon_pilon0076530
Pambctg014050_pilon_pilon_pilon0222270 pallavicinia_ambigua Pambctg014050_pilon_pilon_pilon0222270
Pg_S0129.28 panax_ginseng Pg_S0129.28
Pg_S0341.4 panax_ginseng Pg_S0341.4
Pg_S0967.30 panax_ginseng Pg_S0967.30