SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage

Detected in 773 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
paulownia_fortunei_KAI3451891.1	paulownia_fortunei	paulownia_fortunei_KAI3451891.1
paulownia_fortunei_KAI3460122.1	paulownia_fortunei	paulownia_fortunei_KAI3460122.1
paulownia_fortunei_KAI3462661.1	paulownia_fortunei	paulownia_fortunei_KAI3462661.1
paulownia_fortunei_KAI3465224.1	paulownia_fortunei	paulownia_fortunei_KAI3465224.1
PmarPM0035060120750.1	penium_margaritaceum	PmarPM0035060120750.1
PmarPM0079920219150.1	penium_margaritaceum	PmarPM0079920219150.1
PmarPM0090360238290.1	penium_margaritaceum	PmarPM0090360238290.1
PmarPM0101740256100.1	penium_margaritaceum	PmarPM0101740256100.1
PmarPM0149870319610.1	penium_margaritaceum	PmarPM0149870319610.1
PmarPM0223720385050.1	penium_margaritaceum	PmarPM0223720385050.1
perilla_citriodora_KAH6767009.1	perilla_citriodora	perilla_citriodora_KAH6767009.1
perilla_citriodora_KAH6767033.1	perilla_citriodora	perilla_citriodora_KAH6767033.1
perilla_citriodora_KAH6767258.1	perilla_citriodora	perilla_citriodora_KAH6767258.1
perilla_citriodora_KAH6776360.1	perilla_citriodora	perilla_citriodora_KAH6776360.1
perilla_citriodora_KAH6786356.1	perilla_citriodora	perilla_citriodora_KAH6786356.1
petrea_volubilis_Petvo.15G003980.1	petrea_volubilis	petrea_volubilis_Petvo.15G003980.1
petrea_volubilis_Petvo.3G006390.1	petrea_volubilis	petrea_volubilis_Petvo.3G006390.1
petrea_volubilis_Petvo.6G004800.1	petrea_volubilis	petrea_volubilis_Petvo.6G004800.1
petrea_volubilis_Petvo.6G012410.1	petrea_volubilis	petrea_volubilis_Petvo.6G012410.1
petrea_volubilis_Petvo.6G012550.1	petrea_volubilis	petrea_volubilis_Petvo.6G012550.1
petrea_volubilis_Petvo.8G004530.1	petrea_volubilis	petrea_volubilis_Petvo.8G004530.1
petrea_volubilis_Petvo.9G014980.1	petrea_volubilis	petrea_volubilis_Petvo.9G014980.1
petrea_volubilis_Petvo.9G014990.1	petrea_volubilis	petrea_volubilis_Petvo.9G014990.1
Plae4001270047300	phaeoceros_laevis	Plae4001270047300
Plae4009740157750	phaeoceros_laevis	Plae4009740157750
Paphscaffold10001100.1	phalaenopsis_aphrodite	Paphscaffold10001100.1
Paphscaffold1390043980.1	phalaenopsis_aphrodite	Paphscaffold1390043980.1
Paphscaffold1450049160.1	phalaenopsis_aphrodite	Paphscaffold1450049160.1
Paphscaffold26470121370.1	phalaenopsis_aphrodite	Paphscaffold26470121370.1
Paphscaffold430184980.1	phalaenopsis_aphrodite	Paphscaffold430184980.1